Gd-loaded-RBCs for the assessment of tumor vascular volume bycontrast-enhanced-MRI

Biomaterials

Volumn 58, Issue , 2015, Pages 82-92

  Ferrauto, Giuseppe ^a   Di Gregorio, Enza ^a   Dastrù, Walter ^a   Lanzardo, Stefania ^a   Aime, Silvio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Blood; Gadolinium complexes; Image analysis; Magnetic resonance imaging; Red blood cells; Vascular volume

Indexed keywords

BIOCOMPATIBILITY; BLOOD; CELLS; IMAGE ANALYSIS; MAGNETIC RESONANCE IMAGING; TUMORS;

GADOLINIUM COMPLEXES; IMAGING MODALITY; QUANTITATIVE INFORMATION; RED BLOOD CELL; SPATIAL AND TEMPORAL RESOLUTIONS; TUMOR VASCULARIZATION; TUMOR VASCULATURE; VASCULAR VOLUME;

GADOLINIUM COMPOUNDS;

GADOTERIDOL; BIOMATERIAL; CD31 ANTIGEN; CONTRAST MEDIUM; GADOLINIUM;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL; BREAST CANCER; CANCER GROWTH; CONTRAST ENHANCEMENT; ERYTHROCYTE; ERYTHROCYTE FRAGILITY; FEMALE; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PHOTOACOUSTICS; PRIORITY JOURNAL; TUMOR VASCULARIZATION; TUMOR VOLUME; ANIMAL; BAGG ALBINO MOUSE; BRAIN; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; METABOLISM; MUSCLE; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; VASCULARIZATION;

ANIMALS; ANTIGENS, CD31; BIOCOMPATIBLE MATERIALS; BRAIN; CONTRAST MEDIA; ERYTHROCYTES; FEMALE; GADOLINIUM; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MUSCLES; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; TUMOR BURDEN;

EID: 84929259744     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.04.026     Document Type: Article

References (27)

1. Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
2. Folkman J. Tumor angiogenesis: therapeutic implications. NEngl J Med 1971, 285:1182-1186.
3. Gillies R.J., Bhujwalla Z.M., Evelhoch J., Garwood M., Neeman M., Robinson S.P., et al. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2010, 2:139-151.
4. Pathak A.P., Gimi B., Glunde K., Ackerstaff Artemov D., Bhujwalla Z.M. Molecular and functional imaging of cancer: advances in MRI and MRS. Methods Enzymol 2004, 386:3-60.
5. Shames D.M., Kuwatsuru R., Vexler V., Muhler A., Brash R.C. Magn Res Med 1993, 29:616-622.
6. 1 after slice-selective spin inversion in the isolated cardioplegic rat heart: measurement of a lower bound of intracapillary-extravascular water proton exchange rate. Magn Res Med 1997, 38:917-923.
7. Kiessling F., Morgenstern B., Zhang C. Contrast agents and applications to assess tumor angiogenesis invivo by magnetic resonance imaging. Curr Med Chem 2007, 14:77-91.
8. Barrett T., Brechbiel M., Bernardo M., Choyke P.L. MRI of tumor angiogenesis. JMagn Reson Imaging 2007, 26:235-249.
9. Kuwatsuru R., Shames D.M., Mühler A., Mintorovitch J., Vexler V., Mann J.S., et al. Quantification of tissue plasma volume in rat by contrast-enhanced magnetic resonance imaging. Magn Res Med 1993, 30:76-81.
10. Cohn F., Kuwatsuru R., Shames D.M., Neuder M., Mann J.S., Vexler V., et al. Contrast-enahnced magnetic resonance imaging estimation of altered capillary permeability in experimental mammary carcinomas after x-irradiation. Invest Rad 1994, 29:970-977.
11. Haraldsson B., Regner L., Hultborn R., Weiss L., Rippe B. Transcapillary passage of albumin in mammary tumours and in normal lactating mammary glands of the rat. Acta Physiol Scand 1984, 122:497-505.
12. Vandoorne K., Addadi Y., Neeman M. Visualizing vascular permeability and lymphatic drainage using labeled serum albumin. Angiogenesis 2010, 13:75-85.
13. 2*-weighted contrast-enhanced MRI. Magn Reson Med 2004, 51:961-968.
14. Rosen B.R., Belliveau J.W., Vevea J.M., Brady T.J. Perfusion imaging with NMR contrasts agents. Magn Reson Med 1990, 14:249-265.
15. Christen T., Ni W., Qiu D., Schmiedeskamp H., Bammer R., Moseley M., et al. High-resolution cerebral blood volume imaging in humans using the blood pool contrast agent ferumoxytol. Magn Reson Med 2013, 70:705-710.
16. Varallyay C.G., Nesbit E., Fu R., Gahramanov S., Moloney B., Earl E., et al. High-resolution steady-state cerebral blood volume maps in patients with central nervous system neoplasms using ferumoxytol, a superparamagnetic iron oxide nanoparticle. J Cereb Blood Flow Metab 2013, 33:780-786.
17. Maeda H., Wu J., Sawa T., Matsumura Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. JControl Release 2000, 65:271-284.
18. Stapleton S., Milosevic M., Allen C., Zheng J., Dunne M., Yeung I., et al. A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors. PLoS One 2013, 8. e81157.
19. Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 2010, 7:653-664.
20. Johnson K.M., Tao J.Z., Kennan R.P., Gore J.C. Gadolinium-bearing red cells as blood pool MRI contrast agents. Magn Res Med 1998, 40:133-142.
21. Magnani M., Rossi L. Approaches to erythrocyte-mediated drug delivery. Expert Opin Drug Deliv 2014 May, 11(5):677-687.
22. Magnani M., Pierigè F., Rossi L. Erythrocytes as a novel delivery vehicle for biologics: from enzymes to nucleic acid-based therapeutics. Ther Deliv 2012 Mar, 3(3):405-414.
23. Di Gregorio E., Gianolio E., Stefanìa R., Barutello G., Digilio G., Aime S. On the fate of MRI Gd-based contrast agents in cells. Evidence for extensive degradation of linear complexes upon endosomal internalization. Anal Chem 2013, 85:5627-5631.
24. Longo D. DCE-MRI evaluation of an antiangiogenic DNA-based vaccine treatment comparing two image analysis methods September 5-8, 2012, P480- WMIC 2012 - World Molecular Imaging Congress, Dublin (Ir).
25. Ferrauto G., Delli Castelli D., Di Gregorio E., Langereis S., Burdinski D., Grüll H., et al. Lanthanide-loaded erythrocytes as highly sensitive chemical exchange saturation transfer (CEST) MRI contrast agents. J Am Chem Soc 2014, 136:638-641.
26. Di Gregorio E., Ferrauto G., Gianolio E., Aime S. Contrast Media Mol Imaging 2013, 8(6):475-486.
27. O'Connor J., Jackson A., Parker G. Dynamic contrast-enhanced MRI in clinical trials of antivascular therapies. Nat Rev Clin Oncol 2012, 9(3):167-177.