Huaier extract induces autophagic cell death by inhibiting the mTOR/S6K pathway in breast cancer cells

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Wang, Xiaolong ^a   Qi, Wenwen ^b   Li, Yaming ^b   Zhang, Ning ^a   Dong, Lun ^a   Sun, Mingjuan ^a   Cun, Jinjing ^a   Zhang, Yan ^a   Lv, Shangge ^b   Yang, Qifeng ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL EXTRACT; HUAIER EXTRACT; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT; BRIDGED COMPOUND; HERBACEOUS AGENT; MTOR PROTEIN, HUMAN; MTOR PROTEIN, MOUSE; RIBOSOMAL PROTEIN S6 KINASE, 70KD, POLYPEPTIDE 1; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BALB/C NUDE MOUSE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER CELL; CANCER INHIBITION; CELL ORGANELLE; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DRUG CYTOTOXICITY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUAIER; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; MDA MB 231 CELL LINE; MDA MB 468 CELL LINE; MEDICINAL FUNGUS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR XENOGRAFT; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BREAST TUMOR; CANCER TRANSPLANTATION; CHEMISTRY; DRUG SCREENING; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; TRAMETES; TUMOR CELL LINE;

MAMMALIA; MUS;

ANIMALS; APOPTOSIS; AUTOPHAGY; BIOLOGICAL PRODUCTS; BREAST NEOPLASMS; BRIDGED-RING COMPOUNDS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; IN SITU NICK-END LABELING; MCF-7 CELLS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, SMALL INTERFERING; TOR SERINE-THREONINE KINASES; TRAMETES;

EID: 84940048559     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131771     Document Type: Article

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