Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension

Free Radical Biology and Medicine

Volumn 87, Issue , 2015, Pages 252-262

  Pinheiro, Lucas C ^a   Amaral, Jefferson H ^a   Ferreira, Graziele C ^a   Portella, Rafael L ^a   Ceron, Carla S ^a   Montenegro, Marcelo F ^a   Toledo, Jose Carlos ^a   Tanus Santos, Jose E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Hypertension; Nitrates; Nitrites; Nitrosation; Omeprazole; S Nitrosothiols

Indexed keywords

BUTHIONINE SULFOXIMINE; OMEPRAZOLE; S NITROSOTHIOL; SODIUM NITRATE; SODIUM NITRITE; THIOL; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; FREE RADICAL; NITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION; STOMACH PH; ANIMAL; DISEASE MODEL; DRUG EFFECTS; GASTRIC MUCOSA; HUMAN; HYPERTENSION, RENOVASCULAR; METABOLISM; PATHOLOGY;

RATTUS;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; FREE RADICALS; GASTRIC MUCOSA; HUMANS; HYPERTENSION, RENOVASCULAR; NITRITES; RATS; S-NITROSOTHIOLS; SODIUM NITRITE;

EID: 84940041553     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.06.038     Document Type: Article

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