메뉴 건너뛰기




Volumn 167, Issue 4, 2013, Pages 1199-1205

Contrasting effects of aliskiren versus losartan on hypertensive vascular remodeling

Author keywords

Aliskiren; Angiotensin type II receptor antagonist; Hypertension; Losartan; Matrix metalloproteinases; Vascular remodeling

Indexed keywords

ALISKIREN; COLLAGEN; ELASTIN; LOSARTAN; LOSARTAN POTASSIUM; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PRORENIN RECEPTOR; RENIN INHIBITOR; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84881480028     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.03.137     Document Type: Article
Times cited : (31)

References (41)
  • 1
    • 77949536656 scopus 로고    scopus 로고
    • Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy
    • M. Bader Tissue renin-angiotensin-aldosterone systems: targets for pharmacological therapy Annu Rev Pharmacol Toxicol 50 2010 439 465
    • (2010) Annu Rev Pharmacol Toxicol , vol.50 , pp. 439-465
    • Bader, M.1
  • 2
    • 79958050648 scopus 로고    scopus 로고
    • Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases
    • L.A. Martinez-Lemus, G. Zhao, E.L. Galinanes, and M. Boone Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases Am J Physiol Heart Circ Physiol 300 2011 H2005 H2015
    • (2011) Am J Physiol Heart Circ Physiol , vol.300
    • Martinez-Lemus, L.A.1    Zhao, G.2    Galinanes, E.L.3    Boone, M.4
  • 3
    • 79954524108 scopus 로고    scopus 로고
    • Doxycycline dose-dependently inhibits MMP-2-mediated vascular changes in 2K1C hypertension
    • D.A. Guimaraes, E. Rizzi, and C.S. Ceron Doxycycline dose-dependently inhibits MMP-2-mediated vascular changes in 2K1C hypertension Basic Clin Pharmacol Toxicol 108 2011 318 325
    • (2011) Basic Clin Pharmacol Toxicol , vol.108 , pp. 318-325
    • Guimaraes, D.A.1    Rizzi, E.2    Ceron, C.S.3
  • 4
    • 43949099942 scopus 로고    scopus 로고
    • Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats
    • M.M. Castro, E. Rizzi, and L. Figueiredo-Lopes Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats Atherosclerosis 198 2008 320 331
    • (2008) Atherosclerosis , vol.198 , pp. 320-331
    • Castro, M.M.1    Rizzi, E.2    Figueiredo-Lopes, L.3
  • 6
  • 7
    • 50349096718 scopus 로고    scopus 로고
    • Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: Preventive effect of red wine polyphenols
    • A. Walter, N. Etienne-Selloum, M. Sarr, M.O. Kane, A. Beretz, and V.B. Schini-Kerth Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: preventive effect of red wine polyphenols J Vasc Res 45 2008 386 394
    • (2008) J Vasc Res , vol.45 , pp. 386-394
    • Walter, A.1    Etienne-Selloum, N.2    Sarr, M.3    Kane, M.O.4    Beretz, A.5    Schini-Kerth, V.B.6
  • 8
    • 25444459936 scopus 로고    scopus 로고
    • Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries
    • P. Brassard, F. Amiri, and E.L. Schiffrin Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries Hypertension 46 2005 598 606
    • (2005) Hypertension , vol.46 , pp. 598-606
    • Brassard, P.1    Amiri, F.2    Schiffrin, E.L.3
  • 9
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • G. Nguyen, F. Delarue, C. Burckle, L. Bouzhir, T. Giller, and J.D. Sraer Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin J Clin Invest 109 2002 1417 1427
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 10
    • 77951104782 scopus 로고    scopus 로고
    • Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes
    • M. Sakoda, A. Ichihara, and A. Kurauchi-Mito Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes Am J Hypertens 23 2010 575 580
    • (2010) Am J Hypertens , vol.23 , pp. 575-580
    • Sakoda, M.1    Ichihara, A.2    Kurauchi-Mito, A.3
  • 11
    • 37849044605 scopus 로고    scopus 로고
    • (Pro)renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells
    • M. Sakoda, A. Ichihara, and Y. Kaneshiro (Pro)renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells Hypertens Res 30 2007 1139 1146
    • (2007) Hypertens Res , vol.30 , pp. 1139-1146
    • Sakoda, M.1    Ichihara, A.2    Kaneshiro, Y.3
  • 12
    • 33646501526 scopus 로고    scopus 로고
    • Renin/prorenin receptors
    • G. Nguyen Renin/prorenin receptors Kidney Int 69 2006 1503 1506
    • (2006) Kidney Int , vol.69 , pp. 1503-1506
    • Nguyen, G.1
  • 13
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • D.L. Feldman, L. Jin, and H. Xuan Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats Hypertension 52 2008 130 136
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3
  • 14
    • 79952759673 scopus 로고    scopus 로고
    • Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway
    • G. Liu, H. Hitomi, and N. Hosomi Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway J Hypertens 29 2011 696 705
    • (2011) J Hypertens , vol.29 , pp. 696-705
    • Liu, G.1    Hitomi, H.2    Hosomi, N.3
  • 15
    • 57449084151 scopus 로고    scopus 로고
    • Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure
    • D. Westermann, A. Riad, and O. Lettau Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure Hypertension 52 2008 1068 1075
    • (2008) Hypertension , vol.52 , pp. 1068-1075
    • Westermann, D.1    Riad, A.2    Lettau, O.3
  • 16
    • 70349251477 scopus 로고    scopus 로고
    • Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice
    • E. Yamamoto, K. Kataoka, and Y.F. Dong Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice Hypertension 54 2009 633 638
    • (2009) Hypertension , vol.54 , pp. 633-638
    • Yamamoto, E.1    Kataoka, K.2    Dong, Y.F.3
  • 17
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
    • S. Oparil, S.A. Yarows, S. Patel, H. Fang, J. Zhang, and A. Satlin Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial Lancet 370 2007 221 229
    • (2007) Lancet , vol.370 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 18
    • 77950864155 scopus 로고    scopus 로고
    • Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling
    • M.M. Castro, E. Rizzi, C.M. Prado, M.A. Rossi, J.E. Tanus-Santos, and R.F. Gerlach Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling Matrix Biol 29 2010 194 201
    • (2010) Matrix Biol , vol.29 , pp. 194-201
    • Castro, M.M.1    Rizzi, E.2    Prado, C.M.3    Rossi, M.A.4    Tanus-Santos, J.E.5    Gerlach, R.F.6
  • 19
    • 0042574002 scopus 로고    scopus 로고
    • Integrins as unique receptors for vascular control
    • L.A. Martinez-Lemus, X. Wu, and E. Wilson Integrins as unique receptors for vascular control J Vasc Res 40 2003 211 233
    • (2003) J Vasc Res , vol.40 , pp. 211-233
    • Martinez-Lemus, L.A.1    Wu, X.2    Wilson, E.3
  • 20
    • 0032754564 scopus 로고    scopus 로고
    • Transmural pressure induces matrix-degrading activity in porcine arteries ex vivo
    • N.C. Chesler, D.N. Ku, and Z.S. Galis Transmural pressure induces matrix-degrading activity in porcine arteries ex vivo Am J Physiol 277 1999 H2002 H2009
    • (1999) Am J Physiol , vol.277
    • Chesler, N.C.1    Ku, D.N.2    Galis, Z.S.3
  • 21
    • 42349086752 scopus 로고    scopus 로고
    • Renin inhibition by aliskiren prevents atherosclerosis progression: Comparison with irbesartan, atenolol, and amlodipine
    • J. Nussberger, J.F. Aubert, K. Bouzourene, M. Pellegrin, D. Hayoz, and L. Mazzolai Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine Hypertension 51 2008 1306 1311
    • (2008) Hypertension , vol.51 , pp. 1306-1311
    • Nussberger, J.1    Aubert, J.F.2    Bouzourene, K.3    Pellegrin, M.4    Hayoz, D.5    Mazzolai, L.6
  • 22
    • 79954459188 scopus 로고    scopus 로고
    • Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats
    • M.C. Prieto, R.A. Gonzalez-Villalobos, and F.T. Botros Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats Am J Physiol Renal Physiol 300 2011 F749 F755
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Prieto, M.C.1    Gonzalez-Villalobos, R.A.2    Botros, F.T.3
  • 23
    • 63349099519 scopus 로고    scopus 로고
    • Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension
    • M.M. Castro, E. Rizzi, and G.J. Rodrigues Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension Free Radic Biol Med 46 2009 1298 1307
    • (2009) Free Radic Biol Med , vol.46 , pp. 1298-1307
    • Castro, M.M.1    Rizzi, E.2    Rodrigues, G.J.3
  • 24
    • 77950930269 scopus 로고    scopus 로고
    • Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension
    • C. Ceron, M. Castro, and E. Rizzi Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension Br J Pharmacol 160 2010 77 87
    • (2010) Br J Pharmacol , vol.160 , pp. 77-87
    • Ceron, C.1    Castro, M.2    Rizzi, E.3
  • 25
    • 33845785350 scopus 로고    scopus 로고
    • Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan
    • J.L. Pool, R.E. Schmieder, and M. Azizi Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan Am J Hypertens 20 2007 11 20
    • (2007) Am J Hypertens , vol.20 , pp. 11-20
    • Pool, J.L.1    Schmieder, R.E.2    Azizi, M.3
  • 26
    • 0347479295 scopus 로고    scopus 로고
    • Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
    • A. Stanton, C. Jensen, J. Nussberger, and E. O'Brien Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren Hypertension 42 2003 1137 1143
    • (2003) Hypertension , vol.42 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 27
    • 80051956734 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate downregulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodeling in renovascular hypertension
    • S.B.A. Cau, D.A. Guimaraes, and E. Rizzi Pyrrolidine dithiocarbamate downregulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodeling in renovascular hypertension Br J Pharmacol 164 2011 372 381
    • (2011) Br J Pharmacol , vol.164 , pp. 372-381
    • Cau, S.B.A.1    Guimaraes, D.A.2    Rizzi, E.3
  • 28
    • 27544463037 scopus 로고    scopus 로고
    • Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats
    • M. Wang, J. Zhang, and G. Spinetti Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats Am J Pathol 167 2005 1429 1442
    • (2005) Am J Pathol , vol.167 , pp. 1429-1442
    • Wang, M.1    Zhang, J.2    Spinetti, G.3
  • 29
    • 33745947969 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 activation of transforming growth factor-beta1 (TGF-beta1) and TGF-beta1-type II receptor signaling within the aged arterial wall
    • M. Wang, D. Zhao, and G. Spinetti Matrix metalloproteinase 2 activation of transforming growth factor-beta1 (TGF-beta1) and TGF-beta1-type II receptor signaling within the aged arterial wall Arterioscler Thromb Vasc Biol 26 2006 1503 1509
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1503-1509
    • Wang, M.1    Zhao, D.2    Spinetti, G.3
  • 30
    • 0031941558 scopus 로고    scopus 로고
    • Localization of elastin mRNA and TGF-beta1 in rat aorta and caudal artery as a function of age
    • M. Sauvage, N. Hinglais, and C. Mandet Localization of elastin mRNA and TGF-beta1 in rat aorta and caudal artery as a function of age Cell Tissue Res 291 1998 305 314
    • (1998) Cell Tissue Res , vol.291 , pp. 305-314
    • Sauvage, M.1    Hinglais, N.2    Mandet, C.3
  • 31
    • 0033818244 scopus 로고    scopus 로고
    • Angiotensin II activates collagen i gene through a mechanism involving the MAP/ER kinase pathway
    • P.L. Tharaux, C. Chatziantoniou, F. Fakhouri, and J.C. Dussaule Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway Hypertension 36 2000 330 336
    • (2000) Hypertension , vol.36 , pp. 330-336
    • Tharaux, P.L.1    Chatziantoniou, C.2    Fakhouri, F.3    Dussaule, J.C.4
  • 32
    • 0042661157 scopus 로고    scopus 로고
    • Structure-based design of aliskiren, a novel orally effective renin inhibitor
    • J.M. Wood, J. Maibaum, and J. Rahuel Structure-based design of aliskiren, a novel orally effective renin inhibitor Biochem Biophys Res Commun 308 2003 698 705
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 698-705
    • Wood, J.M.1    Maibaum, J.2    Rahuel, J.3
  • 33
    • 0022545442 scopus 로고
    • Vascular renin-angiotensin system in two-kidney, one clip hypertensive rats
    • T. Okamura, M. Miyazaki, T. Inagami, and N. Toda Vascular renin-angiotensin system in two-kidney, one clip hypertensive rats Hypertension 8 1986 560 565
    • (1986) Hypertension , vol.8 , pp. 560-565
    • Okamura, T.1    Miyazaki, M.2    Inagami, T.3    Toda, N.4
  • 34
    • 0029757982 scopus 로고    scopus 로고
    • Increased vascular collagen and noncollagenous protein synthesis contributes to sustain chronic phase of two-kidney, one-clip renovascular hypertension
    • T. Nakada, Y. Iijima, Y. Kubota, M. Watanabe, M. Ishigooka, and H. Suzuki Increased vascular collagen and noncollagenous protein synthesis contributes to sustain chronic phase of two-kidney, one-clip renovascular hypertension J Urol 156 1996 1180 1185
    • (1996) J Urol , vol.156 , pp. 1180-1185
    • Nakada, T.1    Iijima, Y.2    Kubota, Y.3    Watanabe, M.4    Ishigooka, M.5    Suzuki, H.6
  • 35
    • 34548490929 scopus 로고    scopus 로고
    • Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats
    • C. Krebs, I. Hamming, and S. Sadaghiani Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats Kidney Int 72 2007 725 730
    • (2007) Kidney Int , vol.72 , pp. 725-730
    • Krebs, C.1    Hamming, I.2    Sadaghiani, S.3
  • 36
    • 33845608395 scopus 로고    scopus 로고
    • A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
    • J.H. Schefe, M. Menk, and J. Reinemund A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein Circ Res 99 2006 1355 1366
    • (2006) Circ Res , vol.99 , pp. 1355-1366
    • Schefe, J.H.1    Menk, M.2    Reinemund, J.3
  • 37
    • 56749090710 scopus 로고    scopus 로고
    • Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren
    • J.H. Schefe, C. Neumann, and M. Goebel Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren J Hypertens 26 2008 1787 1794
    • (2008) J Hypertens , vol.26 , pp. 1787-1794
    • Schefe, J.H.1    Neumann, C.2    Goebel, M.3
  • 38
    • 74349117848 scopus 로고    scopus 로고
    • The increase in renin during renin inhibition: Does it result in harmful effects by the (pro)renin receptor?
    • A.H. Danser The increase in renin during renin inhibition: does it result in harmful effects by the (pro)renin receptor? Hypertens Res 33 2010 4 10
    • (2010) Hypertens Res , vol.33 , pp. 4-10
    • Danser, A.H.1
  • 39
    • 42649109044 scopus 로고    scopus 로고
    • Prorenin and (pro)renin receptor: A review of available data from in vitro studies and experimental models in rodents
    • G. Nguyen, and A.H. Danser Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents Exp Physiol 93 2008 557 563
    • (2008) Exp Physiol , vol.93 , pp. 557-563
    • Nguyen, G.1    Danser, A.H.2
  • 40
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Y. Huang, S. Wongamorntham, and J. Kasting Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms Kidney Int 69 2006 105 113
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3
  • 41
    • 0035066845 scopus 로고    scopus 로고
    • Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats
    • R.M. Touyz, G. He, M. El Mabrouk, Q. Diep, V. Mardigyan, and E.L. Schiffrin Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats J Hypertens 19 2001 553 559
    • (2001) J Hypertens , vol.19 , pp. 553-559
    • Touyz, R.M.1    He, G.2    El Mabrouk, M.3    Diep, Q.4    Mardigyan, V.5    Schiffrin, E.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.