Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses

Journal of Molecular and Cellular Cardiology

Volumn 87, Issue , 2015, Pages 138-147

  Zhu, Di ^a,b   Wang, Haichang ^a   Zhang, Jinglong ^a   Zhang, Xiaotian ^a   Xin, Chao ^a   Zhang, Fuyang ^a   Lee, Yan ^a   Zhang, Ling ^a   Lian, Kun ^a   Yan, Wenjun ^a   Ma, Xinliang ^c   Liu, Yi ^a,d   Tao, Ling ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Endothelium; Irisin; Oxidative nitrative stress; Type 2 diabetes

Indexed keywords

GLYCOPROTEIN GP 91; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; IRISIN; PROTEIN KINASE C BETA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VASODILATOR STIMULATED PHOSPHOPROTEIN; ANTIOXIDANT; FIBRONECTIN; FNDC5 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME SYNTHESIS; EX VIVO STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MALE; MOUSE; NITRATIVE STRESS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASODILATATION; ANIMAL; AORTA; BLOOD; COMPLICATION; DRUG EFFECTS; GENETICS; LIPID DIET; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; ANTIOXIDANTS; AORTA; APOPTOSIS; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; ENDOTHELIAL CELLS; FIBRONECTINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; NF-KAPPA B; OXIDATIVE STRESS; VASODILATION;

EID: 84940029766     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.07.015     Document Type: Article

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