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Volumn 108, Issue 22, 2003, Pages 2805-2811

Antioxidative, Antinitrative, and Vasculoprotective Effects of a Peroxisome Proliferator-Activated Receptor-γ Agonist in Hypercholesterolemia

Author keywords

Atherosclerosis; Endothelium; Hypercholesterolemia; Inflammation

Indexed keywords

3 NITROTYROSINE; CHOLESTEROL; GLYCOPROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ROSIGLITAZONE; SUPEROXIDE; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 10744223422     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000097003.49585.5E     Document Type: Article
Times cited : (155)

References (31)
  • 1
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87:840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 2
    • 0034711470 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction
    • Oelze M, Mollnau H, Hoffmann N, et al. Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res. 2000; 87:999-1005.
    • (2000) Circ Res , vol.87 , pp. 999-1005
    • Oelze, M.1    Mollnau, H.2    Hoffmann, N.3
  • 3
    • 0034057069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the cardiovascular system
    • Bishop-Bailey D. Peroxisome proliferator-activated receptors in the cardiovascular system. Br J Pharmacol. 2000;129:823-834.
    • (2000) Br J Pharmacol , vol.129 , pp. 823-834
    • Bishop-Bailey, D.1
  • 4
    • 0037302089 scopus 로고    scopus 로고
    • The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: A placebo-controlled randomized clinical trial
    • Caballero AE, Saouaf R, Lim SC, et al. The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial. Metabolism. 2003;52:173-180.
    • (2003) Metabolism , vol.52 , pp. 173-180
    • Caballero, A.E.1    Saouaf, R.2    Lim, S.C.3
  • 5
    • 0035528852 scopus 로고    scopus 로고
    • PPARγ and atherosclerosis: Effects on cell growth and movement
    • Hsueh WA, Law RE. PPARγ and atherosclerosis: effects on cell growth and movement. Arterioscler Thromb Vasc Biol. 2001;21:1891-1895.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1891-1895
    • Hsueh, W.A.1    Law, R.E.2
  • 6
    • 0034230786 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in vascular biology and atherosclerosis: Emerging insights for evolving paradigms
    • Plutzky J. Peroxisome proliferator-activated receptors in vascular biology and atherosclerosis: emerging insights for evolving paradigms. Curr Atheroscler Rep. 2000;2:327-335.
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 327-335
    • Plutzky, J.1
  • 7
    • 0034997794 scopus 로고    scopus 로고
    • Endothelial protective and antishock effects of a selective estrogen receptor modulator in rats
    • Ma XL, Gao F, Chen J, et al. Endothelial protective and antishock effects of a selective estrogen receptor modulator in rats. Am J Physiol. 2001; 280:H876-H884.
    • (2001) Am J Physiol , vol.280
    • Ma, X.L.1    Gao, F.2    Chen, J.3
  • 8
    • 0034089318 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits
    • Lund DD, Faraci FM, Miller FJ Jr, et al. Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits. Circulation. 2000;101:1027-1033.
    • (2000) Circulation , vol.101 , pp. 1027-1033
    • Lund, D.D.1    Faraci, F.M.2    Miller Jr., F.J.3
  • 9
    • 0037177142 scopus 로고    scopus 로고
    • Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
    • Gao F, Gao E, Yue TL, et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation. 2002;105:1497-1502.
    • (2002) Circulation , vol.105 , pp. 1497-1502
    • Gao, F.1    Gao, E.2    Yue, T.L.3
  • 10
    • 0036231417 scopus 로고    scopus 로고
    • Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury
    • Gao F, Yao CL, Gao EH, et al. Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury. J Pharmacol Exp Ther. 2002;301:1-8.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1-8
    • Gao, F.1    Yao, C.L.2    Gao, E.H.3
  • 11
    • 0038389113 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARγ) expression is decreased in pulmonary hypertension and affects endothelial cell growth
    • Ameshima S, Golpon H, Cool CD, et al. Peroxisome proliferator-activated receptor gamma (PPARγ) expression is decreased in pulmonary hypertension and affects endothelial cell growth. Circ Res. 2003;92: 1162-1169.
    • (2003) Circ Res , vol.92 , pp. 1162-1169
    • Ameshima, S.1    Golpon, H.2    Cool, C.D.3
  • 12
    • 0001102396 scopus 로고    scopus 로고
    • Troglitazone effects on gene expression in human skeletal muscle of type II diabetes involve up-regulation of peroxisome proliferator-activated receptor-gamma
    • Park KS, Ciaraldi TP, Lindgren K, et al. Troglitazone effects on gene expression in human skeletal muscle of type II diabetes involve up-regulation of peroxisome proliferator-activated receptor-gamma. J Clin Endocrinol Metab. 1998;83:2830-2835.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2830-2835
    • Park, K.S.1    Ciaraldi, T.P.2    Lindgren, K.3
  • 13
    • 2442751862 scopus 로고    scopus 로고
    • Use of a PPAR gamma-specific monoclonal antibody to demonstrate thiazolidinediones induce PPAR gamma receptor expression in vitro
    • Su JL, Winegar DA, Wisely GB, et al. Use of a PPAR gamma-specific monoclonal antibody to demonstrate thiazolidinediones induce PPAR gamma receptor expression in vitro. Hybridoma. 1999;18:273-280.
    • (1999) Hybridoma , vol.18 , pp. 273-280
    • Su, J.L.1    Winegar, D.A.2    Wisely, G.B.3
  • 14
    • 0035662567 scopus 로고    scopus 로고
    • Distribution, cellular localization, and postnatal development of VASP and Mena expression in mouse tissues
    • Gambaryan S, Hauser W, Kobsar A, et al. Distribution, cellular localization, and postnatal development of VASP and Mena expression in mouse tissues. Histochem Cell Biol. 2001;116:535-543.
    • (2001) Histochem Cell Biol , vol.116 , pp. 535-543
    • Gambaryan, S.1    Hauser, W.2    Kobsar, A.3
  • 15
    • 6644220045 scopus 로고    scopus 로고
    • Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta
    • Mulsch A, Oelze M, Kloss S, et al. Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta. Circulation. 2001;103:2188-2194.
    • (2001) Circulation , vol.103 , pp. 2188-2194
    • Mulsch, A.1    Oelze, M.2    Kloss, S.3
  • 16
    • 0037040947 scopus 로고    scopus 로고
    • Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling
    • Mollnau H, Wendt M, Szocs K, et al. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res. 2002;90:E58-E65.
    • (2002) Circ Res , vol.90
    • Mollnau, H.1    Wendt, M.2    Szocs, K.3
  • 17
    • 0037010030 scopus 로고    scopus 로고
    • Adverse effects of nitroglycerin treatment on endothelial function, vascular nitrotyrosine levels and cGMP-dependent protein kinase activity in hyperlipidemic Watanabe rabbits
    • Warnholtz A, Mollnau H, Heitzer T, et al. Adverse effects of nitroglycerin treatment on endothelial function, vascular nitrotyrosine levels and cGMP-dependent protein kinase activity in hyperlipidemic Watanabe rabbits. J Am Coll Cardiol. 2002;40:1356-1363.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1356-1363
    • Warnholtz, A.1    Mollnau, H.2    Heitzer, T.3
  • 18
    • 0037177164 scopus 로고    scopus 로고
    • Superoxide production and expression of NOx family proteins in human atherosclerosis
    • Sorescu D, Weiss D, Lassegue B, et al. Superoxide production and expression of NOx family proteins in human atherosclerosis. Circulation. 2002;105:1429-1435.
    • (2002) Circulation , vol.105 , pp. 1429-1435
    • Sorescu, D.1    Weiss, D.2    Lassegue, B.3
  • 19
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik TJ, Mussa S, Gastaldi D, et al. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation. 2002;105: 1656-1662.
    • (2002) Circulation , vol.105 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3
  • 20
    • 0033586639 scopus 로고    scopus 로고
    • Increased NADH-oxidase mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
    • Warnholtz, A, Nickenig G, Schulz E, et al. Increased NADH-oxidase mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation. 1999;99:2027-2033.
    • (1999) Circulation , vol.99 , pp. 2027-2033
    • Warnholtz, A.1    Nickenig, G.2    Schulz, E.3
  • 21
    • 0035193079 scopus 로고    scopus 로고
    • PPARS, metabolic disease and atherosclerosis
    • Fruchart JC, Staels B, Duriez P. PPARS, metabolic disease and atherosclerosis. Pharmacol Res. 2001;44:345-352.
    • (2001) Pharmacol Res , vol.44 , pp. 345-352
    • Fruchart, J.C.1    Staels, B.2    Duriez, P.3
  • 22
    • 0037459356 scopus 로고    scopus 로고
    • PPARs of the heart: Three is a crowd
    • Kelly DP. PPARs of the heart: three is a crowd. Circ Res. 2003;92: 482-484.
    • (2003) Circ Res , vol.92 , pp. 482-484
    • Kelly, D.P.1
  • 23
    • 0034283054 scopus 로고    scopus 로고
    • Potential antiatherogenic mechanisms of ascorbate (vitamin C) and a-tocopherol (vitamin E)
    • Carr AC, Zhu BZ, Frei B. Potential antiatherogenic mechanisms of ascorbate (vitamin C) and a-tocopherol (vitamin E). Circ Res. 2000;87: 349-354.
    • (2000) Circ Res , vol.87 , pp. 349-354
    • Carr, A.C.1    Zhu, B.Z.2    Frei, B.3
  • 24
    • 0030430050 scopus 로고    scopus 로고
    • Carvedilol, a new beta-adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia-reperfusion injury in hypercholesterolemic rabbits
    • Ma XL, Yue TL, Lopez BL, et al. Carvedilol, a new beta-adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia-reperfusion injury in hypercholesterolemic rabbits. J Pharmacol Exp Ther. 1996;277:128-136.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 128-136
    • Ma, X.L.1    Yue, T.L.2    Lopez, B.L.3
  • 25
    • 0035180319 scopus 로고    scopus 로고
    • 2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells
    • 2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism. 2001;50:3-11.
    • (2001) Metabolism , vol.50 , pp. 3-11
    • Inoue, I.1    Goto, Si.2    Matsunaga, T.3
  • 26
    • 0036890498 scopus 로고    scopus 로고
    • Mitochondria, nitric oxide, and cardiovascular dysfunction
    • Ramachandran A, Levonen AL, Brookes PS, et al. Mitochondria, nitric oxide, and cardiovascular dysfunction. Free Radic Biol Med. 2002;33: 1465-1474.
    • (2002) Free Radic Biol Med , vol.33 , pp. 1465-1474
    • Ramachandran, A.1    Levonen, A.L.2    Brookes, P.S.3
  • 27
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri V, Wu HD, Willerson JT, et al. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation. 2000;101:235-238.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3
  • 28
    • 0034121698 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
    • Li M, Pascual G, Glass CK. Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol Cell Biol. 2000;20:4699-4707.
    • (2000) Mol Cell Biol , vol.20 , pp. 4699-4707
    • Li, M.1    Pascual, G.2    Glass, C.K.3
  • 29
    • 0033551134 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric-oxide synthase by 15-deoxy-delta12,14-prostaglandin J2
    • Petrova TV, Akama KT, Van Eldik LJ. Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-delta12,14-prostaglandin J2. Proc Natl Acad Sci USA. 1999;96:4668-4673.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4668-4673
    • Petrova, T.V.1    Akama, K.T.2    Van Eldik, L.J.3
  • 30
    • 0037441344 scopus 로고    scopus 로고
    • Diminished production of nitric oxide synthase cofactor tetrahydrobiopterin by rosiglitazone in adipocytes
    • Linscheid P, Keller U, Blau N, et al. Diminished production of nitric oxide synthase cofactor tetrahydrobiopterin by rosiglitazone in adipocytes. Biochem Pharmacol. 2003;65:593-598.
    • (2003) Biochem Pharmacol , vol.65 , pp. 593-598
    • Linscheid, P.1    Keller, U.2    Blau, N.3
  • 31
    • 0032809445 scopus 로고    scopus 로고
    • Nitric oxide and the vascular endothelium in myocardial ischemia-reperfusion injury
    • Vinten-Johansen J, Zhao ZQ, Nakamura M, et al. Nitric oxide and the vascular endothelium in myocardial ischemia-reperfusion injury. Ann N Y Acad Sci. 1999;874:354-370.
    • (1999) Ann N Y Acad Sci , vol.874 , pp. 354-370
    • Vinten-Johansen, J.1    Zhao, Z.Q.2    Nakamura, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.