Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions

Cellular Signalling

Volumn 27, Issue 7, 2015, Pages 1509-1516

  Kwa, Mei Qi ^a,b,c   Huynh, Jennifer ^a,b,c   Reynolds, Eric C ^a,b   Hamilton, John A ^c   Scholz, Glen M ^a,b,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cleft lip palate; IRF6; Mutation; Protein degradation; RIPK4

Indexed keywords

ANKRD3 PROTEIN, HUMAN; BETA CATENIN; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR; IRF6 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; STRESS ACTIVATED PROTEIN KINASE;

ABNORMALITIES; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CLEFT LIP; CLEFT PALATE; CYST; CYTOPLASM; EYE MALFORMATION; GENETICS; HALF LIFE TIME; HEK293 CELL LINE; HUMAN; KNEE; LIP; METABOLISM; MISSENSE MUTATION; MULTIPLE MALFORMATION SYNDROME; PATHOLOGY; PHOSPHORYLATION; PROMOTER REGION; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; SYNDACTYLY; TRANSCRIPTION INITIATION;

ABNORMALITIES, MULTIPLE; BETA CATENIN; CELL LINE; CLEFT LIP; CLEFT PALATE; CYSTS; CYTOPLASM; EYE ABNORMALITIES; HALF-LIFE; HEK293 CELLS; HUMANS; INTERFERON REGULATORY FACTORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KNEE; LIP; MUTATION, MISSENSE; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SYNDACTYLY; TRANSCRIPTIONAL ACTIVATION;

EID: 84940006300     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.03.005     Document Type: Article

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