-
1
-
-
0042121374
-
Barrier function of the skin: "la raison d'etre" of the epidermis
-
Madison, K. C. (2003) Barrier function of the skin: "la raison d'etre" of the epidermis. J. Invest. Dermatol. 121, 231-241
-
(2003)
J. Invest. Dermatol.
, vol.121
, pp. 231-241
-
-
Madison, K.C.1
-
2
-
-
60749125436
-
Epidermal homeostasis: A balancing act of stem cells in the skin
-
Blanpain, C., and Fuchs, E. (2009) Epidermal homeostasis: a balancing act of stem cells in the skin. Nat. Rev. Mol. Cell Biol. 10, 207-217
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 207-217
-
-
Blanpain, C.1
Fuchs, E.2
-
3
-
-
84856557238
-
From keratinocyte to cancer: The pathogenesis and modeling of cutaneous squamous cell carcinoma
-
Ratushny, V., Gober, M. D., Hick, R., Ridky, T. W., and Seykora, J. T. (2012) From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma. J. Clin. Invest. 122, 464-472
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 464-472
-
-
Ratushny, V.1
Gober, M.D.2
Hick, R.3
Ridky, T.W.4
Seykora, J.T.5
-
4
-
-
33750452339
-
Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)
-
Ingraham, C. R., Kinoshita, A., Kondo, S., Yang, B., Sajan, S., Trout, K. J., Malik, M. I., Dunnwald, M., Goudy, S. L., Lovett, M., Murray, J. C., and Schutte, B. C. (2006) Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6). Nat. Genet. 38, 1335-1340
-
(2006)
Nat. Genet.
, vol.38
, pp. 1335-1340
-
-
Ingraham, C.R.1
Kinoshita, A.2
Kondo, S.3
Yang, B.4
Sajan, S.5
Trout, K.J.6
Malik, M.I.7
Dunnwald, M.8
Goudy, S.L.9
Lovett, M.10
Murray, J.C.11
Schutte, B.C.12
-
5
-
-
33750441851
-
Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch
-
Richardson, R. J., Dixon, J., Malhotra, S., Hardman, M. J., Knowles, L., Boot-Handford, R. P., Shore, P., Whitmarsh, A., and Dixon, M. J. (2006) Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch. Nat. Genet. 38, 1329-1334
-
(2006)
Nat. Genet.
, vol.38
, pp. 1329-1334
-
-
Richardson, R.J.1
Dixon, J.2
Malhotra, S.3
Hardman, M.J.4
Knowles, L.5
Boot-Handford, R.P.6
Shore, P.7
Whitmarsh, A.8
Dixon, M.J.9
-
6
-
-
84856083695
-
Interferon regulatory factor 6 is necessary, but not sufficient, for keratinocyte differentiation
-
Biggs, L. C., Rhea, L., Schutte, B. C., and Dunnwald, M. (2012) Interferon regulatory factor 6 is necessary, but not sufficient, for keratinocyte differentiation. J. Invest. Dermatol. 132, 50-58
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 50-58
-
-
Biggs, L.C.1
Rhea, L.2
Schutte, B.C.3
Dunnwald, M.4
-
7
-
-
84872173203
-
Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3
-
de la Garza, G., Schleiffarth, J. R., Dunnwald, M., Mankad, A., Weirather, J. L., Bonde, G., Butcher, S., Mansour, T. A., Kousa, Y. A., Fukazawa, C. F., Houston, D. W., Manak, J. R., Schutte, B. C., Wagner, D. S., and Cornell, R. A. (2013) Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3. J. Invest. Dermatol. 133, 68-77
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 68-77
-
-
De La Garza, G.1
Schleiffarth, J.R.2
Dunnwald, M.3
Mankad, A.4
Weirather, J.L.5
Bonde, G.6
Butcher, S.7
Mansour, T.A.8
Kousa, Y.A.9
Fukazawa, C.F.10
Houston, D.W.11
Manak, J.R.12
Schutte, B.C.13
Wagner, D.S.14
Cornell, R.A.15
-
8
-
-
80051983047
-
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas
-
Botti, E., Spallone, G., Moretti, F., Marinari, B., Pinetti, V., Galanti, S., De Meo, P. D., De Nicola, F., Ganci, F., Castrignanò, T., Pesole, G., Chimenti, S., Guerrini, L., Fanciulli, M., Blandino, G., Karin, M., and Costanzo, A. (2011) Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. Proc. Natl. Acad. Sci. U.S.A. 108, 13710-13715
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 13710-13715
-
-
Botti, E.1
Spallone, G.2
Moretti, F.3
Marinari, B.4
Pinetti, V.5
Galanti, S.6
De Meo, P.D.7
De Nicola, F.8
Ganci, F.9
Castrignanò, T.10
Pesole, G.11
Chimenti, S.12
Guerrini, L.13
Fanciulli, M.14
Blandino, G.15
Karin, M.16
Costanzo, A.17
-
9
-
-
0037143450
-
RIP4 is an ankyrin repeat-containing kinase essential for keratinocyte differentiation
-
Holland, P., Willis, C., Kanaly, S., Glaccum, M., Warren, A., Charrier, K., Murison, J., Derry, J., Virca, G., Bird, T., and Peschon, J. (2002) RIP4 is an ankyrin repeat-containing kinase essential for keratinocyte differentiation. Curr. Biol. 12, 1424-1428
-
(2002)
Curr. Biol.
, vol.12
, pp. 1424-1428
-
-
Holland, P.1
Willis, C.2
Kanaly, S.3
Glaccum, M.4
Warren, A.5
Charrier, K.6
Murison, J.7
Derry, J.8
Virca, G.9
Bird, T.10
Peschon, J.11
-
10
-
-
72049126367
-
RIP4 regulates epidermal differentiation and cutaneous inflammation
-
Rountree, R. B., Willis, C. R., Dinh, H., Blumberg, H., Bailey, K., Dean, C., Jr., Peschon, J. J., and Holland, P. M. (2010) RIP4 regulates epidermal differentiation and cutaneous inflammation. J. Invest. Dermatol. 130, 102-112
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 102-112
-
-
Rountree, R.B.1
Willis, C.R.2
Dinh, H.3
Blumberg, H.4
Bailey, K.5
Dean, C.6
Peschon, J.J.7
Holland, P.M.8
-
11
-
-
0034680916
-
DIK, a novel protein kinase that interacts with protein kinase Cδ. Cloning, characterization, and gene analysis
-
Bahr, C., Rohwer, A., Stempka, L., Rincke, G., Marks, F., and Gschwendt, M. (2000) DIK, a novel protein kinase that interacts with protein kinase Cδ. Cloning, characterization, and gene analysis. J. Biol. Chem. 275, 36350-36357
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36350-36357
-
-
Bahr, C.1
Rohwer, A.2
Stempka, L.3
Rincke, G.4
Marks, F.5
Gschwendt, M.6
-
12
-
-
0035877645
-
Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase
-
Chen, L., Haider, K., Ponda, M., Cariappa, A., Rowitch, D., and Pillai, S. (2001) Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase. J. Biol. Chem. 276, 21737-21744
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21737-21744
-
-
Chen, L.1
Haider, K.2
Ponda, M.3
Cariappa, A.4
Rowitch, D.5
Pillai, S.6
-
13
-
-
0037199933
-
Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-κ B activation induced by phorbol ester
-
Muto, A., Ruland, J., McAllister-Lucas, L. M., Lucas, P. C., Yamaoka, S., Chen, F. F., Lin, A., Mak, T. W., Núñez, G., and Inohara, N. (2002) Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-κ B activation induced by phorbol ester. J. Biol. Chem. 277, 31871-31876
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31871-31876
-
-
Muto, A.1
Ruland, J.2
McAllister-Lucas, L.M.3
Lucas, P.C.4
Yamaoka, S.5
Chen, F.F.6
Lin, A.7
Mak, T.W.8
Núñez, G.9
Inohara, N.10
-
14
-
-
0037484329
-
Protein kinase C-associated kinase can activate NFκB in both a kinase-dependent and a kinase-independent manner
-
Moran, S. T., Haider, K., Ow, Y., Milton, P., Chen, L., and Pillai, S. (2003) Protein kinase C-associated kinase can activate NFκB in both a kinase-dependent and a kinase-independent manner. J. Biol. Chem. 278, 21526-21533
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21526-21533
-
-
Moran, S.T.1
Haider, K.2
Ow, Y.3
Milton, P.4
Chen, L.5
Pillai, S.6
-
15
-
-
0038824573
-
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-κ B and is processed during apoptosis
-
Meylan, E., Martinon, F., Thome, M., Gschwendt, M., and Tschopp, J. (2002) RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-κ B and is processed during apoptosis. EMBO Rep. 3, 1201-1208
-
(2002)
EMBO Rep.
, vol.3
, pp. 1201-1208
-
-
Meylan, E.1
Martinon, F.2
Thome, M.3
Gschwendt, M.4
Tschopp, J.5
-
16
-
-
84875449391
-
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling
-
Huang, X., McGann, J. C., Liu, B. Y., Hannoush, R. N., Lill, J. R., Pham, V., Newton, K., Kakunda, M., Liu, J., Yu, C., Hymowitz, S. G., Hongo, J. A., Wynshaw-Boris, A., Polakis, P., Harland, R. M., and Dixit, V. M. (2013) Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science 339, 1441-1445
-
(2013)
Science
, vol.339
, pp. 1441-1445
-
-
Huang, X.1
McGann, J.C.2
Liu, B.Y.3
Hannoush, R.N.4
Lill, J.R.5
Pham, V.6
Newton, K.7
Kakunda, M.8
Liu, J.9
Yu, C.10
Hymowitz, S.G.11
Hongo, J.A.12
Wynshaw-Boris, A.13
Polakis, P.14
Harland, R.M.15
Dixit, V.M.16
-
17
-
-
18644374446
-
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
-
Kondo, S., Schutte, B. C., Richardson, R. J., Bjork, B. C., Knight, A. S., Watanabe, Y., Howard, E., de Lima, R. L., Daack-Hirsch, S., Sander, A., McDonald-McGinn, D. M., Zackai, E. H., Lammer, E. J., Aylsworth, A. S., Ardinger, H. H., Lidral, A. C., Pober, B. R., Moreno, L., Arcos-Burgos, M., Valencia, C., Houdayer, C., Bahuau, M., Moretti-Ferreira, D., Richieri-Costa, A., Dixon, M. J., and Murray, J. C. (2002) Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat. Genet. 32, 285-289
-
(2002)
Nat. Genet.
, vol.32
, pp. 285-289
-
-
Kondo, S.1
Schutte, B.C.2
Richardson, R.J.3
Bjork, B.C.4
Knight, A.S.5
Watanabe, Y.6
Howard, E.7
De Lima, R.L.8
Daack-Hirsch, S.9
Sander, A.10
McDonald-McGinn, D.M.11
Zackai, E.H.12
Lammer, E.J.13
Aylsworth, A.S.14
Ardinger, H.H.15
Lidral, A.C.16
Pober, B.R.17
Moreno, L.18
Arcos-Burgos, M.19
Valencia, C.20
Houdayer, C.21
Bahuau, M.22
Moretti-Ferreira, D.23
Richieri-Costa, A.24
Dixon, M.J.25
Murray, J.C.26
more..
-
18
-
-
0014248101
-
Popliteal pterygium syndrome: A syndrome comprising cleft lip-palate, popliteal and intercrural pterygia, digital and genital anomalies
-
Gorlin, R. J., Sedano, H. O., and Cervenka, J. (1968) Popliteal pterygium syndrome: a syndrome comprising cleft lip-palate, popliteal and intercrural pterygia, digital and genital anomalies. Pediatrics 41, 503-509
-
(1968)
Pediatrics
, vol.41
, pp. 503-509
-
-
Gorlin, R.J.1
Sedano, H.O.2
Cervenka, J.3
-
19
-
-
84855839197
-
Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus
-
Mitchell, K., O'Sullivan, J., Missero, C., Blair, E., Richardson, R., Anderson, B., Antonini, D., Murray, J. C., Shanske, A. L., Schutte, B. C., Romano, R. A., Sinha, S., Bhaskar, S. S., Black, G. C., Dixon, J., and Dixon, M. J. (2012) Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus. Am. J. Hum. Genet. 90, 69-75
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 69-75
-
-
Mitchell, K.1
O'Sullivan, J.2
Missero, C.3
Blair, E.4
Richardson, R.5
Anderson, B.6
Antonini, D.7
Murray, J.C.8
Shanske, A.L.9
Schutte, B.C.10
Romano, R.A.11
Sinha, S.12
Bhaskar, S.S.13
Black, G.C.14
Dixon, J.15
Dixon, M.J.16
-
20
-
-
84855830157
-
Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome
-
Kalay, E., Sezgin, O., Chellappa, V., Mutlu, M., Morsy, H., Kayserili, H., Kreiger, E., Cansu, A., Toraman, B., Abdalla, E. M., Aslan, Y., Pillai, S., and Akarsu, N. A. (2012) Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome. Am. J. Hum. Genet. 90, 76-85
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 76-85
-
-
Kalay, E.1
Sezgin, O.2
Chellappa, V.3
Mutlu, M.4
Morsy, H.5
Kayserili, H.6
Kreiger, E.7
Cansu, A.8
Toraman, B.9
Abdalla, E.M.10
Aslan, Y.11
Pillai, S.12
Akarsu, N.A.13
-
21
-
-
0015357377
-
Popliteal pterygium syndrome: Evidence for a severe autosomal recessive form
-
Bartsocas, C. S., and Papas, C. V. (1972) Popliteal pterygium syndrome: evidence for a severe autosomal recessive form. J. Med. Genet. 9, 222-226
-
(1972)
J. Med. Genet.
, vol.9
, pp. 222-226
-
-
Bartsocas, C.S.1
Papas, C.V.2
-
22
-
-
0028020019
-
Bartsocas-Papas syndrome with internal anomalies: Evidence for a more generalized epithelial defect or new syndrome?
-
Hennekam, R. C., Huber, J., and Variend, D. (1994) Bartsocas-Papas syndrome with internal anomalies: evidence for a more generalized epithelial defect or new syndrome? Am. J. Med. Genet. 53, 102-107
-
(1994)
Am. J. Med. Genet.
, vol.53
, pp. 102-107
-
-
Hennekam, R.C.1
Huber, J.2
Variend, D.3
-
23
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma
-
Stransky, N., Egloff, A. M., Tward, A. D., Kostic, A. D., Cibulskis, K., Sivachenko, A., Kryukov, G. V., Lawrence, M. S., Sougnez, C., McKenna, A., Shefler, E., Ramos, A. H., Stojanov, P., Carter, S. L., Voet, D., Cortés, M. L., Auclair, D., Berger, M. F., Saksena, G., Guiducci, C., Onofrio, R. C., Parkin, M., Romkes, M., Weissfeld, J. L., Seethala, R. R., Wang, L., Rangel-Escareño, C., Fernandez-Lopez, J. C., Hidalgo-Miranda, A., Melendez-Zajgla, J., Winckler, W., Ardlie, K., Gabriel, S. B., Meyerson, M., Lander, E. S., Getz, G., Golub, T. R., Garraway, L. A., and Grandis, J. R. (2011) The mutational landscape of head and neck squamous cell carcinoma. Science 333, 1157-1160
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
Kostic, A.D.4
Cibulskis, K.5
Sivachenko, A.6
Kryukov, G.V.7
Lawrence, M.S.8
Sougnez, C.9
McKenna, A.10
Shefler, E.11
Ramos, A.H.12
Stojanov, P.13
Carter, S.L.14
Voet, D.15
Cortés, M.L.16
Auclair, D.17
Berger, M.F.18
Saksena, G.19
Guiducci, C.20
Onofrio, R.C.21
Parkin, M.22
Romkes, M.23
Weissfeld, J.L.24
Seethala, R.R.25
Wang, L.26
Rangel-Escareño, C.27
Fernandez-Lopez, J.C.28
Hidalgo-Miranda, A.29
Melendez-Zajgla, J.30
Winckler, W.31
Ardlie, K.32
Gabriel, S.B.33
Meyerson, M.34
Lander, E.S.35
Getz, G.36
Golub, T.R.37
Garraway, L.A.38
Grandis, J.R.39
more..
-
24
-
-
84904157420
-
Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells
-
Kwa, M. Q., Nguyen, T., Huynh, J., Ramnath, D., De Nardo, D., Lam, P. Y., Reynolds, E. C., Hamilton, J. A., Sweet, M. J., and Scholz, G. M. (2014) Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells. J. Biol. Chem. 289, 19758-19768
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 19758-19768
-
-
Kwa, M.Q.1
Nguyen, T.2
Huynh, J.3
Ramnath, D.4
De Nardo, D.5
Lam, P.Y.6
Reynolds, E.C.7
Hamilton, J.A.8
Sweet, M.J.9
Scholz, G.M.10
-
25
-
-
0033979731
-
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
-
Dickson, M. A., Hahn, W. C., Ino, Y., Ronfard, V., Wu, J. Y., Weinberg, R. A., Louis, D. N., Li, F. P., and Rheinwald, J. G. (2000) Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol. Cell Biol. 20, 1436-1447
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1436-1447
-
-
Dickson, M.A.1
Hahn, W.C.2
Ino, Y.3
Ronfard, V.4
Wu, J.Y.5
Weinberg, R.A.6
Louis, D.N.7
Li, F.P.8
Rheinwald, J.G.9
-
26
-
-
0028168798
-
Three NF-κ B binding sites in the human E-selectin gene required for maximal tumor necrosis factor κ-induced expression
-
Schindler, U., and Baichwal, V. R. (1994) Three NF-κ B binding sites in the human E-selectin gene required for maximal tumor necrosis factor κ-induced expression. Mol. Cell Biol. 14, 5820-5831
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 5820-5831
-
-
Schindler, U.1
Baichwal, V.R.2
-
27
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. e45
-
-
Pfaffl, M.W.1
-
28
-
-
42649114059
-
The IRF family transcription factors in immunity and oncogenesis
-
Tamura, T., Yanai, H., Savitsky, D., and Taniguchi, T. (2008) The IRF family transcription factors in immunity and oncogenesis. Annu. Rev. Immunol. 26, 535-584
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 535-584
-
-
Tamura, T.1
Yanai, H.2
Savitsky, D.3
Taniguchi, T.4
-
29
-
-
1942438618
-
Epidermal keratinocytes: Regulation of multiple cell phenotypes by multiple protein kinase C isoforms
-
Denning, M. F. (2004) Epidermal keratinocytes: regulation of multiple cell phenotypes by multiple protein kinase C isoforms. Int. J. Biochem. Cell Biol. 36, 1141-1146
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 1141-1146
-
-
Denning, M.F.1
-
30
-
-
44049111287
-
Protein kinase C in normal human epidermal keratinocytes during proliferation and calcium-induced differentiation
-
Matsui, M. S., Chew, S. L., and DeLeo, V. A. (1992) Protein kinase C in normal human epidermal keratinocytes during proliferation and calcium-induced differentiation. J. Invest. Dermatol. 99, 565-571
-
(1992)
J. Invest. Dermatol.
, vol.99
, pp. 565-571
-
-
Matsui, M.S.1
Chew, S.L.2
DeLeo, V.A.3
-
31
-
-
0028231262
-
Protein kinase C regulates keratinocyte transglutaminase (TGK) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium
-
Długosz, A. A., and Yuspa, S. H. (1994) Protein kinase C regulates keratinocyte transglutaminase (TGK) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium. J. Invest. Dermatol. 102, 409-414
-
(1994)
J. Invest. Dermatol.
, vol.102
, pp. 409-414
-
-
Długosz, A.A.1
Yuspa, S.H.2
-
32
-
-
3042644527
-
Regulation of involucrin gene expression
-
Eckert, R. L., Crish, J. F., Efimova, T., Dashti, S. R., Deucher, A., Bone, F., Adhikary, G., Huang, G., Gopalakrishnan, R., and Balasubramanian, S. (2004) Regulation of involucrin gene expression. J. Invest. Dermatol. 123, 13-22
-
(2004)
J. Invest. Dermatol.
, vol.123
, pp. 13-22
-
-
Eckert, R.L.1
Crish, J.F.2
Efimova, T.3
Dashti, S.R.4
Deucher, A.5
Bone, F.6
Adhikary, G.7
Huang, G.8
Gopalakrishnan, R.9
Balasubramanian, S.10
-
33
-
-
80051683924
-
Protein kinase C (PKC) δ suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism
-
Chew, Y. C., Adhikary, G., Wilson, G. M., Reece, E. A., and Eckert, R. L. (2011) Protein kinase C (PKC) δ suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism. J. Biol. Chem. 286, 28772-28782
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28772-28782
-
-
Chew, Y.C.1
Adhikary, G.2
Wilson, G.M.3
Reece, E.A.4
Eckert, R.L.5
-
34
-
-
0024948052
-
Terminal differentiation of epidermal keratinocytes
-
Watt, F. M. (1989) Terminal differentiation of epidermal keratinocytes. Curr. Opin. Cell Biol. 1, 1107-1115
-
(1989)
Curr. Opin. Cell Biol.
, vol.1
, pp. 1107-1115
-
-
Watt, F.M.1
-
35
-
-
0020572528
-
Involucrin and other markers of keratinocyte terminal differentiation
-
Watt, F. M. (1983) Involucrin and other markers of keratinocyte terminal differentiation. J. Invest. Dermatol. 81, 100s-103s
-
(1983)
J. Invest. Dermatol.
, vol.81
, pp. 100s-103s
-
-
Watt, F.M.1
-
36
-
-
0023809646
-
Keratins as biochemical markers of epithelial differentiation
-
Fuchs, E. (1988) Keratins as biochemical markers of epithelial differentiation. Trends Genet. 4, 277-281
-
(1988)
Trends Genet.
, vol.4
, pp. 277-281
-
-
Fuchs, E.1
-
37
-
-
20244389223
-
A homolog of Drosophila grainy head is essential for epidermal integrity in mice
-
Ting, S. B., Caddy, J., Hislop, N., Wilanowski, T., Auden, A., Zhao, L. L., Ellis, S., Kaur, P., Uchida, Y., Holleran, W. M., Elias, P. M., Cunningham, J. M., and Jane, S. M. (2005) A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science 308, 411-413
-
(2005)
Science
, vol.308
, pp. 411-413
-
-
Ting, S.B.1
Caddy, J.2
Hislop, N.3
Wilanowski, T.4
Auden, A.5
Zhao, L.L.6
Ellis, S.7
Kaur, P.8
Uchida, Y.9
Holleran, W.M.10
Elias, P.M.11
Cunningham, J.M.12
Jane, S.M.13
-
38
-
-
33749524559
-
The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4
-
Yu, Z., Lin, K. K., Bhandari, A., Spencer, J. A., Xu, X., Wang, N., Lu, Z., Gill, G. N., Roop, D. R., Wertz, P., and Andersen, B. (2006) The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev. Biol. 299, 122-136
-
(2006)
Dev. Biol.
, vol.299
, pp. 122-136
-
-
Yu, Z.1
Lin, K.K.2
Bhandari, A.3
Spencer, J.A.4
Xu, X.5
Wang, N.6
Lu, Z.7
Gill, G.N.8
Roop, D.R.9
Wertz, P.10
Andersen, B.11
-
39
-
-
84864585165
-
GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program
-
Hopkin, A. S., Gordon, W., Klein, R. H., Espitia, F., Daily, K., Zeller, M., Baldi, P., and Andersen, B. (2012) GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program. PLoS Genet. 8, e1002829
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002829
-
-
Hopkin, A.S.1
Gordon, W.2
Klein, R.H.3
Espitia, F.4
Daily, K.5
Zeller, M.6
Baldi, P.7
Andersen, B.8
-
40
-
-
33646076202
-
Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription
-
Nair, M., Teng, A., Bilanchone, V., Agrawal, A., Li, B., and Dai, X. (2006) Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. J. Cell Biol. 173, 253-264
-
(2006)
J. Cell Biol.
, vol.173
, pp. 253-264
-
-
Nair, M.1
Teng, A.2
Bilanchone, V.3
Agrawal, A.4
Li, B.5
Dai, X.6
-
41
-
-
33845655378
-
Strain-dependent perinatal lethality of Ovol1-deficient mice and identification of Ovol2 as a downstream target of Ovol1 in skin epidermis
-
Teng, A., Nair, M., Wells, J., Segre, J. A., and Dai, X. (2007) Strain-dependent perinatal lethality of Ovol1-deficient mice and identification of Ovol2 as a downstream target of Ovol1 in skin epidermis. Biochim. Biophys. Acta 1772, 89-95
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 89-95
-
-
Teng, A.1
Nair, M.2
Wells, J.3
Segre, J.A.4
Dai, X.5
-
42
-
-
0035829654
-
The Mad1 transcription factor is a novel target of activin and TGF-β action in keratinocytes: Possible role of Mad1 in wound repair and psoriasis
-
Werner, S., Beer, H. D., Mauch, C., Lüscher, B., and Werner, S. (2001) The Mad1 transcription factor is a novel target of activin and TGF-β action in keratinocytes: possible role of Mad1 in wound repair and psoriasis. Oncogene 20, 7494-7504
-
(2001)
Oncogene
, vol.20
, pp. 7494-7504
-
-
Werner, S.1
Beer, H.D.2
Mauch, C.3
Lüscher, B.4
Werner, S.5
-
43
-
-
84860258657
-
MAD1 and its life as a MYC antagonist: An update
-
Lüscher, B. (2012) MAD1 and its life as a MYC antagonist: an update. Eur J. Cell Biol. 91, 506-514
-
(2012)
Eur J. Cell Biol.
, vol.91
, pp. 506-514
-
-
Lüscher, B.1
-
44
-
-
39749124274
-
MYC in mammalian epidermis: How can an oncogene stimulate differentiation?
-
Watt, F. M., Frye, M., and Benitah, S. A. (2008) MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat. Rev. Cancer 8, 234-242
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 234-242
-
-
Watt, F.M.1
Frye, M.2
Benitah, S.A.3
-
45
-
-
0037053308
-
Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)α and PKCδ
-
Deucher, A., Efimova, T., and Eckert, R. L. (2002) Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)α and PKCδ. J. Biol. Chem. 277, 17032-17040
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17032-17040
-
-
Deucher, A.1
Efimova, T.2
Eckert, R.L.3
-
46
-
-
77954758155
-
PKC-δ and -η, MEKK-1, MEK-6, MEK-3, and p38-δ are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents
-
Adhikary, G., Chew, Y. C., Reece, E. A., and Eckert, R. L. (2010) PKC-δ and -η, MEKK-1, MEK-6, MEK-3, and p38-δ are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents. J. Invest. Dermatol. 130, 2017-2030
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 2017-2030
-
-
Adhikary, G.1
Chew, Y.C.2
Reece, E.A.3
Eckert, R.L.4
-
47
-
-
84879061732
-
Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes
-
Chew, Y. C., Adhikary, G., Xu, W., Wilson, G. M., and Eckert, R. L. (2013) Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes. J. Biol. Chem. 288, 17759-17768
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 17759-17768
-
-
Chew, Y.C.1
Adhikary, G.2
Xu, W.3
Wilson, G.M.4
Eckert, R.L.5
-
48
-
-
0032498962
-
Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis
-
Bushdid, P. B., Brantley, D. M., Yull, F. E., Blaeuer, G. L., Hoffman, L. H., Niswander, L., and Kerr, L. D. (1998) Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. Nature 392, 615-618
-
(1998)
Nature
, vol.392
, pp. 615-618
-
-
Bushdid, P.B.1
Brantley, D.M.2
Yull, F.E.3
Blaeuer, G.L.4
Hoffman, L.H.5
Niswander, L.6
Kerr, L.D.7
-
49
-
-
0032499286
-
Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb
-
Kanegae, Y., Tavares, A. T., Izpisúa Belmonte, J. C., and Verma, I. M. (1998) Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb. Nature 392, 611-614
-
(1998)
Nature
, vol.392
, pp. 611-614
-
-
Kanegae, Y.1
Tavares, A.T.2
Izpisúa Belmonte, J.C.3
Verma, I.M.4
-
50
-
-
2942716835
-
The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms
-
Gugasyan, R., Voss, A., Varigos, G., Thomas, T., Grumont, R. J., Kaur, P., Grigoriadis, G., and Gerondakis, S. (2004) The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms. Mol. Cell Biol. 24, 5733-5745
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 5733-5745
-
-
Gugasyan, R.1
Voss, A.2
Varigos, G.3
Thomas, T.4
Grumont, R.J.5
Kaur, P.6
Grigoriadis, G.7
Gerondakis, S.8
-
51
-
-
34547930163
-
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
-
Panne, D., McWhirter, S. M., Maniatis, T., and Harrison, S. C. (2007) Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J. Biol. Chem. 282, 22816-22822
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 22816-22822
-
-
Panne, D.1
McWhirter, S.M.2
Maniatis, T.3
Harrison, S.C.4
-
52
-
-
77956101874
-
Two missense mutations of the IRF6 gene in two Japanese families with popliteal pterygium syndrome
-
Matsuzawa, N., Kondo, S., Shimozato, K., Nagao, T., Nakano, M., Tsuda, M., Hirano, A., Niikawa, N., and Yoshiura, K. (2010) Two missense mutations of the IRF6 gene in two Japanese families with popliteal pterygium syndrome. Am. J. Med. Genet. A 152A, 2262-2267
-
(2010)
Am. J. Med. Genet. A
, vol.152 A
, pp. 2262-2267
-
-
Matsuzawa, N.1
Kondo, S.2
Shimozato, K.3
Nagao, T.4
Nakano, M.5
Tsuda, M.6
Hirano, A.7
Niikawa, N.8
Yoshiura, K.9
-
53
-
-
14744299357
-
The RIP kinases: Crucial integrators of cellular stress
-
Meylan, E., and Tschopp, J. (2005) The RIP kinases: crucial integrators of cellular stress. Trends Biochem. Sci. 30, 151-159
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 151-159
-
-
Meylan, E.1
Tschopp, J.2
-
54
-
-
81255210846
-
IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes
-
Restivo, G., Nguyen, B. C., Dziunycz, P., Ristorcelli, E., Ryan, R. J., Özuysal, Ö. Y., Di Piazza, M., Radtke, F., Dixon, M. J., Hofbauer, G. F., Lefort, K., and Dotto, G. P. (2011) IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 30, 4571-4585
-
(2011)
EMBO J.
, vol.30
, pp. 4571-4585
-
-
Restivo, G.1
Nguyen, B.C.2
Dziunycz, P.3
Ristorcelli, E.4
Ryan, R.J.5
Özuysal, O.Y.6
Di Piazza, M.7
Radtke, F.8
Dixon, M.J.9
Hofbauer, G.F.10
Lefort, K.11
Dotto, G.P.12
-
55
-
-
77951849894
-
Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice
-
Thomason, H. A., Zhou, H., Kouwenhoven, E. N., Dotto, G. P., Restivo, G., Nguyen, B. C., Little, H., Dixon, M. J., van Bokhoven, H., and Dixon, J. (2010) Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice. J. Clin. Invest. 120, 1561-1569
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1561-1569
-
-
Thomason, H.A.1
Zhou, H.2
Kouwenhoven, E.N.3
Dotto, G.P.4
Restivo, G.5
Nguyen, B.C.6
Little, H.7
Dixon, M.J.8
Van Bokhoven, H.9
Dixon, J.10
-
56
-
-
55049105999
-
Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip
-
Rahimov, F., Marazita, M. L., Visel, A., Cooper, M. E., Hitchler, M. J., Rubini, M., Domann, F. E., Govil, M., Christensen, K., Bille, C., Melbye, M., Jugessur, A., Lie, R. T., Wilcox, A. J., Fitzpatrick, D. R., Green, E. D., Mossey, P. A., Little, J., Steegers-Theunissen, R. P., Pennacchio, L. A., Schutte, B. C., and Murray, J. C. (2008) Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip. Nat. Genet. 40, 1341-1347
-
(2008)
Nat. Genet.
, vol.40
, pp. 1341-1347
-
-
Rahimov, F.1
Marazita, M.L.2
Visel, A.3
Cooper, M.E.4
Hitchler, M.J.5
Rubini, M.6
Domann, F.E.7
Govil, M.8
Christensen, K.9
Bille, C.10
Melbye, M.11
Jugessur, A.12
Lie, R.T.13
Wilcox, A.J.14
Fitzpatrick, D.R.15
Green, E.D.16
Mossey, P.A.17
Little, J.18
Steegers-Theunissen, R.P.19
Pennacchio, L.A.20
Schutte, B.C.21
Murray, J.C.22
more..
|