A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors

Investigational New Drugs

Volumn 33, Issue 3, 2015, Pages 603-610

  Chu, Quincy Siu Chung ^a   Sangha, Randeep ^a   Spratlin, Jennifer ^a   Vos, Larissa J ^a   Mackey, John R ^a   McEwan, Alexander J B ^a   Venner, Peter ^a   Michelakis, Evangelos D ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cancer; Dichloroacetate; Phase 1; Recommended phase 2 dose

Indexed keywords

ANTINEOPLASTIC AGENT; DICHLOROACETIC ACID;

ADULT; AGED; CANCER STAGING; CLINICAL TRIAL; COHORT ANALYSIS; DOSE RESPONSE; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; NEOPLASMS; PATHOLOGY; PHASE 1 CLINICAL TRIAL;

ADULT; AGED; ANTINEOPLASTIC AGENTS; COHORT STUDIES; DICHLOROACETIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; NEOPLASMS;

EID: 84939994601     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-015-0221-y     Document Type: Article

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