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Volumn 17, Issue 2, 2015, Pages 160-166

Final results of a phase II study of paclitaxel, bevacizumab, and gemcitabine as first-line therapy for patients with HER2-negative metastatic breast cancer

(16)  Salvador, J a   Manso, L b   de la Haba, J c   Jaen, A d   Ciruelos, E b   de Villena, M C e   Gil, M f   Murias, A g   Galan, A h   Jara, C i   Bayo, J j   Baena, J M k   Casal, J l   Mel, J R m   Blancas, I n   Sanchez Rvira, P d  


Author keywords

Bevacizumab; Gemcitabine; Metastatic breast cancer; Paclitaxel

Indexed keywords

AGTR1 PROTEIN, HUMAN; ANGIOTENSIN 1 RECEPTOR; ANTINEOPLASTIC AGENT; BEVACIZUMAB; DEOXYCYTIDINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEMCITABINE; MONOCLONAL ANTIBODY; PACLITAXEL;

EID: 84939880649     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-014-1210-x     Document Type: Article
Times cited : (10)

References (20)
  • 2
    • 41549131651 scopus 로고    scopus 로고
    • Bertuccio P, Levi F, Lucchini F, Negri E, La Vecchia C. Cancer mortality in the European Union, 1970–2003, with a joinpoint analysis. Ann Oncol. 2008;
    • Bosetti C, Bertuccio P, Levi F, Lucchini F, Negri E, La Vecchia C. Cancer mortality in the European Union, 1970–2003, with a joinpoint analysis. Ann Oncol. 2008; 19(4):631–40. Epub 2008 Feb 14.
    • (2008) Ann Oncol. , vol.19 , Issue.4 , pp. 631-640
  • 3
    • 77954335786 scopus 로고    scopus 로고
    • Locally recurrent or metastatic breast cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • PID: 20555067
    • Cardoso F, Senkus-Konefka E, Fallowfield L, Costa A, Castiglione M. Locally recurrent or metastatic breast cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010;21(suppl 5):v15–9.
    • (2010) Ann Oncol , vol.21 , pp. v15-v19
    • Cardoso, F.1    Senkus-Konefka, E.2    Fallowfield, L.3    Costa, A.4    Castiglione, M.5
  • 4
    • 0037445132 scopus 로고    scopus 로고
    • Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer
    • COI: 1:CAS:528:DC%2BD2cXpsVGqs7c%3D, PID: 12637460
    • Henderson IC, Berry DA, Demetri GD, Cirrincione CT, Goldstein LJ, Martino S, et al. Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol. 2003;21(6):976–83.
    • (2003) J Clin Oncol , vol.21 , Issue.6 , pp. 976-983
    • Henderson, I.C.1    Berry, D.A.2    Demetri, G.D.3    Cirrincione, C.T.4    Goldstein, L.J.5    Martino, S.6
  • 5
    • 1642396334 scopus 로고    scopus 로고
    • Gemcitabine plus paclitaxel administered as firstline chemotherapy for patients with advanced breast cancer (ABC)
    • Delfino C, Caccia GM, Riva Gonzales L, Mickiewicz E.: Gemcitabine plus paclitaxel administered as firstline chemotherapy for patients with advanced breast cancer (ABC). Proc Am Soc Clin Oncol. 2002;21:53b (abstr 2025).
    • (2002) Proc Am Soc Clin Oncol , vol.53b , Issue.abstr 2025 , pp. 21
    • Delfino, C.1    Caccia, G.M.2    Riva Gonzales, L.3    Mickiewicz, E.4
  • 6
    • 0034984359 scopus 로고    scopus 로고
    • Phase II trial of the use of paclitaxel and gemcitabine as a salvage treatment in metastatic breast cancer
    • COI: 1:STN:280:DC%2BD3MzjsFenuw%3D%3D, PID: 11404498
    • Murad AM, Guimaraes RC, Aragao BC, Scalabrini-Neto AO, Rodrigues VH, Garcia R. Phase II trial of the use of paclitaxel and gemcitabine as a salvage treatment in metastatic breast cancer. Am J Clin Oncol. 2001;24:264–8.
    • (2001) Am J Clin Oncol , vol.24 , pp. 264-268
    • Murad, A.M.1    Guimaraes, R.C.2    Aragao, B.C.3    Scalabrini-Neto, A.O.4    Rodrigues, V.H.5    Garcia, R.6
  • 7
    • 24944535246 scopus 로고    scopus 로고
    • Phase II study of gemcitabine plus paclitaxel in metastatic breast cancer patients with prior anthracycline exposure
    • COI: 1:CAS:528:DC%2BD2MXhtFWjtrvF, PID: 16193637
    • Demiray M, Kurt E, Evrensel T, Kanat O, Arslan M, Saraydaroglu O, et al. Phase II study of gemcitabine plus paclitaxel in metastatic breast cancer patients with prior anthracycline exposure. Cancer Invest. 2005;23:386–91.
    • (2005) Cancer Invest , vol.23 , pp. 386-391
    • Demiray, M.1    Kurt, E.2    Evrensel, T.3    Kanat, O.4    Arslan, M.5    Saraydaroglu, O.6
  • 8
    • 50549096593 scopus 로고    scopus 로고
    • Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
    • PID: 18711184
    • Albain KS, Nag SM, Calderillo-Ruiz G, Jordaan JP, Llombart AC, Pluzanska A, et al. Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment. J Clin Oncol. 2008;26(24):3950–7.
    • (2008) J Clin Oncol , vol.26 , Issue.24 , pp. 3950-3957
    • Albain, K.S.1    Nag, S.M.2    Calderillo-Ruiz, G.3    Jordaan, J.P.4    Llombart, A.C.5    Pluzanska, A.6
  • 9
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible of angiogenesis
    • Folkman J, Merler E, Abernathy C, Williams G. Isolation of a tumor factor responsible of angiogenesis. J Exp Med. 1971;133(2):276–88
    • (1971) J Exp Med , vol.133 , Issue.2 , pp. 276-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 10
    • 77955883504 scopus 로고    scopus 로고
    • A meta-analysis of overall survival data from three randomized trials of bevacizumab (BV) and first-line chemotherapy as treatment for patients with metastatic breast cancer (MBC)
    • O’Shaughnessy J, Miles D, Gray R, Dieras V, Perez E, Zon R, et al. A meta-analysis of overall survival data from three randomized trials of bevacizumab (BV) and first-line chemotherapy as treatment for patients with metastatic breast cancer (MBC). Proc Am Soc Clin Oncol 2010;28(suppl):abstr 1005.
    • Proc Am Soc Clin Oncol 2010;28(suppl):abstr
    • O’Shaughnessy, J.1    Miles, D.2    Gray, R.3    Dieras, V.4    Perez, E.5    Zon, R.6
  • 11
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • COI: 1:CAS:528:DC%2BD1cXisVOnsg%3D%3D, PID: 18160686
    • Miller K, Wang M, Gralow J, Dickler M, Cobleigh M, Perez EA. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med. 2007;357:2666–76.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3    Dickler, M.4    Cobleigh, M.5    Perez, E.A.6
  • 12
    • 84939915633 scopus 로고    scopus 로고
    • Zielinski C, Lang I, Inbar M, Kahan Z, Greil R, Beslija S, et al. First efficacy results from the TURANDOT phase III trial comparing two bevacizumab containing regimens as first line therapy for HER-2 negative metastatic breast cancer. Annals of Oncology 2012;23(supplement 9) abstract 3170
    • Zielinski C, Lang I, Inbar M, Kahan Z, Greil R, Beslija S, et al. First efficacy results from the TURANDOT phase III trial comparing two bevacizumab containing regimens as first line therapy for HER-2 negative metastatic breast cancer. Annals of Oncology 2012;23(supplement 9) abstract 3170.
  • 13
    • 77956132705 scopus 로고    scopus 로고
    • Clinical value of circulating endothelial cells and circulating tumor cells in metastatic breast cancer patients treated first line with bevacizumab and chemotherapy
    • PID: 20233745, Epub 2010 Mar 16
    • Bidard FC, Mathiot C, Degeorges A, Etienne-Grimaldi MC, Delva R, Pivot X, et al. Clinical value of circulating endothelial cells and circulating tumor cells in metastatic breast cancer patients treated first line with bevacizumab and chemotherapy. Ann Oncol. 2010;21(9):1765–71. Epub 2010 Mar 16.
    • (2010) Ann Oncol , vol.21 , Issue.9 , pp. 1765-1771
    • Bidard, F.C.1    Mathiot, C.2    Degeorges, A.3    Etienne-Grimaldi, M.C.4    Delva, R.5    Pivot, X.6
  • 14
    • 84939915634 scopus 로고    scopus 로고
    • Sanchez-Rovira P, de la Haba-Rodriguez J, Fernandez-Navarro M, Segui M, Llombart-Cussac A, Anton A, et al. Predictive response factors in an open non- randomized phase II study of a combination of bevacizumab and sequential chemotherapy as preoperative treatment in patients with operable Her-2 negative breast cancer. J Clin Oncol 2010;28:(suppl; abstr 556)
    • Sanchez-Rovira P, de la Haba-Rodriguez J, Fernandez-Navarro M, Segui M, Llombart-Cussac A, Anton A, et al. Predictive response factors in an open non- randomized phase II study of a combination of bevacizumab and sequential chemotherapy as preoperative treatment in patients with operable Her-2 negative breast cancer. J Clin Oncol 2010;28:(suppl; abstr 556).
  • 15
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • COI: 1:STN:280:DC%2BD3c7it1Gitg%3D%3D, PID: 10655437
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000;92:205–16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 16
    • 71549143528 scopus 로고    scopus 로고
    • Detecting an overall survival benefit that is derived from progression-free survival
    • PID: 19903805
    • Broglio KR, Berry DA. Detecting an overall survival benefit that is derived from progression-free survival. J Natl Cancer Inst. 2009;101:1642–9.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1642-1649
    • Broglio, K.R.1    Berry, D.A.2
  • 17
    • 77951642723 scopus 로고    scopus 로고
    • Overall survival and post-progression survival in advanced breast cancer: a review of recent randomized clinical trials
    • PID: 20194852
    • Saad ED, Katz A, Buyse M. Overall survival and post-progression survival in advanced breast cancer: a review of recent randomized clinical trials. J Clin Oncol. 2010;28:1958–62.
    • (2010) J Clin Oncol , vol.28 , pp. 1958-1962
    • Saad, E.D.1    Katz, A.2    Buyse, M.3
  • 18
    • 80052729506 scopus 로고    scopus 로고
    • A randomized phase II study of paclitaxel and bevacizumab with and without gemcitabine as first-line treatment for metastatic breast cancer
    • COI: 1:CAS:528:DC%2BC3MXhtlKisr%2FO, PID: 21723792, Epub 2011 Jul 1
    • Brufsky A, Hoelzer K, Beck T, Whorf R, Keaton M, Nadella P, et al. A randomized phase II study of paclitaxel and bevacizumab with and without gemcitabine as first-line treatment for metastatic breast cancer. Clin Breast Cancer. 2011;11(4):211–220. Epub 2011 Jul 1.
    • (2011) Clin Breast Cancer , vol.11 , Issue.4 , pp. 211-220
    • Brufsky, A.1    Hoelzer, K.2    Beck, T.3    Whorf, R.4    Keaton, M.5    Nadella, P.6
  • 19
    • 84939883689 scopus 로고    scopus 로고
    • Park JW. Change in circulating endothelial cells (CEC) predicts progression free survival (PFS) in patients (pts) with hormone receptor positive metastatic breast cancer (MBC) receiving letrozole (L) and bevacizumab (B). J Clin Oncol, 2006 ASCO Annual Meeting Proceedings Part I. Vol 24
    • Rugo H, Dickler M.N, Traina TA, Scott JH, Park JW. Change in circulating endothelial cells (CEC) predicts progression free survival (PFS) in patients (pts) with hormone receptor positive metastatic breast cancer (MBC) receiving letrozole (L) and bevacizumab (B). J Clin Oncol, 2006 ASCO Annual Meeting Proceedings Part I. Vol 24, No. 18S (June 20 Supplement), 2006: 3039.
    • (2006) No , vol.18S , pp. 3039
    • Rugo, H.1    Dickler, M.N.2    Traina, T.A.3    Scott, J.H.4
  • 20
    • 67649505084 scopus 로고    scopus 로고
    • AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist
    • COI: 1:CAS:528:DC%2BD1MXot1Cku7w%3D, PID: 19487683, Epub 2009 Jun 1
    • Rhodes DR, Ateeq B, Cao Q, Tomlins SA, Mehra R, Laxman B, et al. AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist. Proc Natl Acad Sci USA. 2009;106(25):10284–9. Epub 2009 Jun 1.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.25 , pp. 10284-10289
    • Rhodes, D.R.1    Ateeq, B.2    Cao, Q.3    Tomlins, S.A.4    Mehra, R.5    Laxman, B.6


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