Effects of postprandial starvation on mRNA expression of endocrine-, amino acid and peptide transporter-, and metabolic enzyme-related genes in zebrafish (Danio rerio)

Fish Physiology and Biochemistry

Volumn 41, Issue 3, 2015, Pages 773-787

  Tian, Juan ^a,b   He, Gen ^a   Mai, Kangsen ^a   Liu, Chengdong ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE   (China)

Author keywords

Metabolic enzymes; Postprandial starvation; Transporters; Zebrafish

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINO ACID TRANSPORTER; ASPARTATE AMINOTRANSFERASE; CARRIER PROTEIN; CHOLECYSTOKININ; FATTY ACID SYNTHASE; GLUTAMATE AMMONIA LIGASE; GLUTAMATE DEHYDROGENASE; LEPTIN; LIPOPROTEIN LIPASE; MESSENGER RNA; NEUROPEPTIDE Y; PEPTIDE PERMEASE; PRIMER DNA; TRYPSIN;

ANALYSIS OF VARIANCE; ANIMAL; DIET RESTRICTION; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; POSTPRANDIAL STATE; REAL TIME POLYMERASE CHAIN REACTION; TIME FACTOR; ZEBRA FISH;

ALANINE TRANSAMINASE; AMINO ACID TRANSPORT SYSTEMS; ANALYSIS OF VARIANCE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CHOLECYSTOKININ; DNA PRIMERS; FASTING; FATTY ACID SYNTHASES; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; GLUTAMATE DEHYDROGENASE; GLUTAMATE-AMMONIA LIGASE; LEPTIN; LIPOPROTEIN LIPASE; MEMBRANE TRANSPORT PROTEINS; NEUROPEPTIDE Y; POSTPRANDIAL PERIOD; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRYPSIN; ZEBRAFISH;

EID: 84939965729     PISSN: 09201742     EISSN: 15735168     Source Type: Journal    
DOI: 10.1007/s10695-015-0045-x     Document Type: Article

References (112)

1. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS (1996) Role of leptin in the neuroendocrine response to fastings. Nature 382:250–252
2. Anemaet IG, Metón I, Salgado MC, Fernández F, Baanante IV (2008) A novel alternatively spliced transcript of cytosolic alanine aminotransferase gene associated with enhanced gluconeogenesis in liver of Sparus aurata. Int J Biochem Cell Biol 40:2833–2844
3. Ardawi M (1990) Glutamine-synthesizing activity in lungs of fed, starved, acidotic, diabetic, injured and septic rats. Biochem J 270:829–832
4. Arola L, Palou A, Remesar X, Alemany M (1981) Glutamine synthetase activity in the organs of fed and 24-hours fasted rats. Horm Metab Res 13:199–202
5. Association AVM (2013) AVMA guidelines for the euthanasia of animals, 2013th edn. AVMA, Schaumburg
6. Babichuk NA, Volkoff H (2013) Changes in expression of appetite-regulating hormones in the cunner (Tautogolabrus adspersus) during short-term fasting and winter torpor. Physiol Behav 120:54–63
7. Bar N, Volkoff H (2012) Adaptation of the physiological, endocrine, and digestive system functions to prolonged food deprivation in fish. In: Comparative Physiology of Fasting, Starvation, and Food Limitation, Springer, pp 69–89
8. Barclay M, Dall W, Smith D (1983) Changes in lipid and protein during starvation and the moulting cycle in the tiger prawn, Penaeus esculentus Haswell. J Exp Mar Biol Ecol 68:229–244
9. Blasco J, Fernández J, Gutiérrez J (1991) The effects of starvation and refeeding on plasma amino acid levels in carp, Cyprinus carpio L., 1758. J Fish Biol 38:587–598
10. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Biochem 55:611–622
11. Canosa LF, Unniappan S, Peter RE (2005) Periprandial changes in growth hormone release in goldfish: role of somatostatin, ghrelin, and gastrin-releasing peptide. Am J Physiol Regul Integr Comp Physiol 289:R125–R133
12. Canosa LF, Chang JP, Peter RE (2007) Neuroendocrine control of growth hormone in fish. Gen Comp Endocrinol 151:1–26
13. Carter C, Houlihan D, Kiessling A, Médale F, Jobling M (2007) Physiological effects of feeding. In: Food intake in fish, Blackwell Science Ltd., pp 297–331
14. Cerdá-Reverter JM, Anglade I, Martínez-Rodríguez G, Mazurais D, Muñoz-Cueto JA, Carrillo M, Kah O, Zanuy S (2000a) Characterization of Neuropeptide Y expression in the brain of a perciform fish, the sea bass (Dicentrarchus labrax). J Chem Neuroanat 19:197–210
15. Cerdá-Reverter JM, Martínez-Rodríguez G, Zanuy S, Carrillo M, Larhammar D (2000b) Molecular evolution of the Neuropeptide Y (NPY) family of peptides: cloning of three NPY-related peptides from the sea bass (Dicentrarchus labrax). Regul Pept 95:25–34
16. Chen M, Huang X, Yuen DS, Cheng CH (2011) A study on the functional interaction between the GH/PRL family of polypeptides with their receptors in zebrafish: evidence against GHR1 being the receptor for somatolactin. Mol Cell Endocrinol 337:114–121
17. Corà S (2011) Molecular cloning and expression analysis of genes involved in the compensatory growth of sea bass (Dicentrarchus labrax). Doctoral Thesis, Università degli Studi dell'Insubria
18. Davis KB, Gaylord TG (2011) Effect of fasting on body composition and responses to stress in sunshine bass. Comp Biochem Physiol A Mol Integr Physiol 158:30–36
19. Deng L, Zhang WM, Lin HR, Cheng CHK (2004) Effects of food deprivation on expression of growth hormone receptor and proximate composition in liver of black seabream Acanthopagrus schlegeli. Comp Biochem Physiol B Biochem Mol Biol 137:421–432
20. Dhanasiri AKS, Fernandes JMO, Kiron V (2012) Glutamine synthetase activity and the expression of three glul paralogues in zebrafish during transport. Comp Biochem Physiol B Biochem Mol Biol 163:274–284
21. Drew RE, Rodnick KJ, Settles M, Wacyk J, Churchill E, Powell MS, Hardy RW, Murdoch GK, Hill RA, Robison BD (2008) Effect of starvation on transcriptomes of brain and liver in adult female zebrafish (Danio rerio). Physiol Genomics 35:283–295
22. Enes P, Panserat S, Kaushik S, Oliva-Teles A (2009) Nutritional regulation of hepatic glucose metabolism in fish. Fish Physiol Biochem 35:519–539
23. Feng K, Zhang G-R, Wei K-J, Xiong B-X, Liang T, Ping H-C (2012) Molecular characterization of Cholecystokinin in grass carp (Ctenopharyngodon idellus): cloning, localization, developmental profile, and effect of fasting and refeeding on expression in the brain and intestine. Fish Physiol Biochem 38:1825–1834
24. Fox BK, Riley LG, Hirano T, Grau EG (2006) Effects of fasting on growth hormone, growth hormone receptor, and insulin-like growth factor-I axis in seawater-acclimated tilapia, Oreochromis mossambicus. Gen Comp Endocrinol 148:340–347
25. Fox BK, Breves JP, Hirano T, Grau EG (2009) Effects of short- and long-term fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus. Domest Anim Endocrinol 37:1–11
26. Francis D, Thanuthong T, Senadheera S, Paolucci M, Coccia E, De Silva S, Turchini G (2014) n-3 LC-PUFA deposition efficiency and appetite-regulating hormones are modulated by the dietary lipid source during rainbow trout grow-out and finishing periods. Fish Physiol Biochem 40:577–593
27. Fuentes EN, Valdés JA, Molina A, Björnsson BT (2013) Regulation of skeletal muscle growth in fish by the growth hormone–insulin-like growth factor system. Gen Comp Endocrinol 192:136–148
28. Fukada H, Ozaki Y, Pierce AL, Adachi S, Yamauchi K, Hara A, Swanson P, Dickhoff WW (2004) Salmon growth hormone receptor: molecular cloning, ligand specificity, and response to fasting. Gen Comp Endocrinol 139:61–71
29. Fukada H, Ozaki Y, Pierce AL, Adachi S, Yamauchi K, Hara A, Swanson P, Dickhoff WW (2005) Identification of the salmon somatolactin receptor, a new member of the cytokine receptor family. Endocrinology 146:2354–2361
30. Fukamachi S, Yada T, Mitani H (2005) Medaka receptors for somatolactin and growth hormone: phylogenetic paradox among fish growth hormone receptors. Genetics 171:1875–1883
31. Ganapathy ME, Prasad PD, Mackenzie B, Ganapathy V, Leibach FH (1997) Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2. Biochim Biophys Acta Biomembr 1324:296–308
32. Ganapathy ME, Huang W, Wang H, Ganapathy V, Leibach FH (1998) Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2. Biochem Biophys Res Commun 246:470–475
33. García-Garrido S, Hachero-Cruzado I, Rosas C, Domingues P (2013) Protein and amino acid composition from the mantle of juvenile Octopus vulgaris exposed to prolonged starvation. Aquac Res 44:1741–1751
34. George-Zamora A, Viana M-T, Rodríguez S, Espinoza G, Rosas C (2011) Amino acid mobilization and growth of juvenile Octopus maya (Mollusca: Cephalopoda) under inanition and re-feeding. Aquaculture 314:215–220
35. Gilbert ER, Wong EA, Webb KE (2008) Board-invited review: peptide absorption and utilization: implications for animal nutrition and health. J Anim Sci 86:2135–2155
36. Gómez-Requeni P, Conceição LEC, Olderbakk Jordal AE, Rønnestad I (2010) A reference growth curve for nutritional experiments in zebrafish (Danio rerio) and changes in whole body proteome during development. Fish Physiol Biochem 36:1199–1215
37. Gosmain Y, Dif N, Berbe V, Loizon E, Rieusset J, Vidal H, Lefai E (2005) Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues. J Lipid Res 46:697–705
38. Greenwood M (1984) The relationship of enzyme activity to feeding behavior in rats: lipoprotein lipase as the metabolic gatekeeper. Int J obes 9:67–70
39. Hanson RW, Reshef L (1997) Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu Rev Biochem 66:581–611
40. Hatch K (2012) The use and application of stable isotope analysis to the study of starvation, fasting, and nutritional stress in animals. In: McCue MD (ed) Comparative physiology of fasting, starvation, and food limitation. Springer, Berlin, Heidelberg, pp 337–364
41. Hayes J, Volkoff H (2014) Characterization of the endocrine, digestive and morphological adjustments of the intestine in response to food deprivation and torpor in cunner, Tautogolabrus adspersus. Comp Biochem Physiol A Mol Integr Physiol 170:46–59
42. Hevrøy EM, Azpeleta C, Shimizu M, Lanzén A, Kaiya H, Espe M, Olsvik PA (2011) Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon. Fish Physiol Biochem 37:217–232
43. Holzenberger M, Kappeler L, Magalhaes Filho C, Bouc Y (2005) The GH/IGF-1 axis: insights from animal models in deciphering growth. In: Carel J-C et al (eds) Springer, Berlin, Heidelberg, pp 41–51
44. Hundal HS, Taylor PM (2009) Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling. Am J Physiol Endocrinol Metab 296:E603–E613
45. Jönsson E, Forsman A, Einarsdottir IE, Kaiya H, Ruohonen K, Björnsson BT (2007) Plasma ghrelin levels in rainbow trout in response to fasting, feeding and food composition, and effects of ghrelin on voluntary food intake. Comp Biochem Physiol A Mol Integr Physiol 147:1116–1124
46. Kaiya H, Miyazato M, Kangawa K, Peter RE, Unniappan S (2008) Ghrelin: a multifunctional hormone in non-mammalian vertebrates. Comp Biochem Physiol A Mol Integr Physiol 149:109–128
47. Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS (1999) Interacting appetite-regulating pathways in the hypothalamic regulation of body weight 1. Endocr Rev 20:68–100
48. Kamijo M, Kojima K, Maruyama K, Konno N, Motohashi E, Ikegami T, Uchiyama M, Shioda S, Ando H, Matsuda K (2011) Neuropeptide Y in tiger puffer (Takifugu rubripes): distribution, cloning, characterization, and mRNA expression responses to prandial condition. Zool Sci 28:882–890
49. Kirchner S, Kaushik S, Panserat S (2003) Effect of partial substitution of dietary protein by a single gluconeogenic dispensable amino acid on hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol A Mol Integr Physiol 134:337–347
50. Kletzien RF, Harris PK, Foellmi LA (1994) Glucose-6-phosphate dehydrogenase: a “housekeeping” enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress. FASEB J 8:174–181
51. Kling P, Jönsson E, Nilsen TO, Einarsdottir IE, Rønnestad I, Stefansson SO, Björnsson BT (2012) The role of growth hormone in growth, lipid homeostasis, energy utilization and partitioning in rainbow trout: interactions with leptin, ghrelin and insulin-like growth factor I. Gen Comp Endocrinol 175:153–162
52. Klok MD, Jakobsdottir S, Drent ML (2007) The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. Obes Rev 8:21–34
53. Kong S-E, Hall JC, Cooper D, McCauley RD (2000) Starvation alters the activity and mRNA level of glutaminase and glutamine synthetase in the rat intestine. J Nutr Biochem 11:393–400
54. Koven W, Schulte P (2012) The effect of fasting and refeeding on mRNA expression of PepT1 and gastrointestinal hormones regulating digestion and food intake in zebrafish (Danio rerio). Fish Physiol Biochem 38:1565–1575
55. Labow BI, Souba WW, Abcouwer SF (1999) Glutamine synthetase expression in muscle is regulated by transcriptional and posttranscriptional mechanisms. Am J Physiol Endocrinol Metab 276:E1136–E1145
56. Li M, Li C, Allen A, Stanley C, Smith T (2014) Glutamate dehydrogenase: structure, allosteric regulation, and role in insulin homeostasis. Neurochem Res 39:433–445
57. Liang XF, Oku H, Ogata HY (2002) The effects of feeding condition and dietary lipid level on lipoprotein lipase gene expression in liver and visceral adipose tissue of red sea bream Pagrus major. Comp Biochem Physiol A Mol Integr Physiol 131:335–342
58. Liang X-F, Li G-Z, Yao W, Cheong L-W, Liao W-Q (2007) Molecular characterization of Neuropeptide Y gene in Chinese perch, an acanthomorph fish. Comp Biochem Physiol B Biochem Mol Biol 148:55–64
59. Liddle RA (1997) Cholecystokinin cells. Annu Rev Physiol 59:221–242
60. Lignot J-H, LeMaho Y (2012) A History of modern research into fasting, starvation, and inanition. In: comparative physiology of fasting, starvation, and food limitation, Springer, pp 7–23
61. −ΔΔCT method. Methods 25:402–408
62. Loughna PT, Goldspink G (1984) The effects of starvation upon protein turnover in red and white myotomal muscle of rainbow trout, Salmo gairdneri Richardson. J Fish Biol 25:223–230
63. Luzzatto L, Battistuzzi G (1985) Glucose-6-phosphate dehydrogenase. In: Harris H, Hirschhorn K (eds) Advances in human genetics 14. Springer, US, pp 217–329
64. Machado C, Garofaloj M, Roselino J, Kettelhut I, Migliorini R (1988) Effects of starvation, refeeding, and insulin on energy-linked metabolic processes in catfish (Rhamdia hilarii) adapted to a carbohydrate-rich diet. Gen Comp Endocrinol 71:429–437
65. Magnuson MA, Matschinsky FM (2004) Glucokinase as a glucose sensor: past, present and future. In: Matschinsky FM, Magnuson MA (eds) Glucokinase and glycemic disease: from basics to novel therapeutics. Krager, Basel, pp 1–17
66. Maures T, Chan SJ, Xu B, Sun H, Ding J, Duan C (2002) Structural, biochemical, and expression analysis of two distinct insulin-like growth factor I receptors and their ligands in zebrafish. Endocrinology 143:1858–1871
67. McCue MD (2006) Specific dynamic action: a century of investigation. Comp Biochem Physiol A Mol Integr Physiol 144:381–394
68. Metón I, Caseras A, Fernández F, Baanante IV (2004) Molecular cloning of hepatic glucose-6-phosphatase catalytic subunit from gilthead sea bream (Sparus aurata): response of its mRNA levels and glucokinase expression to refeeding and diet composition. Comp Biochem Physiol B Biochem Mol Biol 138:145–153
69. Mezzarobba V, Torrent A, Leydier I, Alles S, Brajon B, Mignon M, Attaix D, Meynial-Denis D (2003) The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats. Clin Nutr (Edinburgh, Scotland) 22:569–575
70. Murashita K, Kurokawa T, Ebbesson LOE, Stefansson SO, Rønnestad I (2009) Characterization, tissue distribution, and regulation of agouti-related protein (AgRP), cocaine- and amphetamine-regulated transcript (CART) and Neuropeptide Y (NPY) in Atlantic salmon (Salmo salar). Gen Comp Endocrinol 162:160–171
71. Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K, Matsukura S (2001) A role for ghrelin in the central regulation of feeding. Nature 409:194–198
72. Narnaware YK, Peter RE (2001) Effects of food deprivation and refeeding on Neuropeptide Y (NPY) mRNA levels in goldfish. Comp Biochem Physiol B Biochem Mol Biol 129:633–637
73. Palou M, Sanchez J, Priego T, Rodriguez AM, Pico C, Palou A (2010) Regional differences in the expression of genes involved in lipid metabolism in adipose tissue in response to short- and medium-term fasting and refeeding. J Nutr Biochem 21:23–33
74. Pankhurst NW, King H, Ludke S (2008) Relationship between stress, feeding and plasma ghrelin levels in rainbow trout, Oncorhynchus mykiss. Mar Freshw Behav Physiol 41:53–64
75. Panserat S, Plagnes-Juan E, Kaushik S (2001) Nutritional regulation and tissue specificity of gene expression for proteins involved in hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss). J Exp Biol 204:2351–2360
76. Picha ME, Strom CN, Riley LG, Walker AA, Won ET, Johnstone WM, Borski RJ (2009) Plasma ghrelin and growth hormone regulation in response to metabolic state in hybrid striped bass: effects of feeding, ghrelin and insulin-like growth factor-I on in vivo and in vitro GH secretion. Gen Comp Endocrinol 161:365–372
77. Poncet N, Taylor PM (2013) The role of amino acid transporters in nutrition. Curr Opin Clin Nutr Metab Care 16:57–65
78. Pontet A, Danger JM, Dubourg P, Pelletier G, Vaudry H, Calas A, Kah O (1989) Distribution and characterization of Neuropeptide Y-like immunoreactivity in the brain and pituitary of the goldfish. Cell Tissue Res 255:529–538
79. Preiss-Landl K, Zimmermann R, Hämmerle G, Zechner R (2002) Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr Opin Lipidol 13:471–481
80. Rehfeld JF (2004) Cholecystokinin. Best Pract Res Clin Endocrinol Metab 18:569–586
81. Reindl KM, Sheridan MA (2012) Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates. Comp Biochem Physiol A Mol Integr Physiol 163:231–245
82. Ribas L, Piferrer F (2014) The zebrafish (Danio rerio) as a model organism, with emphasis on applications for finfish aquaculture research. Rev Aquac 6:209–240
83. Riley LG, Fox BK, Breves JP, Kaiya H, Dorough CP, Hirano T, Grau EG (2008) Absence of effects of short-term fasting on plasma ghrelin and brain expression of ghrelin receptors in the tilapia, Oreochromis mossambicus. Zool Sci 25:821–827
84. Rodriguez J, Gupta N, Smith RD, Pevzner PA (2007) Does trypsin cut before proline? J Proteome Res 7:300–305
85. Romijn JA, Godfried MH, Hommes MJT, Endert E, Sauerwein HP (1990) Decreased glucose oxidation during short-term starvation. Metabolism 39:525–530
86. Rønnestad I, Murashita K, Kottra G, Jordal A-E, Narawane S, Jolly C, Daniel H, Verri T (2010) Molecular cloning and functional expression of atlantic salmon peptide transporter 1 in xenopus oocytes reveals efficient intestinal uptake of lysine-containing and other bioactive di- and tri-peptides in teleost fish. J Nutr 140:893–900
87. Rubio V, Sanchez-Vazquez F, Madrid J (2008) Role of Cholecystokinin and its antagonist proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L. Physiol Behav 93:862–869
88. Schneider A, Pfeifer LFM, da Silva Neto JW, Hax LT, Antunes MM, Del Pino FAB, Paludo GR, Corrêa MN (2011) Effect of exogenous insulin and fasting on growth hormone receptor and IGF-I expression in the pre-ovulatory follicle of ewes. Animal 5:1420–1425
89. Secor S (2009) Specific dynamic action: a review of the postprandial metabolic response. J Comp Physiol B 179:1–56
90. Seiliez I, Médale F, Aguirre P, Larquier M, Lanneretonne L, Alami-Durante H, Panserat S, Skiba-Cassy S (2013) Postprandial regulation of growth-and metabolism-related factors in zebrafish. Zebrafish 10:237–248
91. Shimizu S, Azuma M, Morimoto N, Kikuyama S, Matsuda K (2013) Effect of Neuropeptide Y on food intake in bullfrog larvae. Peptides 46:102–107
92. Silverstein JT, Plisetskaya EM (2000) The effects of NPY and insulin on food intake regulation in fish. Am Zool 40:296–308
93. Soengas JL, Polakof S, Chen X, Sangiao-Alvarellos S, Moon TW (2006) Glucokinase and hexokinase expression and activities in rainbow trout tissues: changes with food deprivation and refeeding. Am J Physiol Regul Integr Comp Physiol 291:R810–R821
94. Stieg MR, Sievers C, Farr O, Stalla GK, Mantzoros CS (2015) Leptin: a hormone linking activation of neuroendocrine axes with neuropathology. Psychoneuroendocrinology 51:47–57
95. Taylor PM (2014) Role of amino acid transporters in amino acid sensing. Am J Clin Nutr 99:223S–230S
96. Terova G, Corà S, Verri T, Rimoldi S, Bernardini G, Saroglia M (2009) Impact of feed availability on PepT1 mRNA expression levels in sea bass (Dicentrarchus labrax). Aquaculture 294:288–299
97. Tian J, Wen H, Zeng L-B, Jiang M, Wu F, Liu W, Yang C-G (2013) Changes in the activities and mRNA expression levels of lipoprotein lipase (LPL), hormone-sensitive lipase (HSL) and fatty acid synthetase (FAS) of Nile tilapia (Oreochromis niloticus) during fasting and re-feeding. Aquaculture 400–401:29–35
98. Trombley S, Schmitz M (2013) Leptin in fish: possible role in sexual maturation in male Atlantic salmon. Fish Physiol Biochem 39:103–106
99. Ulloa P, Iturra P, Neira R, Araneda C (2011) Zebrafish as a model organism for nutrition and growth: towards comparative studies of nutritional genomics applied to aquacultured fishes. Rev Fish Biol Fish 21:649–666
100. Unniappan S, Canosa LF, Peter RE (2004) Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responses to central and peripheral injections. Neuroendocrinology 79:100–108
101. Volkoff H, Peter RE (2006) Feeding behavior of fish and its control. Zebrafish 3:131–140
102. Volkoff H, Canosa L, Unniappan S, Cerda-Reverter J, Bernier N, Kelly S, Peter R (2005) Neuropeptides and the control of food intake in fish. Gen Comp Endocrinol 142:3–19
103. Wade N, Skiba-Cassy S, Dias K, Glencross B (2014) Postprandial molecular responses in the liver of the barramundi, Lates calcarifer. Fish Physiol Biochem 40:427–443
104. Wakil SJ (1989) Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry 28:4523–4530
105. Wall A, Volkoff H (2013) Effects of fasting and feeding on the brain mRNA expressions of orexin, tyrosine hydroxylase (TH), PYY and CCK in the Mexican blind cavefish (Astyanax fasciatus mexicanus). Gen Comp Endocrinol 183:44–52
106. Watts SA, Powell M, D’Abramo LR (2012) Fundamental approaches to the study of zebrafish nutrition. ILAR J 53:144–160
107. Weil C, Lefèvre F, Bugeon J (2013) Characteristics and metabolism of different adipose tissues in fish. Rev Fish Biol Fish 23:157–173
108. White JD (1993) Neuropeptide Y: a central regulator of energy homeostasis. Regul Pept 49:93–107
109. Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S (2013) Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish. PLoS Genet 9:e1003852
110. Xu M, Volkoff H (2009) Molecular characterization of ghrelin and gastrin-releasing peptide in Atlantic cod (Gadus morhua): cloning, localization, developmental profile and role in food intake regulation. Gen Comp Endocrinol 160:250–258
111. Yokobori E, Azuma M, Nishiguchi R, Kang KS, Kamijo M, Uchiyama M, Matsuda K (2012) Neuropeptide Y stimulates food intake in the zebrafish, Danio rerio. J Neuroendocrinol 24:766–773
112. Zhou Y, Liang X-F, Yuan X, Li J, He Y, Fang L, Guo X, Liu L, Li B, Shen D (2013) Neuropeptide Y stimulates food intake and regulates metabolism in grass carp, Ctenopharyngodon idellus. Aquaculture 380–383:52–61