Regional differences in the expression of genes involved in lipid metabolism in adipose tissue in response to short- and medium-term fasting and refeeding

Journal of Nutritional Biochemistry

Volumn 21, Issue 1, 2010, Pages 23-33

  Palou, Mariona ^a,b   Sánchez, Juana ^a,b   Priego, Teresa ^a,b   Rodríguez, Ana M ^a,b   Picó, Catalina ^a,b   Palou, Andreu ^a,b  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Food deprivation; Gene expression; Lipogenesis; Lipolysis; White adipose tissue depots

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE ALPHA; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A; FATTY ACID SYNTHASE; GLUCOSE TRANSPORTER 4; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HORMONE SENSITIVE LIPASE; LIPOPROTEIN LIPASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FATTY ACID OXIDATION; GENE EXPRESSION REGULATION; GENE LOCATION; INGUINAL REGION; LIPID METABOLISM; LIPOGENESIS; LIPOLYSIS; MALE; MESENTERY; NONHUMAN; PROTEIN EXPRESSION; RAT; REFEEDING; RETROPERITONEAL FAT; SUBCUTANEOUS FAT;

ABDOMINAL FAT; ADIPOSE TISSUE, WHITE; ANIMALS; FASTING; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; FOOD; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORTER TYPE 4; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; INTRA-ABDOMINAL FAT; LIPID METABOLISM; MALE; MESENTERY; PPAR GAMMA; RATS; RATS, WISTAR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

RATTUS;

EID: 71749084311     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.10.001     Document Type: Article

References (49)

1. Giorgino F., Laviola L., and Eriksson J.W. Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies. Acta Physiol Scand. 183 (2005) 13-30
2. Palou A., Remesar X., Arola L., Herrera E., and Alemany M. Metabolic effects of short term food deprivation in the rat. Horm Metab Res. 13 (1981) 326-330
3. Goodman M.N., Larsen P.R., Kaplan M.M., Aoki T.T., Young V.R., and Ruderman N.B. Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism. Am J Physiol. 239 (1980) E277-E286
4. Finn P.F., and Dice J.F. Proteolytic and lipolytic responses to starvation. Nutrition. 22 (2006) 830-844
5. Zimmermann R., Strauss J.G., Haemmerle G., Schoiswohl G., Birner-Gruenberger R., Riederer M., et al. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science. 306 (2004) 1383-1386
6. Villena J.A., Roy S., Sarkadi-Nagy E., Kim K.H., and Sul H.S. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J Biol Chem. 279 (2004) 47066-47075
7. Hashimoto T. Peroxisomal beta-oxidation enzymes. Neurochem Res. 24 (1999) 551-563
8. Rosen E.D., and Spiegelman B.M. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem. 276 (2001) 37731-37734
9. Gosmain Y., Dif N., Berbe V., Loizon E., Rieusset J., Vidal H., et al. Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues. J Lipid Res. 46 (2005) 697-705
10. Feige J.N., Gelman L., Michalik L., Desvergne B., and Wahli W. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res. 45 (2006) 120-159
11. Wu Z., Xie Y., Morrison R.F., Bucher N.L., and Farmer S.R. PPARgamma induces the insulin-dependent glucose transporter GLUT4 in the absence of C/EBPalpha during the conversion of 3T3 fibroblasts into adipocytes. J Clin Invest. 101 (1998) 22-32
12. Foufelle F., and Ferre P. New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c. Biochem J. 366 (2002) 377-391
13. Osborne T.F. Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem. 275 (2000) 32379-32382
14. Fajas L., Schoonjans K., Gelman L., Kim J.B., Najib J., Martin G., et al. Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Cell Biol. 19 (1999) 5495-5503
15. Kim J.B., Wright H.M., Wright M., and Spiegelman B.M. ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci U S A. 95 (1998) 4333-4337
16. Cagen L.M., Deng X., Wilcox H.G., Park E.A., Raghow R., and Elam M.B. Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements. Biochem J. 385 (2005) 207-216
17. Despres J.P., Nadeau A., Tremblay A., Ferland M., Moorjani S., Lupien P.J., et al. Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes. 38 (1989) 304-309
18. Ross R., Fortier L., and Hudson R. Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care. 19 (1996) 1404-1411
19. Kelley D.E., Thaete F.L., Troost F., Huwe T., and Goodpaster B.H. Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol Endocrinol Metab. 278 (2000) E941-E948
20. Ronnemaa T., Koskenvuo M., Marniemi J., Koivunen T., Sajantila A., Rissanen A., et al. Glucose metabolism in identical twins discordant for obesity. The critical role of visceral fat. J Clin Endocrinol Metab. 82 (1997) 383-387
21. Despres J.P. Health consequences of visceral obesity. Ann Med. 33 (2001) 534-541
22. Weiss R. Fat distribution and storage: how much, where, and how?. Eur J Endocrinol. 157 Suppl 1 (2007) S39-S45
23. Arner P., Hellstrom L., Wahrenberg H., and Bronnegard M. Beta-adrenoceptor expression in human fat cells from different regions. J Clin Invest. 86 (1990) 1595-1600
24. Chaston T.B., and Dixon J.B. Factors associated with percent change in visceral versus subcutaneous abdominal fat during weight loss: findings from a systematic review. Int J Obes (Lond). 32 (2008) 619-628
25. Sugden M.C., Grimshaw R.M., Lall H., and Holness M.J. Regional variations in metabolic responses of white adipose tissue to food restriction. Am J Physiol. 267 (1994) E892-E899
26. Virtanen K.A., Lonnroth P., Parkkola R., Peltoniemi P., Asola M., Viljanen T., et al. Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans. J Clin Endocrinol Metab. 87 (2002) 3902-3910
27. Svedberg J., Bjorntorp P., Smith U., and Lonnroth P. Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes. 39 (1990) 570-574
28. Boden G. Free fatty acids (FFA), a link between obesity and insulin resistance. Front Biosci. 3 (1998) d169-d175
29. Boden G., and Chen X. Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes. J Clin Invest. 96 (1995) 1261-1268
30. Roden M., Price T.B., Perseghin G., Petersen K.F., Rothman D.L., Cline G.W., et al. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. 97 (1996) 2859-2865
31. Palou M., Priego T., Sanchez J., Villegas E., Rodriguez A.M., Palou A., et al. Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting. Pflugers Arch. 456 (2008) 825-836
32. Sanchez J., Oliver P., Pico C., and Palou A. Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats. Pflugers Arch. 448 (2004) 500-506
33. Priego T., Sanchez J., Pico C., and Palou A. Sex-differential expression of metabolism-related genes in response to a high-fat diet. Obesity (Silver Spring). 16 (2008) 819-826
34. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
35. Frayn K.N., Coppack S.W., Fielding B.A., and Humphreys S.M. Coordinated regulation of hormone-sensitive lipase and lipoprotein lipase in human adipose tissue in vivo: implications for the control of fat storage and fat mobilization. Adv Enzyme Regul. 35 (1995) 163-178
36. Vidal-Puig A.J., Considine R.V., Jimenez-Linan M., Werman A., Pories W.J., Caro J.F., et al. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest. 99 (1997) 2416-2422
37. Mauriege P., Galitzky J., Berlan M., and Lafontan M. Heterogeneous distribution of beta and alpha-2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences. Eur J Clin Invest. 17 (1987) 156-165
38. Lonnqvist F., Krief S., Strosberg A.D., Nyberg S., Emorine L.J., and Arner P. Evidence for a functional beta 3-adrenoceptor in man. Br J Pharmacol. 110 (1993) 929-936
39. Bertile F., Criscuolo F., Oudart H., Le Maho Y., and Raclot T. Differences in the expression of lipolytic-related genes in rat white adipose tissues. Biochem Biophys Res Commun. 307 (2003) 540-546
40. Sivitz W.I., DeSautel S.L., Kayano T., Bell G.I., and Pessin J.E. Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin. Mol Endocrinol. 4 (1990) 583-588
41. Eckel R.H. Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N Engl J Med. 320 (1989) 1060-1068
42. Fried S.K., and Kral J.G. Sex differences in regional distribution of fat cell size and lipoprotein lipase activity in morbidly obese patients. Int J Obes. 11 (1987) 129-140
43. Pedersen S.B., Jonler M., and Richelsen B. Characterization of regional and gender differences in glucocorticoid receptors and lipoprotein lipase activity in human adipose tissue. J Clin Endocrinol Metab. 78 (1994) 1354-1359
44. Wu G., Olivecrona G., and Olivecrona T. The distribution of lipoprotein lipase in rat adipose tissue. Changes with nutritional state engage the extracellular enzyme. J Biol Chem. 278 (2003) 11925-11930
45. Doolittle M.H., Ben-Zeev O., Elovson J., Martin D., and Kirchgessner T.G. The response of lipoprotein lipase to feeding and fasting. Evidence for posttranslational regulation. J Biol Chem. 265 (1990) 4570-4577
46. Bergo M., Wu G., Ruge T., and Olivecrona T. Down-regulation of adipose tissue lipoprotein lipase during fasting requires that a gene, separate from the lipase gene, is switched on. J Biol Chem. 277 (2002) 11927-11932
47. Le Lay S., Lefrere I., Trautwein C., Dugail I., and Krief S. Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes. Identification of CCAAT/enhancer-binding protein beta as an SREBP-1C target. J Biol Chem. 277 (2002) 35625-35634
48. Wolf G. The mechanism and regulation of fat mobilization from adipose tissue: desnutrin, a newly discovered lipolytic enzyme. Nutr Rev. 63 (2005) 166-170
49. Sztalryd C., and Kraemer F.B. Regulation of hormone-sensitive lipase during fasting. Am J Physiol. 266 (1994) E179-E185