CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism

Cellular Signalling

Volumn 27, Issue 6, 2015, Pages 1253-1263

  Vlahava, Virginia Maria ^a   Eliopoulos, Aristides G ^a,b   Sourvinos, George ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

Author keywords

Atg5; Autophagy; CD40 ligand; HSV 1; PIK3K; VP16

Indexed keywords

2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; ANTIVIRUS AGENT; ATG5 PROTEIN, HUMAN; BAFILOMYCIN A1; BENZYLAMINE DERIVATIVE; CD40 LIGAND; CHROMONE DERIVATIVE; LIGHT CHAIN 3, HUMAN; MACROLIDE; MICROTUBULE ASSOCIATED PROTEIN; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; QUINAZOLINE DERIVATIVE; SMALL INTERFERING RNA; SPAUTIN-1; STRESS ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN;

ANTAGONISTS AND INHIBITORS; AUTOPHAGY; CELL NUCLEUS; DRUG EFFECTS; GENETICS; HERPES SIMPLEX VIRUS 1; HUMAN; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VIRUS REPLICATION;

ANTHRACENES; ANTIVIRAL AGENTS; AUTOPHAGY; BENZYLAMINES; CD40 LIGAND; CELL LINE, TUMOR; CELL NUCLEUS; CHROMONES; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 1, HUMAN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROLIDES; MICROTUBULE-ASSOCIATED PROTEINS; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; QUINAZOLINES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84939956091     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.03.002     Document Type: Article

References (58)

1. Steiner I., Benninger F. Curr. Neurol. Neurosci. Rep. 2013, 13:414.
2. Smith C., Khanna R. Am. J. Transplant. 2013, 13(Suppl. 3):9-23. (quiz 23).
3. Wertheim J.O., Smith M.D., Smith D.M., Scheffler K., Kosakovsky Pond S.L. Mol. Biol. Evol. 2014, 31:2356-2364.
4. Connolly S.A., Jackson J.O., Jardetzky T.S., Longnecker R. Nat. Rev. Microbiol. 2011, 9:369-381.
5. Wysocka J., Herr W. Trends Biochem. Sci. 2003, 28:294-304.
6. Arvin A., Campadelli-Fiume G., Mocarski E., Moore P.S., Roizman B., Whitley R., Yamanishi K. Human Herpesviruses Biology, Therapy, and Immunoprophylaxis 2007, Cambridge University Press.
7. Chew T., Taylor K.E., Mossman K.L. Viruses 2009, 1:979-1002.
8. Ruby J., Bluethmann H., Aguet M., Ramshaw I.A. Nat. Med. 1995, 1:437-441.
9. Beland J.L., Adler H., Del-Pan N.C., Kozlow W., Sung J., Fanslow W., Rimm I.J. Blood 1998, 92:4472-4478.
10. Inagaki-Ohara K., Kawabe T., Hasegawa Y., Hashimoto N., Nishiyama Y. Arch. Virol. 2002, 147:187-194.
11. Edelmann K.H., Wilson C.B. J. Virol. 2001, 75:612-621.
12. Winkelstein J.A., Marino M.C., Ochs H., Fuleihan R., Scholl P.R., Geha R., Stiehm E.R., Conley M.E. Medicine (Baltimore) 2003, 82:373-384.
13. García-Pérez M.A., Paz-Artal E., Corell A., Moreno A., López-Goyanes A., García-Martín F., Vázquez R., Pacho A., Romo E., Allende L.M. Immunobiology 2003, 207:285-294.
14. Tan J., Town T., Mori T., Obregon D., Wu Y., DelleDonne A., Rojiani A., Crawford F., Flavell R.A., Mullan M. EMBO J. 2002, 21:643-652.
15. Schönbeck U., Libby P. Cell. Mol. Life Sci. 2001, 58:4-43.
16. Elgueta R., Benson M.J., de Vries V.C., Wasiuk A., Guo Y., Noelle R.J. Immunol. Rev. 2009, 229:152-172.
17. Andrade R.M., Wessendarp M., Gubbels M.J., Striepen B., Subauste C.S. J. Clin. Invest. 2006, 116:2366-2377.
18. Subauste C.S., Andrade R.M., Wessendarp M. Autophagy 2007, 3:245-248.
19. Portillo J.A., Okenka G., Reed E., Subauste A., Van Grol J., Gentil K., Komatsu M., Tanaka K., Landreth G., Levine B., Subauste C.S. PLoS One 2010, 5:e14472.
20. Van Grol J., Muniz-Feliciano L., Portillo J.A., Bonilha V.L., Subauste C.S. Infect. Immun. 2013, 81:2002-2011.
21. Leiva L.E., Junprasert J., Hollenbaugh D., Sorensen R.U. J. Clin. Immunol. 1998, 18:283-290.
22. Orvedahl A., Levine B. Cell. Microbiol. 2008, 10:1747-1756.
23. Schmid D., Münz C. Immunity 2007, 27:11-21.
24. Levine B., Deretic V. Nat. Rev. Immunol. 2007, 7:767-777.
25. McKnight N.C., Zhong Y., Wold M.S., Gong S., Phillips G.R., Dou Z., Zhao Y., Heintz N., Zong W.X., Yue Z. PLoS Genet. 2014, 10:e1004626.
26. Orvedahl A., Alexander D., Tallóczy Z., Sun Q., Wei Y., Zhang W., Burns D., Leib D.A., Levine B. Cell Host Microbe 2007, 1:23-35.
27. Tang S., Bertke A.S., Patel A., Wang K., Cohen J.I., Krause P.R. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:10931-10936.
28. Tang S., Patel A., Krause P.R. J. Virol. 2009, 83:1433-1442.
29. Lussignol M., Queval C., Bernet-Camard M.F., Cotte-Laffitte J., Beau I., Codogno P., Esclatine A. J. Virol. 2013, 87:859-871.
30. Parkhitko A.A., Favorova O.O., Henske E.P. Biochemistry (Mosc) 2013, 78:355-367.
31. Lamb C.A., Yoshimori T., Tooze S.A. Nat. Rev. Mol. Cell Biol. 2013, 14:759-774.
32. Carpentier S., N'Kuli F., Grieco G., Van Der Smissen P., Janssens V., Emonard H., Bilanges B., Vanhaesebroeck B., Gaide Chevronnay H.P., Pierreux C.E., Tyteca D., Courtoy P.J. Traffic 2013, 14:933-948.
33. Vanhaesebroeck B., Guillermet-Guibert J., Graupera M., Bilanges B. Nat. Rev. Mol. Cell Biol. 2010, 11:329-341.
34. Kim Y.M., Jung C.H., Seo M., Kim E.K., Park J.M., Bae S.S., Kim D.H. Mol. Cell 2015, 57:207-218.
35. Korolchuk V.I., Saiki S., Lichtenberg M., Siddiqi F.H., Roberts E.A., Imarisio S., Jahreiss L., Sarkar S., Futter M., Menzies F.M., O'Kane C.J., Deretic V., Rubinsztein D.C. Nat. Cell Biol. 2011, 13:453-460.
36. Kondratskyi A., Yassine M., Kondratska K., Skryma R., Slomianny C., Prevarskaya N. Front. Physiol. 2013, 4:272.
37. Pullen S.S., Dang T.T., Crute J.J., Kehry M.R. J. Biol. Chem. 1999, 274:14246-14254.
38. de Oliveira A.P., Glauser D.L., Laimbacher A.S., Strasser R., Schraner E.M., Wild P., Ziegler U., Breakefield X.O., Ackermann M., Fraefel C. J. Virol. 2008, 82:4974-4990.
39. Everett R.D., Sourvinos G., Leiper C., Clements J.B., Orr A. J. Virol. 2004, 78:1903-1917.
40. Polioudaki H., Kastrinaki M.C., Papadaki H.A., Theodoropoulos P.A. Cell Prolif. 2009, 42:434-447.
41. Dalrymple M.A., McGeoch D.J., Davison A.J., Preston C.M. Nucleic Acids Res. 1985, 13:7865-7879.
42. Davies C.C., Mason J., Wakelam M.J., Young L.S., Eliopoulos A.G. J. Biol. Chem. 2004, 279:1010-1019.
43. Blommaart E.F., Krause U., Schellens J.P., Vreeling-Sindelárová H., Meijer A.J. Eur. J. Biochem. 1997, 243:240-246.
44. Liu J., Xia H., Kim M., Xu L., Li Y., Zhang L., Cai Y., Norberg H.V., Zhang T., Furuya T., Jin M., Zhu Z., Wang H., Yu J., Hao Y., Choi A., Ke H., Ma D., Yuan J. Cell 2011, 147:223-234.
45. Davies C.C., Mak T.W., Young L.S., Eliopoulos A.G. Mol. Cell. Biol. 2005, 25:9806-9819.
46. Li D.D., Wang L.L., Deng R., Tang J., Shen Y., Guo J.F., Wang Y., Xia L.P., Feng G.K., Liu Q.Q., Huang W.L., Zeng Y.X., Zhu X.F. Oncogene 2009, 28:886-898.
47. Yoshimori T., Yamamoto A., Moriyama Y., Futai M., Tashiro Y. J. Biol. Chem. 1991, 266:17707-17712.
48. Yamamoto A., Tagawa Y., Yoshimori T., Moriyama Y., Masaki R., Tashiro Y. Cell Struct. Funct. 1998, 23:33-42.
49. Hanada T., Noda N.N., Satomi Y., Ichimura Y., Fujioka Y., Takao T., Inagaki F., Ohsumi Y. J. Biol. Chem. 2007, 282:37298-37302.
50. Romanov J., Walczak M., Ibiricu I., Schüchner S., Ogris E., Kraft C., Martens S. EMBO J. 2012, 31:4304-4317.
51. Yao F., Schaffer P.A. J. Virol. 1995, 69:6249-6258.
52. Sodeik B., Ebersold M.W., Helenius A. J. Cell Biol. 1997, 136:1007-1021.
53. Nicola A.V., Hou J., Major E.O., Straus S.E. J. Virol. 2005, 79:7609-7616.
54. Nicola A.V., McEvoy A.M., Straus S.E. J. Virol. 2003, 77:5324-5332.
55. Futter C.E., Collinson L.M., Backer J.M., Hopkins C.R. J. Cell Biol. 2001, 155:1251-1264.
56. Kim J.Y., Mandarino A., Chao M.V., Mohr I., Wilson A.C. PLoS Pathog. 2012, 8:e1002540.
57. Camarena V., Kobayashi M., Kim J.Y., Roehm P., Perez R., Gardner J., Wilson A.C., Mohr I., Chao M.V. Cell Host Microbe 2010, 8:320-330.
58. Wilcox D.R., Wadhwani N.R., Longnecker R., Muller W.J. PLoS Pathog. 2015, 11:e1004580.