An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 31, 2008, Pages 10931-10936

  Tang, Shuang ^a   Bertke, Andrea S ^a   Patel, Amita ^a   Wang, Kening ^b   Cohen, Jeffrey I ^b   Krause, Philip R ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

HSV; Human; Latency; Latency associated transcript; Reactivation

Indexed keywords

MICRORNA; PROTEIN ICP34.5; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL CULTURE; CELL MATURATION; CONTROLLED STUDY; EXON; FEMALE; GENETIC TRANSFECTION; GUINEA PIG; HERPES SIMPLEX VIRUS 2; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; SENSORY GANGLION; SPINAL GANGLION; VIRUS INFECTION; VIRUS LATENCY; VIRUS VIRULENCE;

ADULT; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CELL LINE; DNA PRIMERS; GANGLIA, SPINAL; GENE COMPONENTS; GENE EXPRESSION REGULATION, VIRAL; GUINEA PIGS; HERPESVIRUS 2, HUMAN; HUMANS; LUCIFERASES; MALE; MICRORNAS; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEURONS, AFFERENT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRAL PROTEINS; VIRUS LATENCY;

CAVIA; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; SIMPLEXVIRUS;

EID: 49449099065     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801845105     Document Type: Article

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