Fibroblast growth factor (FGF21) protects mouse liver against d-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways

Molecular and Cellular Biochemistry

Volumn 403, Issue 1-2, 2015, Pages 287-299

  Yu, Yinhang ^a   Bai, Fuliang ^a   Liu, Yaonan ^a   Yang, Yongbi ^a   Yuan, Qingyan ^a   Zou, Dehua ^d   Qu, Susu ^c   Tian, Guiyou ^a   Song, Liying ^a   Zhang, Tong ^a   Li, Siming ^b   Liu, YunYe ^a   Wang, Wenfei ^a   Ren, Guiping ^a   Li, Deshan ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b HARBIN UNIVERSITY OF COMMERCE   (China)

^c INSTITUTE OF PSYCHOLOGY   (China)

^d HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

Author keywords

Apoptosis; d Gal; FGF21; Nrf2 mediated antioxidant capacity; PI3K AKT

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; CASPASE 3; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 21; NFE2L2 PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTECTIVE AGENT; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; APOPTOSIS; CELL NUCLEUS; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; LIVER; LIVER CELL; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BIOMARKERS; CASPASE 3; CELL NUCLEUS; ENZYME ACTIVATION; FIBROBLAST GROWTH FACTORS; HEPATOCYTES; LIVER; MALE; MICE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTECTIVE AGENTS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84939932976     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2358-6     Document Type: Article

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