IGF-1R reduction triggers neuroprotective signaling pathways in spinal muscular atrophy mice

Journal of Neuroscience

Volumn 35, Issue 34, 2015, Pages 12063-12079

  Biondi, Olivier ^a   Branchu, Julien ^a   Salah, Amina Ben ^a   Houdebine, Léo ^a   Bertin, Lise ^a   Chali, Farah ^a   Desseille, Céline ^a   Weill, Laure ^a   Sanchez, Gabriel ^b   Lancelin, Camille ^a   Aïd, Saba ^c   Lopes, Philippe ^a,d   Pariset, Claude ^a   Lécolle, Sylvie ^a   Côté, Jocelyn ^b   Holzenberger, Martin ^c   Chanoine, Christophe ^a   Massaad, Charbel ^a   Charbonnier, Frédéric ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITY OF OTTAWA   (Canada)

^c SORBONNE UNIVERSITÉ   (France)

^d UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

Gene expression; IGF 1R; Model mice; Signaling pathways; SMN; Spinal muscular atrophy

Indexed keywords

ALPHA BUNGAROTOXIN; CHOLINERGIC RECEPTOR; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; SOMATOMEDIN C RECEPTOR; SURVIVAL MOTOR NEURON PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR ASSESSMENT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXERCISE; FEMALE; GENE EXPRESSION; GENOTYPE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; LOCOMOTION; MALE; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL MUSCULAR ATROPHY; SURVIVAL; WESTERN BLOTTING; ANIMAL; CELL CULTURE; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MUSCULAR ATROPHY, SPINAL; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CELLS, CULTURED; FEMALE; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCULAR ATROPHY, SPINAL; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION;

EID: 84939866192     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0608-15.2015     Document Type: Article

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