Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis

Lancet

Volumn 361, Issue 9362, 2003, Pages 1007-1011

  Wilczak, Nadine ^a   De Vos, Rob A I ^b   De Keyser, Jacques ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Oost Nederland ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN BINDING PROTEIN 6; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; SPINAL CORD VENTRAL HORN; UPREGULATION; WESTERN BLOTTING;

EID: 0037460835     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12828-0     Document Type: Article

References (27)

1. Rowland L.P., Shneider N.A. Amyotrophic lateral sclerosis. N Engl J Med. 344:2001;1688-1700.
2. Brooke M.H., Strong M.J. Advances in ALS workshop summary: research and future goals. Neurology. 47:(suppl):1996;S108-S112.
3. Lewis M.E., Neff N.T., Contreras P.C., et al. Insulin-like growth factor-I: potential for treatment of motor neuronal disorders. Exp Neurol. 124:1993;73-88.
4. Festoff B.W., Yang S.X., Vaught J., Bryan C., Ma J.Y. The insulin-like growth factor signaling system and ALS neurotrophic factor treatment strategies. J Neurol Sci. 129:(suppl):1995;114-121.
5. Lai E.C., Felice K.J., Festoff B.W., et al. Effect of recombinant human insulin-like growth factor-I on progression of ALS: a placebo-controlled study. Neurology. 49:1997;1621-1630.
6. Borasio G.D., Robberecht W., Leigh P.N., et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. Neurology. 51:1998;583-586.
7. Clemmons D.R. Insulin-like growth factor binding proteins and their role in controlling IGF actions. Cytokine Growth Factor Rev. 8:1997;45-62.
8. Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev. 16:1995;3-34.
9. Braunstein G.D., Reviczky A.L. Serum insulin-like growth factor-I levels in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 50:1987;792-794.
10. Denys E.H., Pelle-Day G., Spencer E.M. Somatomedin-C is not increased in the serum of patients with amyotrophic lateral sclerosis. Muscle Nerve. 11:1988;1000-1001.
11. Torres-Aleman I., Barrios V., Berciano J. The peripheral insulin-like growth factor system in amyotrophic lateral sclerosis and in multiple sclerosis. Neurology. 50:1998;772-776.
12. Kerkhoff H., Hassan S.M., Troost D., Van Etten R.W., Veldman H., Jennekens F.G. Insulin-like and fibroblast growth factors in spinal cords, nerve roots and skeletal muscle of human controls and patients with amyotrophic lateral sclerosis. Acta Neuropathol (Berl). 87:1994;411-421.
13. Adem A., Ekblom J., Gillberg P.G. Growth factor receptors in amyotrophic lateral sclerosis. Mol Neurobiol. 9:1994;225-231.
14. Dore S., Krieger C., Kar S., Quirion R. Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients. Brain Res Mol Brain Res. 41:1996;128-133.
15. Brooks B.R. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci. 124:(suppl):1994;96-107.
16. Neuhoff V., Philipp K., Zimmer H.G., Mesecke S. A simple, versatile, sensitive and volume-independent method for quantitative protein determination which is independent of other external influences. Hoppe Seylers Z Physiol Chem. 360:1979;1657-1670.
17. Gustafsson T., Andersson P., Arnqvist H.J. Different inhibitory actions of IGFBP-1, -2 and -4 on IGF-I effects in vascular smooth muscle cells. J Endocrinol. 161:1999;245-253.
18. Hoeflich A., Wu M., Mohan S., et al. Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain. Endocrinology. 140:1999;5488-5496.
19. D'Costa A.P., Prevette D.M., Houenou L.J., et al. Mechanisms of insulin-like growth factor regulation of programmed cell death of developing avian motoneurons. J Neurobiol. 36:1998;379-394.
20. Babajko S., Leneuve P., Loret C., Binoux M. IGF-binding protein-6 is involved in growth inhibition in SH-SY5Y human neuroblastoma cells: its production is both IGF- and cell density-dependent. J Endocrinol. 152:1997;221-227.
21. Sueoka N., Lee H.Y., Walsh G.L., et al. Insulin-like growth factor binding protein-6 inhibits the growth of human bronchial epithelial cells and increases in abundance with all-trans- retinoic acid treatment. Am J Respir Cell Mol Biol. 23:2000;297-303.
22. Sueoka N., Lee H.Y., Wiehle S., et al. Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells. Oncogene. 19:2000;4432-4436.
23. Hammarberg H., Risling M., Hokfelt T., Cullheim S., Piehl F. Expression of insulin-like growth factors and corresponding binding proteins (IGFBP 1-6) in rat spinal cord and peripheral nerve after axonal injuries. J Comp Neurol. 400:1998;57-72.
24. Yuan Q., Wu W., So K.F., Cheung A.L., Prevette D.M., Oppenheim R.W. Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats. Neuroreport. 11:2000;2237-2241.
25. Chou S.M., Taniguchi A., Wang H.S., Festoff B.W. Serpin=serine protease-like complexes within neurofilament conglomerates of motoneurons in amyotrophic lateral sclerosis. J Neurol Sci. 160:(suppl):1998;S73-S79.
26. Meins M., Piosik P., Schaeren-Wiemers N., et al. Progressive neuronal and motor dysfunction in mice overexpressing the serine protease inhibitor protease nexin-1 in postmitotic neurons. J Neurosci. 21:2001;8830-8841.
27. Loddick S.A., Liu X.J., Lu Z.X., et al. Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke. Proc Natl Acad Sci USA. 95:1998;1894-1898.