Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 33, 2015, Pages E4565-E4570

  Schalbetter, Stephanie A ^a   Mansoubi, Sahar ^a   Chambers, Anna L ^a,b   Downs, Jessica A ^a   Baxter, Jonathan ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

DNA catenation; DNA replication; DNA topology; Fork rotation; Topoisomerases

Indexed keywords

DNA; DNA TOPOISOMERASE; PROTEIN TIMELESS; CELL CYCLE PROTEIN; CSM3P PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); FUNGAL DNA; SACCHAROMYCES CEREVISIAE PROTEIN; TOF1 PROTEIN, S CEREVISIAE;

ANEUPLOIDY; ARTICLE; BUDDING; CHROMOSOMAL INSTABILITY; CHROMOSOME DUPLICATION; DNA CATENATION; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; GENOMIC INSTABILITY; NONHUMAN; PRIORITY JOURNAL; REPLICON; REPLISOME; YEAST; BUDDING YEAST; CELL CYCLE; CHEMISTRY; GENE DELETION; GENETICS; GENOTYPE; MARKOV CHAIN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PLASMID;

SACCHAROMYCETALES;

CELL CYCLE; CELL CYCLE PROTEINS; CHROMOSOMAL INSTABILITY; DNA; DNA REPLICATION; DNA TOPOISOMERASES, TYPE II; DNA, FUNGAL; DNA-BINDING PROTEINS; GENE DELETION; GENOTYPE; PHOSPHORYLATION; PLASMIDS; SACCHAROMYCES CEREVISIAE PROTEINS; SACCHAROMYCETALES; STOCHASTIC PROCESSES;

EID: 84939863151     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1505356112     Document Type: Article

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