Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 7, 2013, Pages 2523-2527

  Cho, Won Ho ^a   Kang, Young Hoon ^b   An, Yun Young ^a   Tappin, Inger ^b   Hurwitz, Jerard ^b   Lee, Joon Kyu ^a  

^a Seoul National University   (South Korea)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Fork movement; Genome integrity; Replication checkpoint

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BINDING PROTEIN; DNA POLYMERASE; HELICASE; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7; PROTEIN TIMELESS; SINGLE STRANDED DNA; TIPIN PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BIOCHEMICAL COMPOSITION; CATALYSIS; DNA DENATURATION; DNA PROTEIN COMPLEX; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; EUKARYOTE; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN NUCLEIC ACID INTERACTION; PROTEIN PURIFICATION;

CARRIER PROTEINS; CELL CYCLE PROTEINS; DNA HELICASES; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; OLIGONUCLEOTIDES;

EID: 84873732346     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222494110     Document Type: Article

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