Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies

European Journal of Medicinal Chemistry

Volumn 102, Issue , 2015, Pages 413-424

  Senwar, Kishna Ram ^a   Sharma, Pankaj ^a   Reddy, T Srinivasa ^b   Jeengar, Manish Kumar ^a   Nayak, V Lakshma ^b   Naidu, V G M ^a   Kamal, Ahmed ^b   Shankaraiah, Nagula ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1,3 Dipolar cycloaddition; Anticancer; Apoptosis; Epoxide; Morpholine fused 1,2,3 triazole; Spirooxindole

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOTOXIN; INDOLE DERIVATIVE; MORPHOLINE; MORPHOLINE DERIVATIVE; SPIRO COMPOUND; TRIAZOLE DERIVATIVE;

APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECTS; DRUG SCREENING; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; MOLECULAR STRUCTURE; MORPHOLINES; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84939785456     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.08.017     Document Type: Article

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