Docosahexaenoic acid induces cell death in human non-small cell lung cancer cells by repressing mTOR via AMPK activation and PI3K/Akt inhibition

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Kim, Nayeong ^a   Jeong, Soyeon ^a   Jing, Kaipeng ^b   Shin, Soyeon ^a   Kim, Soyeon ^a   Heo, Jun Young ^a   Kweon, Gi Ryang ^a   Park, Seung Kiel ^a   Wu, Tong ^c   Park, Jong Il ^a   Lim, Kyu ^a  

^a Chungnam National University   (South Korea)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCOSAHEXAENOIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL CULTURE; CANCER GROWTH; CANCER SIZE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARCINOMA, NON-SMALL-CELL LUNG; DRUG EFFECTS; GENETICS; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

MUS; MUS MUSCULUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DOCOSAHEXAENOIC ACIDS; HUMANS; MICE; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84939627589     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/239764     Document Type: Article

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