Parenteral Lipid Tolerance and Adverse Effects

Journal of Parenteral and Enteral Nutrition

Volumn 39, Issue , 2015, Pages 33S-38S

  Wanten, Geert J A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

adult; fatty acids; home nutrition support; life cycle; lipids; nutrition; parenteral formulas compounding; parenteral nutrition; research and diseases

Indexed keywords

LIPID; LIPID EMULSION; FAT INTAKE; FISH OIL; UNSATURATED FATTY ACID; VEGETABLE OIL;

BLOOD CLOTTING DISORDER; CHEMICAL COMPOSITION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERSENSITIVITY; HYPERTRIGLYCERIDEMIA; INFECTION; INTESTINAL FAILURE; LIPID METABOLISM; LUNG DISEASE; OBESITY; OXIDATIVE STRESS; PARENTERAL NUTRITION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; ADVERSE EFFECTS; ANIMAL; CHEMISTRY; FAT INTAKE; INFLAMMATION; PHARMACOLOGY; PROCEDURES; THERAPEUTIC USE;

GLYCINE MAX;

ANIMALS; DIETARY FATS; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, UNSATURATED; FISH OILS; HUMANS; INFLAMMATION; PARENTERAL NUTRITION; PLANT OILS;

EID: 84939620467     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1177/0148607115595973     Document Type: Review

References (48)

1. Vinnars E, Hammarqvist F., 25th Arvid Wretlinds Lecture-Silver anniversary, 25 years with ESPEN, the history of nutrition. Clin Nutr. 2004; 23: 955-962.
2. Calder PC, Koletzko B, Singer P, Jensen G, Wanten G., Lipid emulsions in parenteral nutrition: current thinking and future directions. Intensive Care Med. 2010; 36: 735-49.
3. Driscoll DF., Commercial lipid emulsions and all-in-one mixtures for intravenous infusion-composition and physicochemical properties. World Rev Nutr Diet. 2015; 112: 48-56.
4. Food and Drug Administration. Intralipid 20%. http://www.accessdata.fda.gov/drugsatfda-docs/label/2007/017643s072,018449s039lbl.pdf. Accessed March 25, 2015.
5. Mirtallo JM, Dasta JF, Kleinschmidt KC, Caron J., State of the art review: intravenous fat emulsions: current applications, safety profile, and clinical implications. Ann Pharmacother. 2010; 44: 688-700.
6. Wanten G, Naber A., Cellular and physiologic effects of medium chain triglycerides. Mini Rev Med Chem. 2004; 4: 847-857.
7. Wanten G, Calder PC, Forbes A., Managing adult patients who need home parenteral nutrition. BMJ. 2011; 342: d1447.
8. Tillman EM., Review and clinical update on parenteral nutrition-associated liver disease. Nutr Clin Pract. 2013; 28: 30-39.
9. Lunn M, Fausnight T., Hypersensitivity to total parenteral nutrition fat-emulsion component in an egg-allergic child. Pediatrics. 2011; 128: 1025-1028.
10. Gura KM, Parsons SK, Bechard LJ,. Use of a fish oil-based lipid emulsion to treat essential fatty acid deficiency in a soy allergic patient receiving parenteral nutrition. Clin Nutr. 2005; 24: 839-847.
11. Carpentier Y, Deckelbaum RJ., In vivo handling and metabolism of lipid emulsions. World Rev Nutr Diet. 2015; 112: 57-62.
12. Melin T, Qi C, Bengtsson-Olivecrona G, Akesson B, Nilsson A., Hydrolysis of chylomicron polyenoic fatty acid esters with lipoprotein lipase and hepatic lipase. Biochim Biophys Acta. 1991; 1075: 259-266.
13. Qi K, Seo T, Al-Haideri M,. Omega-3 triglycerides modify blood clearance and tissue targeting pathways of lipid emulsions. Biochemistry. 2002; 41: 3119-3127.
14. Dupont B, Piquet MA, Musikas M, Joubert C, Reimund JM., Use of lipids in home parenteral nutrition. In: Bozzetti F, Staun M, Van Gossum A, eds. CAB International 2015: Home Parenteral Nutrition. 2nd ed. 2015:239-259. Boston, MA: CABI; 2015: 239-259.
15. National Advisory Group on Standards and Practice Guidelines for Parenteral Nutrition. Safe practices for parenteral nutrition formulations. JPEN J Parenter Enteral Nutr. 1998; 22: 49-66.
16. Gianotti L, Meier R, Lobo DN., ESPEN guidelines on parenteral nutrition: pancreas. Clin Nutr. 2009; 28: 428-435.
17. Gura KM, Puder M., Rapid infusion of fish oil-based emulsions in infants does not appear to be associated with fat overload syndrome. Nutr Clin Pract. 2010; 25: 399-402.
18. Vanek VW, Seidner DL, Bistrian B,. A.S.P.E.N. position paper: clinical role for alternative intravenous fat emulsions. Nutr Clin Pract. 2012; 27: 150-192.
19. Singer P, Berger MM, Van de Berghe G,. ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr. 2009; 28: 387-400.
20. Kalfarentzos F, Kokkinis K, Leukaditi K, Maroulis J, Onoufriou A, Alexopoulos K., Comparison between two fat emulsions: Intralipid 30 cent vs intralipid 10 cent in critically ill patients. Clin Nutr. 1998; 17: 31-34.
21. Cavicchi M, Beau P, Crenn P, Degott C, Messing B., Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure. Ann Intern Med. 2000; 132: 525-532.
22. Staun M, Pironi L, Bozzetti F, ESPEN. ESPEN guidelines on parenteral nutrition: home parenteral nutrition (HPN) in adult patients. Clin Nutr. 2009; 28: 467-479.
23. Miles EA, Calder PC., Fatty acids, lipid emulsions and the immune and inflammatory systems. World Rev Nutr Diet. 2015; 112: 17-30.
24. Burrin DG, Ng K, Stoll B, Sáenz De Pipaón M., Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease. Adv Nutr. 2014; 5: 82-91.
25. Llop JM, Virgili N, Moreno-Villares JM,. Phytosterolemia in parenteral nutrition patients: implications for liver disease development. Nutrition. 2008; 24: 1145-1152.
26. Ng K, Stoll B, Chacko S,. Vitamin E in new-generation lipid emulsions protects against parenteral nutrition-associated liver disease in parenteral nutrition-fed preterm pigs. [published online 16, 2015 ]. JPEN J Parenter Enteral Nutr.
27. Puder M, Valim C, Meisel JA,. Parenteral fish oil improves outcomes in patients with parenteral nutrition-associated liver injury. Ann Surg. 2009; 250: 395-402.
28. Gura KM, Lee S, Valim C,. Safety and efficacy of a fish-oil-based fat emulsion in the treatment of parenteral nutrition-associated liver disease. Pediatrics. 2008; 121: 678-686.
29. Goulet O, Antebi H, Wolf C,. A new intravenous fat emulsion containing soybean oil, medium-chain triglycerides, olive oil, and fish oil: a single-center, double-blind randomized study on efficacy and safety in pediatric patients receiving home parenteral nutrition. JPEN J Parenter Enteral Nutr. 2010; 34: 485-495.
30. Seida JC, Mager DR, Hartling L, Vandermeer B, Turner JM., Parenteral ‰-3 fatty acid lipid emulsions for children with intestinal failure and other conditions: a systematic review. JPEN J Parenter Enteral Nutr. 2013; 37: 44-55.
31. Holman RT, Smythe L, Johnson S., Effect of sex and age on fatty acid composition of human serum lipids. Am J Clin Nutr. 1979; 32: 2390-2399.
32. Siguel EN, Chee KM, Gong JX, Schaefer EJ., Criteria for essential fatty acid deficiency in plasma as assessed by capillary column gas-liquid chromatography. Clin Chem. 1987; 33: 1869-1873.
33. Wanten GJA, Calder PC., Immune modulation by parenteral lipid emulsions. Am J Clin Nutr. 2007; 85: 1171-1184.
34. de Meijer VE, Le HD, Meisel JA,. Parenteral fish oil as monotherapy prevents essential fatty acid deficiency in parenteral nutrition-dependent patients. J Pediatr Gastroenterol Nutr. 2010; 50: 212-218.
35. Olthof ED, Roelofs HMJ, Fisk HL, Calder PC, Wanten GJA,. No clinical or biochemical evidence for essential fatty acid deficiency in home patients who depend on long-term olive oil-based parenteral nutrition. [published online 17, 2015 ]. JPEN J Parenter Enteral Nutr.
36. Bigorgne C, Le Tourneau A, Vahedi K,. Sea-blue histiocyte syndrome in bone marrow secondary to total parenteral nutrition. Leuk Lymphoma. 1998; 28: 523-529.
37. Aksnes J, Borsum K, Rollag H,. Intravascular lung macrophages play an essential role in lipid entrapment and the inflammatory tissue reaction seen after long-term lipid-based parenteral nutrition in pigs: an ultrastructural study. APMIS. 1996; 104: 429-436.
38. Lekka ME, Liokatis S, Nathanail C, Galani V, Nakos G., The impact of intravenous fat emulsion administration in acute lung injury. Am J Respir Crit Care Med. 2004; 169: 638-644.
39. Schepens MA, Roelofs HM, Peters WH, Wanten GJ., No evidence for oxidative stress in patients on home parenteral nutrition. Clin Nutr. 2006; 25: 939-948.
40. Lennon C, Davidson KW, Sadowski JA, Mason JB., The vitamin K concentration of intravenous lipid emulsions. JPEN J Parenter Enteral Nutr. 1993; 17: 142-144.
41. The Veterans Affairs Total Parenteral Nutrition Cooperative Study Group. Perioperative total parenteral nutrition in surgical patients. N Engl J Med. 1991; 325: 525-532.
42. Heyland DK, MacDonald S, Keefe L, Drover JW., Total parenteral nutrition in the critically ill patient: a meta-analysis. JAMA. 1998; 280: 2013-2019.
43. Batistella FD, Widergren JT, Andersen JT,. A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition. J Trauma. 1997; 43: 52-58.
44. Pontes-Arruda A, Liu FX, Turpin RS, Mercaldi CJ, Hise M, Zaloga G., Bloodstream infections in patients receiving manufactured parenteral nutrition with vs without lipids: is the use of lipids really deleterious? JPEN J Parenter Enteral Nutr. 2012; 36: 421-430.
45. Olthof ED, Roelofs HM, Versleijen MW,. Long-term olive oil-based parenteral nutrition sustains innate immune function in home patients without active underlying disease. Clin Nutr. 2013; 32: 643-649.
46. Chen B, Zhou Y, Yang P, Wan HW, Wu XT., Safety and efficacy of fish oil-enriched parenteral nutrition regimen on postoperative patients undergoing major abdominal surgery: a meta-analysis of randomized controlled trials. JPEN J Parenter Enteral Nutr. 2010; 34: 387-394.
47. Wei C, Hua J, Bin C, Klassen K., Impact of lipid emulsion containing fish oil on outcomes of surgical patients: systematic review of randomized controlled trials from Europe and Asia. Nutrition. 2010; 26: 474-481.
48. Palmer AJ, Ho CKM, Ajibola O, Avenell A., The role of ‰-3 fatty acid supplemented parenteral nutrition in critical illness in adults: a systematic review and meta-analysis. Crit Care Med. 2013; 1: 307-316.