ESPEN Guidelines on Parenteral Nutrition: Pancreas

Clinical Nutrition

Volumn 28, Issue 4, 2009, Pages 428-435

  Gianotti, L ^a   Meier, R ^b   Lobo, D N ^c   Bassi, C ^d   Dejong, C H C ^e   Ockenga, J ^f   Irtun, O ^g   MacFie, J ^h  

^a SAN GERARDO HOSPITAL   (Italy)

^b Kantonsspital Liestal   (Switzerland)

^c NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d UNIVERSITY OF VERONA   (Italy)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g UNIVERSITY OF TROMSØ   (Norway)

^h UNIVERSITY OF HULL   (United Kingdom)

Author keywords

Acute pancreatitis; Amino acid; Carbohydrate; Substrate metabolism

Indexed keywords

AMINO ACID; ASCORBIC ACID; CARBOHYDRATE; GLUCOSE; GLUTAMINE; LIPID; MULTIVITAMIN; TRACE ELEMENT; TRIACYLGLYCEROL;

ACUTE PANCREATITIS; ANOREXIA; ARTICLE; ARTIFICIAL FEEDING; CHRONIC PANCREATITIS; CLINICAL TRIAL; CRITICAL ILLNESS; DISEASE SEVERITY; DUODENUM STENOSIS; ENTERIC FEEDING; HUMAN; HYPERTRIGLYCERIDEMIA; INJURY; MALNUTRITION; MEDICAL DECISION MAKING; MONITORING; NUTRITIONAL STATUS; NUTRITIONAL SUPPORT; OVERNUTRITION; PANCREAS FUNCTION; PANCREAS SECRETION; PARENTERAL NUTRITION; PRACTICE GUIDELINE; SEPSIS; STOMACH OBSTRUCTION; TREATMENT INDICATION; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; CLINICAL TRIALS AS TOPIC; ENTERAL NUTRITION; GLUTAMINE; HUMANS; HYPERTRIGLYCERIDEMIA; MALNUTRITION; MIDDLE AGED; NUTRITIONAL STATUS; OVERNUTRITION; PANCREATITIS; PANCREATITIS, CHRONIC; PARENTERAL NUTRITION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 68049096193     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2009.04.003     Document Type: Article

References (105)

1. Meier R., Ockenga J., Pertkiewicz M., Pap A., Milinic N., and MacFie J. ESPEN guidelines on enteral nutrition. Clin Nutr 25 2 (2006) 275-284
2. Winsler M.C., Hall C., London N.J.M., and Neoptolemus J.P. Relationship of diagnostic serum amylase to aetiology and prognosis in acute pancreatitis. Gut 33 (1992) 982-986
3. Bradley E.L. Indication for surgery in necrotizing pancreatitis: a millennium review. J Pancreas 1 (2000) 1-3
4. Ashley S.W., Perez A., Pierce E.A., Brooks D.C., Moore Jr. F.D., Whang E.E., et al. Necrotizing pancreatitis. Ann Surg 234 (2001) 572-580
5. Buchler M.W., Gloor B., Muller C.A., Friess H., Seiler C.A., and Uhl W. Acute necrotizing pancreatitis; treatment strategy according to the status of infection. Ann Surg 232 (2000) 619-626
6. Slavin J., Ghaneh P., Sutton R., Hartley M., Rowlands P., Garvey C., et al. Management of necrotizing pancreatitis. World J Gastroenterol 7 (2001) 476-481
7. Flint R., Windsor J., and Bonham M. Trends in the management of severe acute pancreatitis: intervention and outcome. ANZ J Surg 74 (2004) 335-342
8. Karsenti D., Bourlier P., Dorval E., Scotto B., Giraudeau B., Lanotte R., et al. Morbidity and mortality of acute pancreatitis. Prospective study in a French university hospital. Press Med 31 (2002) 727-734
9. Lugli A.K., Carli F., and Wykes L. The importance of nutrition status assessment: the case of severe acute pancreatitis. Nutr Rev 65 7 (2007) 329-334
10. Jolliet P., Pichard C., Biolo G., Chiolero R., Grimble G., Leverve X., et al. Enteral nutrition in intensive care patients: a practical approach. Working Group on Nutrition and Metabolism. European Society of Intensive Care Medicine. Intensive Care Med 24 8 (1998) 848-859
11. Robin A.P., Campbell R., Palani C.K., Liu K., Donahue P.E., and Nyhus L.M. Total parenteral nutrition during acute pancreatitis: clinical experience with 156 patients. World J Surg 14 (1990) 572-579
12. Marik P., and Varon J. The obese patient in the ICU. Chest 113 2 (1998) 492-498
13. Bollen T.L., van Santvoort H.C., Besselink M.G., van Leeuwen M.S., Horvath K.D., Freeny P.C., et al. Dutch Acute Pancreatitis Study Group. The Atlanta classification of acute pancreatitis revisited. Br J Surg 95 1 (2008) 6-21
14. Bouffard Y.N., Delafosse B.X., Annat G.J., Viale J.P., Bertrand D.M., and Motin J.P. Energy expenditure during severe acute pancreatitis. J Parenter Enteral Nutr 13 (1989) 26-29
15. Sitzmann J.V., Steinborn P.A., Zinner M.J., and Cameron J.L. Total parenteral nutrition and alternative energy substrates in treatment of severe acute pancreatitis. Am J Surg 127 (1974) 196-200
16. Shaw J.H., and Wolfe R.R. Glucose, fatty acids and urea kinetics in patients with severe pancreatitis. The response to substrate infusion and total parenteral nutrition. Ann Surg 204 (1986) 665-672
17. Variyam E.P., Fuller R.K., Brown F.M., and Quallich L.G. Effect of parenteral amino acids on human pancreatic secretion. Dig Dis Sci 30 (1985) 541-546
18. Niederau C., Sonnerberg A., and Erckenbrecht J. Effect of intravenous infusion of amino acids, fat, or glucose on unstimulated pancreatic secretion in healthy humans. Dig Dis Sci 30 (1985) 445-455
19. Furst P., Pogan K., and Stehle P. Glutamine dipeptides in clinical nutrition. Nutrition 13 (1997) 731-737
20. Novak F., Heyland D.K., Avenell A., Drover J.W., and Su X. Glutamine supplementation in serious illness: a systematic review of the evidence. Crit Care Med 30 9 (2002 Sep) 2022-2029
21. Dechelotte P., Hasselmann M., Cynober L., Allaouchiche B., Coeffier M., Hecketsweiler B., et al. l-Alanyl-l-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. Crit Care Med 34 3 (2006 Mar) 598-604
22. Ockenga J., Borchert K., Rifai K., Manns M.P., and Bischoff S.C. Effect of glutamine-enriched total parenteral nutrition in patients with acute pancreatitis. Clin Nutr 21 (2002) 409-416
23. de Beaux A.C., O'Riordain M.G., Ross J.A., Jodozi L., Carter D.C., and Fearon K.C. Glutamine-supplemented total parenteral nutrition reduces blood mononuclear cell interleukin-8 release in severe acute pancreatitis. Nutrition 14 (1998) 261-265
24. Zhao G., Wang C.Y., Wang F., and Xiong J.X. Clinical study on nutrition support in patients with severe acute pancreatitis. World J Gastroenterol 9 (2003) 2105-2108
25. McClave S., Chang W., Dhaliwal R., and Heyland D.K. Nutrition support in acute pancreatitis: a systematic review of the literature. JPEN J Parenter Enteral Nutr 30 2 (2006) 143-156
26. Xian-Li H., Qing-Jiu M., Jang-Guo L., Yan-Kui C., and Xi-Lin D. Effect of total parenteral nutrition with and without glutamine dipeptide supplementation on outcome in severe acute pancreatitis. Clin Nutr Suppl 1 (2004) 43-47
27. Sahin H., Mercanligil S.M., Inanç N., and Ok E. Effects of glutamine-enriched total parenteral nutrition on acute pancreatitis. Eur J Clin Nutr 61 12 (2007) 1429-1434
28. Fuentes-Orozco C., Cervantes-Guevara G., Muciño-Hernández I., López-Ortega A., Ambriz-González G., Gutiérrez-de-la-Rosa J.L., et al. l-Alanyl-l-glutamine-supplemented parenteral nutrition decreases infectious morbidity rate in patients with severe acute pancreatitis. JPEN J Parenter Enteral Nutr 32 (2008) 403-411
29. Xue P., Deng L.H., Xia Q., Zhang Z.D., Hu W.M., Yang X.N., et al. Impact of alanyl-glutamine dipeptide on severe acute pancreatitis in early stage. World J Gastroenterol 14 (2008) 474-478
30. ASPEN Board of Directors and the Clinical Guidelines Task Force. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. JPEN J Parenter Enteral Nutr 26 1 Suppl (2002) 1SA-138SA
31. Klein E., Shnebaum S., Ben-Ari G., and Dreiling D.A. Effect of total parenteral nutrition on exocrine pancreatic secretion. Am J Gastroenterol 78 (1983) 31-33
32. Lam W.F., Masclee A.A., de Boer S.Y., Souverijin J.N., and Larners C.B. Effect of acute hyperglycemia on basal and cholecystokinin-stimulated exocrine pancreatic secretion in humans. Life Sci 60 (1997) 2183-2190
33. Martinez J.L., Castilla M.S., Velasco P.J., et al. Non-glucose carbohydrates in parenteral nutrition of patients with a systemic inflammatory response syndrome. Nutr Hosp 14 (1999) 71-80
34. Greenberger N.J. Pancreatitis and hyperlipemia. N Engl J Med 289 (1973) 586-587
35. Yadav D., and Pitchomoni C.S. Issues in hyperlipidemic pancreatitis. J Clin Gatroenterol 36 1 (2003) 54-62
36. Rollan A., Guzman S., Pimental F., and Nervi F. Catabolism of chylomicron remnants in patients with previous acute pancreatitis. Gastroenterology 98 (1990) 1649-1654
37. Cameron J.L., Capuzzi D.M., Zuidema G.D., and Margolis S. Acute pancreatitis with hyperlipidemia: evidence for a persistent defect in lipid metabolism. Am J Med 56 (1974) 482-487
38. Guzman S., Nervi F., Llanos O., Leon P., and Valdivieso V. Impaired lipid clearance in patients with previous acute pancreatitis. Gut 26 (1985) 888-897
39. Dominguez-Munoz J.E., Junemann F., and Malfertheiner P. Hyperlipidemia in acute pancreatitis. Cause or epiphenomenon? Int J Pancreatol 18 (1995) 101-106
40. Haber P.S., Wilson J.S., Apte M.V., Hall W., Goumas K., and Pirola R.C. Lipid tolerance does not account for susceptibility to alcoholic and gall-stone pancreatitis. Gastroenterology 106 (1994) 742-748
41. Buch A., Buch J., Carlsen A., and Schmidt A. Hyperlipemia and pancreatitis. World J Surg 4 (1980) 307-314
42. Dominguez-Munoz J.E., Malferteiner P., Ditschuneit H.H., et al. Hyperlipidemia in acute pancreatitis: relationship with etiology, onset and severity of the disease. Int J Pancreatol 10 (1991) 261-267
43. Rouis M., Lohse P., Dugi K.A., Loshe P., Beg O.U., Ronan R., et al. Homozygosity for two point mutations in the lipoprotein lipase (LPL) gene in patient with familial LPL deficiency: LPL (Asp9 → Asn, Tyr262 → His). J Lipid Res 37 (1996) 651-661
44. Jap T.S., Jenq S.F., Wu Y.C., and Chung H.M. Mutations in the lipoprotein lipase gene as a cause of hypertriglyceridemia and pancreatitis in Taiwan. Pancreas 27 (2003) 122-126
45. Meier R., Beglinger C., Layer P., Gullo L., Keim V., Laugier R., et al. ESPEN guidelines on nutrition in acute pancreatitis. European Society of Parenteral and Enteral Nutrition. Clin Nutr 21 2 (2002) 173-183
46. Burns G.P., and Stein T.A. Pancreatic enzyme secretion during intravenous fat infusion. J Parenter Enteral Nutr 11 (1987) 60-62
47. Fried G.M., Ogden W.D., Rhea A., Greeley G., and Thompson J.C. Pancreatic protein secretion and gastrointestinal hormone release in response to parenteral amino acids and lipid in dogs. Surgery 92 5 (1982) 902-905
48. Konturek S.J., Tasler J., Cieszkowski M., Jaworek J., and Konturek J. Intravenous amino acids and fats stimulate pancreatic secretion. Am J Physiol 233 (1979) E678-E684
49. Stabile B.E., Borzatta M., Stubbs R.S., and Debas H.T. Intravenous mixed amino acids and fats do not stimulate exocrine pancreatic secretion. J Physiol 246 (1884) G274-G280
50. Stabile B.E., and Debas H.T. Intravenous versus intraduodenal amino acids, fats and glucose as stimulants of pancreatic secretion. Surg Forum 32 (1981) 224-226
51. EdelMann K., and Valenzuela J.E. Effect of intravenous lipid on human pancreatic secretion. Gastroenterology 85 (1983) 1063-1068
52. Chait A., and Brunzell J.D. Chylomicronemia syndrome. Adv Intern Med 37 (1992) 249-273
53. Toskess P.P. Hyperlipidemic pancreatitis. Gastroenterol Clin North Am 19 4 (1990) 783-791
54. Farmer R.G., Winkelman E.I., Brown H.B., and Lewis L.A. Hyperlipoproteinemia and pancretitis. Am J Med 54 (1973) 161-174
55. Havel R.J. Pathogenesis, differentiation and management of hypertriglyceridemia. Adv Intern Med 15 (1969) 117-154
56. Searles G., and Ooi T.C. Underrecognition of chylomicronemia as a cause of acute pancreatitis. Can Med Assoc J 147 (1992) 1806-1808
57. Ranson J.H.C., Rifkind K.M., Roses D.F., Fink S.D., Eng K., and Localio S.A. Objective early identification of severe acute pancreatitis. Am J Gastroenterol 61 (1974) 443-451
58. Ranson J.H.C., Rifkind K.M., Roses D.F., Fink S.D., Eng K., and Spencer F.C. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet 139 (1974) 69-81
59. Amann S.T., and Toskes P.P. Hyperlipidemia and acute pancreatitis. In: Beger H.G., Warshaw A.L., Carr-Locke D., Russell C., Buchler M.W., Neoptolemos J.P., and Sarr M.G. (Eds). The pancreas (1998), Hardcover-Blackwell Publishers 311-316
60. Piolot A., Nadler F., Cavallero E., Coquard J.L., and Jacotot B. Prevention of recurrent acute pancreatitis in patients with severe HTG: value of regular plasmapheresis. Pancreas 13 (1996) 96-99
61. Archad J.M., Westeel P.F., Moriniere J.D., Lalau J.D., de Cagny B., and Fournier A. Pancreatitis related to severe acute HTG during pregnancy: treatment with lipoprotein apheresis. Intensive Care Med 17 (1991) 236-237
62. Roberts I.M. Hyperlipidemic gestational pancreatitis. Gastroenterology 104 (1993) 1560-1562
63. Adamkin D.H., Gelke K.N., and Andrews B.F. Fat emulsions and hypertriglyceridemia. JPEN J Parenter Enteral Nutr 8 (1984) 563-567
64. Wang X., Li W., Li N., and Li J. Omega-3 fatty acids-supplemented parenteral nutrition decreases hyperinflammatory response and attenuates systemic disease sequelae in severe acute pancreatitis: a randomized and controlled study. JPEN J Parenter Enteral Nutr 32 3 (2008) 236-241
65. Du W.D., Yuan Z.R., Sun J., Tang J.X., Cheng A.Q., Shen D.M., et al. Therapeutic efficacy of high-dose vitamin C on acute pancreatitis and its potential mechanisms. World J Gastroenterol 9 (2003) 2565-2569
66. Virlos I.T., Mason J., Schofield D., McCloy R.F., Eddleston J.M., and Siriwardena A.K. Intravenous n-acetylcysteine, ascorbic acid and selenium-based anti-oxidant therapy in severe acute pancreatitis. Scand J Gastroenterol 38 (2003) 1262-1267
67. Siriwardena A.K., Mason J.M., Balachandra S., Bagul A., Galloway S., Formela L., et al. Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis. Gut 56 10 (2007) 1439-1444
68. Niederau C., Sonnenberg A., and Erckenbrecht J. Effects of intravenous infusion of amino acids, fat, or glucose on unstimulated pancreatic secretion in healthy humans. Dig Dis Sci 30 5 (1985) 445-455
69. Stabile B.E., Borzatta M., and Stubbs R.S. Pancreatic secretory responses to intravenous hyperalimentation and intraduodenal elemental and full liquid diets. JPEN J Parenter Enteral Nutr 8 4 (1984) 377-380
70. Fan B.G., Salehi A., Sternby B., Axelson J., Lundquist I., Andren-Sandberg A., et al. Total parenteral nutrition influences both endocrine and exocrine function of rat pancreas. Pancreas 15 2 (1997) 147-153
71. Sax H.C., Warner B.W., Talamini M.A., Hamilton F.N., Bell Jr. R.H., Fischer J.E., et al. Early total parenteral nutrition in acute pancreatitis: lack of beneficial effects. Am J Surg 153 (1987) 117-123
72. Petrov M.S., van Santvoort H.C., Besselink M.G., Cirkel G.A., Brink M.A., and Gooszen H.G. Oral refeeding after onset of acute pancreatitis: a review of literature. Am J Gastroenterol 102 9 (2007) 2079-2084
73. Besselink M.G., van Santvoort H.C., Buskens E., Boermeester M.A., van Goor H., Timmerman H.M., et al. Probiotic prophylaxis in patients with predicted severe acute pancreatitis: a randomized, double-blind, placebo-controlled trial. Lancet 371 (2008) 651-659
74. Curtis C.S., and Kudsk K.A. Nutrition support in pancreatitis. Surg Clin North Am 87 6 (2007) 1403-1415
75. O'Keefe S.J., and Sharma S. Nutrition support in severe acute pancreatitis. Gastroenterol Clin North Am 36 2 (2007) 297-312
76. Thomson A. Enteral versus parenteral nutritional support in acute pancreatitis: a clinical review. J Gastroenterol Hepatol 21 (2006) 22-25
77. Dervenis C., Smailis D., and Hatzitheoklitos E. Bacterial translocation and its prevention in acute pancreatitis. J Hepatobiliary Pancreat Surg 10 6 (2003) 415-418
78. Gianotti L., Munda R., Gennari R., Pyles R., and Alexander J.W. Effect of different regimens of gut decontamination on bacterial translocation and mortality in experimental acute pancreatitis. Eur J Surg 161 (1995 Feb) 85-92
79. Lobo D.N., Memon M.A., Allison S.P., and Rowlands B.J. Evolution of nutritional support in acute pancreatitis. Br J Surg 87 (2000) 695-707
80. Powell J.J., Murchison J.T., Fearon K.C., Ross J.A., and Siriwardena A.K. Randomized controlled trial of the effect of early enteral nutrition on markers of the inflammatory response in predicted severe acute pancreatitis. Br J Surg 87 (2000) 1375-1381
81. Kumar, Singh N., Prakash S., Saraya A., and Joshi Y.K. Early enteral nutrition in severe acute pancreatitis: a prospective randomized controlled trial comparing nasojejunal and nasogastric routes. J Clin Gastroenterol 40 5 (2006) 431-434
82. Eatock F.C., Chong P., Menezes N., Murray L., McKay C.J., Carter C.R., et al. A randomized study of early nasogastric versus nasojejunal feeding in severe acute pancreatitis. Am J Gastroenterol 100 2 (2005) 432-439
83. Eatock F.C., Brombacher G.D., Steven A., Imrie C.W., McKay C.J., and Carter R. Nasogastric feeding in severe acute pancreatitis may be practical and safe. Int J Pancreatol 28 1 (2000) 23-29
84. Eckerwall G.E., Axelsson J.B., and Andersson R.G. Early nasogastric feeding in predicted severe acute pancreatitis: a clinical, randomized study. Ann Surg 244 6 (2006) 959-965
85. Tesinsky P. Nutritional care of pancreatitis and its complications. Curr Opin Clin Nutr Metab Care 2 (1999) 395-398
86. Sun B., Gao Y., Xu J., Zhou X.L., Zhou Z.Q., Liu C., et al. Role of individually staged nutritional support in the management of severe pancreatitis. Hepatobiliary Pancreat Dis Int 3 (2004) 458-463
87. Meier R., and Beglinger C. Nutrition in pancreatic diseases. Best Pract Res Clin Gastroenterol 20 (2006) 507-529
88. De Waele J.J., Hoste E., Blot S.I., Decruyenaere J., and Colardyn F. Intra-abdominal hypertension in patients with severe acute pancreatitis. Crit Care 9 (2005) R452-R457
89. Cheatham M.L., Malbrain M.L., Kirkpatrick A., Sugrue M., Parr M., De Waele J., et al. Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations. Intensive Care Med 33 (2007) 951-962
90. Rosas J.M., Soto S.N., Aracil J.S., Cladera P.R., Borlan R.H., Sanchez A.V., et al. Intra-abdominal pressure as a marker of severity in acute pancreatitis. Surgery 141 (2007) 173-178
91. Cothren C.C., Moore E.E., Ciesla D.J., Johnson J.L., Moore J.B., Haenel J.B., et al. Postinjury abdominal compartment syndrome does not preclude early enteral feeding after definitive closure. Am J Surg 188 (2004) 653-658
92. Marvin R.G., McKinley B.A., McQuiggan M., Cocanour C.S., and Moore F.A. Nonocclusive bowel necrosis occurring in critically ill trauma patients receiving enteral nutrition manifests no reliable clinical signs for early detection. Am J Surg 179 (2000) 7-12
93. Miller J.A., Singireddy S., Maldjian P., and Baker S.R. A reevaluation of the radiographically detectable complications of percutaneous venous access lines inserted by four subcutaneous approaches. Am Surg 65 (1999) 125-130
94. May J., Murchan P., MacFie J., Sedman P., Donat R., Palmer D., et al. Prospective study of the aetiology of infusion phlebitis and line failure during peripheral parenteral nutrition. Br J Surg 83 (1996) 1091-1094
95. Culebras J.M., Martin-Pena G., Garcia-de-Lorenzo A., Zarazaga A., and Rodriguez-Montes J.A. Practical aspects of peripheral parenteral nutrition. Curr Opin Clin Nutr Metab Care 7 (2004) 303-307
96. Dejong C.H., Greve J.W., and Soeters P.B. Nutrition in patients with acute pancreatitis. Curr Opin Crit Care 7 4 (2001) 251-256
97. Schneider P.J. Nutrition support teams: an evidence-based practice. Nutr Clin Pract 21 1 (2006) 62-67
98. O'Grady N.P., Alexander M., Dellinger E.P., Gerberding J.L., Heard S.O., Maki D.G., et al. Healthcare Infection Control Practices Advisory Committee. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control 30 (2002) 476-489
99. Crook M.A., Hally V., and Panteli J.V. The importance of the refeeding syndrome. Nutrition 17 (2001) 632-637
100. Kraft M.D., Btaiche I.F., and Sacks G.S. Review of the refeeding syndrome. Nutr Clin Pract 20 (2005) 625-633
101. van den Berghe G., Wouters P., Weekers F., Verwaest C., Bruyninckx F., Schetz M., et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 345 (2001) 1359-1367
102. Van den Berghe G., Wilmer A., Hermans G., Meersseman W., Wouters P.J., Milants I., et al. Intensive insulin therapy in the medical ICU. N Engl J Med 354 5 (2006) 449-461
103. Vanhorebeek I., Langouche L., and Van den Berghe G. Tight blood glucose control with insulin in the ICU: facts and controversies. Chest 132 1 (2007) 268-278
104. Marik P.E., and Varon J. Intensive insulin therapy in the ICU: is it now time to jump off the bandwagon?. Resuscitation 74 1 (2007) 191-193
105. Jeejeebhoy K.N. Total parenteral nutrition: potion or poison?. Am J Clin Nutr 74 2 (2001) 160-163