Transcription factor Egr1 is involved in high glucose-induced proliferation and fibrosis in rat glomerular mesangial cells

Cellular Physiology and Biochemistry

Volumn 36, Issue 6, 2015, Pages 2093-2107

  Wang, Dan ^a   Guan, Mei Ping ^a   Zheng, Zong Ji ^a   Li, Wen Qi ^a   Lyv, Fu Ping ^a   Pang, Ruo Yu ^a   Xue, Yao Ming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Egr1; Extracellular matrix; Mesangial cells; TGF 1

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; COLLAGEN TYPE 4; EARLY GROWTH RESPONSE FACTOR 1; FIBRONECTIN; GLUCOSE; LAMININ; MANNITOL; PERLECAN; TRANSFORMING GROWTH FACTOR BETA1; EGR1 PROTEIN, RAT; PROTEIN BINDING; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAPILLARY BASEMENT MEMBRANE; CELL CULTURE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; GLOMERULAR MESANGIAL CELL; GLOMERULUS BASEMENT MEMBRANE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPEROSMOTIC STRESS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; MESANGIUM CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; GLOMERULUS; METABOLISM; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PATHOLOGY;

RATTUS;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; COLLAGEN TYPE IV; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; EARLY GROWTH RESPONSE PROTEIN 1; EXTRACELLULAR MATRIX; FIBRONECTINS; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSE; KIDNEY GLOMERULUS; MESANGIAL CELLS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS, INBRED OLETF; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84939606120     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430177     Document Type: Article

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