Global Gene Expression Profiling in PAI-1 Knockout Murine Heart and Kidney: Molecular Basis of Cardiac-Selective Fibrosis

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Ghosh, Asish K ^a   Murphy, Sheila B ^a   Kishore, Raj ^a   Vaughan, Douglas E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; ANKYRIN DOMAIN 1; EARLY GROWTH RESPONSE FACTOR 1; KLOTHO PROTEIN; KRUPPEL LIKE FACTOR 6; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE INHIBITOR; PROTEINASE INHIBITOR 16; SOMATOMEDIN BINDING PROTEIN 6; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UROKINASE; ANKRD1 PROTEIN, MOUSE; EGR1 PROTEIN, MOUSE; LEUKOCYTE ELASTASE INHIBITOR; MUSCLE PROTEIN; NUCLEAR PROTEIN; PROTEASE INHIBITOR 16, MOUSE; REPRESSOR PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE-4;

ANIMAL CELL; ANIMAL TISSUE; ANKYRIN REPEAT DOMAIN 1 GENE; ARTICLE; CARDIAC SELECTIVE FIBROSIS; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; D SITE ALBUMIN PROMOTER BINDING PROTEIN GENE; DOWN REGULATION; EARLY GROWTH RESPONSE 1 GENE; GENE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HEART; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; IMMUNITY; IN VITRO STUDY; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 6 GENE; INTRACELLULAR SIGNALING; KIDNEY; KLOTHO GENE; KNOCKOUT MOUSE; KRUPPEL LIKE FACTOR 6 GENE; LYSYL OXIDASE LIKE 1 GENE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PLASMINOGEN ACTIVATOR INHIBITOR 1 GENE; PROTEASE INHIBITOR 16 GENE; SCLERAXIS GENE; STRESS; TISSUE INHIBITOR OF METALLOPROTEINASE 1 GENE; TISSUE INHIBITOR OF METALLOPROTEINASE 2 GENE; TRANSCRIPTION REGULATION; UPREGULATION; WILD TYPE; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CLUSTER ANALYSIS; DEFICIENCY; DRUG EFFECTS; ENDOTHELIUM CELL; FIBROSIS; GENETICS; HEART MUSCLE; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION; REPRODUCIBILITY;

MURINAE; MUS;

ANIMALS; CLUSTER ANALYSIS; EARLY GROWTH RESPONSE PROTEIN 1; ENDOTHELIAL CELLS; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; KIDNEY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE PROTEINS; MYOCARDIUM; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMERASE CHAIN REACTION; PROTEINASE INHIBITORY PROTEINS, SECRETORY; REPRESSOR PROTEINS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSFORMING GROWTH FACTOR BETA;

EID: 84878422265     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063825     Document Type: Article

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