메뉴 건너뛰기




Volumn 36, Issue 8, 2015, Pages 451-459

Chronic inflammation and the development of malignancy in the GI tract

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; STAT3 PROTEIN;

EID: 84939563329     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2015.06.007     Document Type: Review
Times cited : (48)

References (65)
  • 1
    • 33748105839 scopus 로고    scopus 로고
    • The contribution of Rudolf Virchow to the concept of inflammation: what is still of importance?
    • Heidland A., et al. The contribution of Rudolf Virchow to the concept of inflammation: what is still of importance?. J. Nephrol. 2006, 19(Suppl. 10):S102-S109.
    • (2006) J. Nephrol. , vol.19 , pp. S102-S109
    • Heidland, A.1
  • 2
    • 84873412849 scopus 로고    scopus 로고
    • Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development
    • Azer S.A. Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development. Eur. J. Gastroenterol. Hepatol. 2013, 25:271-281.
    • (2013) Eur. J. Gastroenterol. Hepatol. , vol.25 , pp. 271-281
    • Azer, S.A.1
  • 3
    • 84878889056 scopus 로고    scopus 로고
    • ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation
    • Myant K.B., et al. ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. Cell Stem Cell 2013, 12:761-773.
    • (2013) Cell Stem Cell , vol.12 , pp. 761-773
    • Myant, K.B.1
  • 4
    • 79955585058 scopus 로고    scopus 로고
    • Cytokines, inflammation and colon cancer
    • Klampfer L. Cytokines, inflammation and colon cancer. Curr. Cancer Drug Targets 2011, 11:451-464.
    • (2011) Curr. Cancer Drug Targets , vol.11 , pp. 451-464
    • Klampfer, L.1
  • 5
    • 0038352053 scopus 로고    scopus 로고
    • Radical causes of cancer
    • Hussain S.P., et al. Radical causes of cancer. Nat. Rev. Cancer 2003, 3:276-285.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 276-285
    • Hussain, S.P.1
  • 6
    • 72949119310 scopus 로고    scopus 로고
    • Complex landscapes of somatic rearrangement in human breast cancer genomes
    • Stephens P.J., et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009, 462:1005-1010.
    • (2009) Nature , vol.462 , pp. 1005-1010
    • Stephens, P.J.1
  • 7
    • 79751489596 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer
    • Fearon E.R. Molecular genetics of colorectal cancer. Annu. Rev. Pathol. 2011, 6:479-507.
    • (2011) Annu. Rev. Pathol. , vol.6 , pp. 479-507
    • Fearon, E.R.1
  • 8
    • 0346606862 scopus 로고    scopus 로고
    • Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease
    • Hussain S.P., et al. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res. 2000, 60:3333-3337.
    • (2000) Cancer Res. , vol.60 , pp. 3333-3337
    • Hussain, S.P.1
  • 9
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: linkage with somatic hypermutation
    • Honjo T., et al. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu. Rev. Immunol. 2002, 20:165-196.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 165-196
    • Honjo, T.1
  • 10
    • 50349093233 scopus 로고    scopus 로고
    • The AID/APOBEC family of nucleic acid mutators
    • Conticello S.G. The AID/APOBEC family of nucleic acid mutators. Genome Biol. 2008, 9:229.
    • (2008) Genome Biol. , vol.9 , pp. 229
    • Conticello, S.G.1
  • 11
    • 34147180434 scopus 로고    scopus 로고
    • Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
    • Matsumoto Y., et al. Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat. Med. 2007, 13:470-476.
    • (2007) Nat. Med. , vol.13 , pp. 470-476
    • Matsumoto, Y.1
  • 12
    • 51249087746 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers
    • Endo Y., et al. Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology 2008, 135:889-898.
    • (2008) Gastroenterology , vol.135 , pp. 889-898
    • Endo, Y.1
  • 13
    • 84859426818 scopus 로고    scopus 로고
    • Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation
    • Takai A., et al. Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation. Oncogene 2012, 31:1733-1742.
    • (2012) Oncogene , vol.31 , pp. 1733-1742
    • Takai, A.1
  • 14
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones P.A., Baylin S.B. The epigenomics of cancer. Cell 2007, 128:683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 15
    • 0033404952 scopus 로고    scopus 로고
    • Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production
    • Hmadcha A., et al. Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production. J. Exp. Med. 1999, 190:1595-1604.
    • (1999) J. Exp. Med. , vol.190 , pp. 1595-1604
    • Hmadcha, A.1
  • 16
    • 11244257034 scopus 로고    scopus 로고
    • Decreased fidelity in replicating CpG methylation patterns in cancer cells
    • Ushijima T., et al. Decreased fidelity in replicating CpG methylation patterns in cancer cells. Cancer Res. 2005, 65:11-17.
    • (2005) Cancer Res. , vol.65 , pp. 11-17
    • Ushijima, T.1
  • 17
    • 51449106521 scopus 로고    scopus 로고
    • KRAS mutations predict response to EGFR inhibitors
    • Raponi M., et al. KRAS mutations predict response to EGFR inhibitors. Curr. Opin. Pharmacol. 2008, 8:413-418.
    • (2008) Curr. Opin. Pharmacol. , vol.8 , pp. 413-418
    • Raponi, M.1
  • 18
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson S.M., et al. RAS is regulated by the let-7 microRNA family. Cell 2005, 120:635-647.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1
  • 19
    • 44649099646 scopus 로고    scopus 로고
    • Regulation of Wnt signaling by the nuclear pore complex
    • Shitashige M., et al. Regulation of Wnt signaling by the nuclear pore complex. Gastroenterology 2008, 134:1961-1971.
    • (2008) Gastroenterology , vol.134 , pp. 1961-1971
    • Shitashige, M.1
  • 20
    • 41349091246 scopus 로고    scopus 로고
    • Wnt signaling inside the nucleus
    • Shitashige M., et al. Wnt signaling inside the nucleus. Cancer Sci. 2008, 99:631-637.
    • (2008) Cancer Sci. , vol.99 , pp. 631-637
    • Shitashige, M.1
  • 21
    • 78651241644 scopus 로고    scopus 로고
    • Colorectal cancer molecular biology moves into clinical practice
    • Pritchard C.C., Grady W.M. Colorectal cancer molecular biology moves into clinical practice. Gut 2011, 60:116-129.
    • (2011) Gut , vol.60 , pp. 116-129
    • Pritchard, C.C.1    Grady, W.M.2
  • 22
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser A.R., et al. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990, 247:322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1
  • 23
    • 34447296425 scopus 로고    scopus 로고
    • Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
    • Rakoff-Nahoum S., Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 2007, 317:124-127.
    • (2007) Science , vol.317 , pp. 124-127
    • Rakoff-Nahoum, S.1    Medzhitov, R.2
  • 24
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • Neufert C., et al. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat. Protoc. 2007, 2:1998-2004.
    • (2007) Nat. Protoc. , vol.2 , pp. 1998-2004
    • Neufert, C.1
  • 25
    • 27644468268 scopus 로고    scopus 로고
    • How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men
    • Corpet D.E., Pierre F. How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men. Eur. J. Cancer 2005, 41:1911-1922.
    • (2005) Eur. J. Cancer , vol.41 , pp. 1911-1922
    • Corpet, D.E.1    Pierre, F.2
  • 26
    • 0032516640 scopus 로고    scopus 로고
    • Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility
    • Papanikolaou A., et al. Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility. Cancer Lett. 1998, 130:29-34.
    • (1998) Cancer Lett. , vol.130 , pp. 29-34
    • Papanikolaou, A.1
  • 27
    • 0031837999 scopus 로고    scopus 로고
    • Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice
    • Papanikolaou A., et al. Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice. Toxicol. Appl. Pharmacol. 1998, 150:196-203.
    • (1998) Toxicol. Appl. Pharmacol. , vol.150 , pp. 196-203
    • Papanikolaou, A.1
  • 28
    • 84896336619 scopus 로고    scopus 로고
    • Mesenchymal stem cells cancel azoxymethane-induced tumor initiation
    • Nasuno M., et al. Mesenchymal stem cells cancel azoxymethane-induced tumor initiation. Stem Cells 2014, 32:913-925.
    • (2014) Stem Cells , vol.32 , pp. 913-925
    • Nasuno, M.1
  • 29
    • 0034122380 scopus 로고    scopus 로고
    • Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane
    • Takahashi M., et al. Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane. Carcinogenesis 2000, 21:1117-1120.
    • (2000) Carcinogenesis , vol.21 , pp. 1117-1120
    • Takahashi, M.1
  • 30
    • 77953719563 scopus 로고    scopus 로고
    • Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: a potential colorectal cancer chemopreventative
    • Westley C.B., et al. Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: a potential colorectal cancer chemopreventative. Cancer Biol. Ther. 2010, 9:371-379.
    • (2010) Cancer Biol. Ther. , vol.9 , pp. 371-379
    • Westley, C.B.1
  • 31
    • 18544367348 scopus 로고    scopus 로고
    • Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours
    • Hu Y., et al. Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours. Int. J. Cancer 2005, 115:561-567.
    • (2005) Int. J. Cancer , vol.115 , pp. 561-567
    • Hu, Y.1
  • 32
    • 84872370561 scopus 로고    scopus 로고
    • Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors
    • Schwitalla S., et al. Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors. Cancer Cell 2013, 23:93-106.
    • (2013) Cancer Cell , vol.23 , pp. 93-106
    • Schwitalla, S.1
  • 33
    • 84886928127 scopus 로고    scopus 로고
    • Non-melanoma skin cancer in mouse and man
    • Schwarz M., et al. Non-melanoma skin cancer in mouse and man. Arch. Toxicol. 2013, 87:783-798.
    • (2013) Arch. Toxicol. , vol.87 , pp. 783-798
    • Schwarz, M.1
  • 34
    • 79959369355 scopus 로고    scopus 로고
    • Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
    • Normand S., et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:9601-9606.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 9601-9606
    • Normand, S.1
  • 35
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • Grivennikov S., et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 2009, 15:103-113.
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1
  • 36
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S., et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat. Med. 2009, 15:1016-1022.
    • (2009) Nat. Med. , vol.15 , pp. 1016-1022
    • Wu, S.1
  • 37
    • 84858156041 scopus 로고    scopus 로고
    • Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations
    • Han W., Lo H.W. Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations. Cancer Lett. 2012, 318:124-134.
    • (2012) Cancer Lett. , vol.318 , pp. 124-134
    • Han, W.1    Lo, H.W.2
  • 38
    • 0032518375 scopus 로고    scopus 로고
    • Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
    • Boccaccio C., et al. Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. Nature 1998, 391:285-288.
    • (1998) Nature , vol.391 , pp. 285-288
    • Boccaccio, C.1
  • 39
    • 58649101347 scopus 로고    scopus 로고
    • Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
    • Bollrath J., et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 2009, 15:91-102.
    • (2009) Cancer Cell , vol.15 , pp. 91-102
    • Bollrath, J.1
  • 40
    • 84907879855 scopus 로고    scopus 로고
    • Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration
    • Phesse T.J., et al. Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration. Sci. Signal. 2014, 7:ra92.
    • (2014) Sci. Signal. , vol.7 , pp. 92
    • Phesse, T.J.1
  • 41
    • 5644252874 scopus 로고    scopus 로고
    • TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
    • Becker C., et al. TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 2004, 21:491-501.
    • (2004) Immunity , vol.21 , pp. 491-501
    • Becker, C.1
  • 42
  • 43
    • 0041677606 scopus 로고    scopus 로고
    • Principles of interleukin (IL)-6-type cytokine signalling and its regulation
    • Heinrich P.C., et al. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 2003, 374:1-20.
    • (2003) Biochem. J. , vol.374 , pp. 1-20
    • Heinrich, P.C.1
  • 44
    • 84896495700 scopus 로고    scopus 로고
    • Master regulator of intestinal disease: IL-6 in chronic inflammation and cancer development
    • Waldner M.J., et al. Master regulator of intestinal disease: IL-6 in chronic inflammation and cancer development. Semin. Immunol. 2014, 26:75-79.
    • (2014) Semin. Immunol. , vol.26 , pp. 75-79
    • Waldner, M.J.1
  • 45
    • 84868159001 scopus 로고    scopus 로고
    • Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease
    • Chalaris A., et al. Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease. Dig. Dis. 2012, 30:492-499.
    • (2012) Dig. Dis. , vol.30 , pp. 492-499
    • Chalaris, A.1
  • 46
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation
    • Iliopoulos D., et al. An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 2009, 139:693-706.
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1
  • 47
    • 84881534116 scopus 로고    scopus 로고
    • Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically
    • Putoczki T.L., et al. Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically. Cancer Cell 2013, 24:257-271.
    • (2013) Cancer Cell , vol.24 , pp. 257-271
    • Putoczki, T.L.1
  • 48
    • 43049096401 scopus 로고    scopus 로고
    • STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
    • Ernst M., et al. STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J. Clin. Invest. 2008, 118:1727-1738.
    • (2008) J. Clin. Invest. , vol.118 , pp. 1727-1738
    • Ernst, M.1
  • 49
    • 84868613705 scopus 로고    scopus 로고
    • Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
    • Grivennikov S.I., et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012, 491:254-258.
    • (2012) Nature , vol.491 , pp. 254-258
    • Grivennikov, S.I.1
  • 50
    • 70350400863 scopus 로고    scopus 로고
    • New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain
    • Dumoutier L., et al. New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain. J. Biol. Chem. 2009, 284:26377-26384.
    • (2009) J. Biol. Chem. , vol.284 , pp. 26377-26384
    • Dumoutier, L.1
  • 51
    • 84902077790 scopus 로고    scopus 로고
    • The role of the IL-22/IL-22R1 axis in cancer
    • Lim C., Savan R. The role of the IL-22/IL-22R1 axis in cancer. Cytokine Growth Factor Rev. 2014, 25:257-271.
    • (2014) Cytokine Growth Factor Rev. , vol.25 , pp. 257-271
    • Lim, C.1    Savan, R.2
  • 52
    • 84879571464 scopus 로고    scopus 로고
    • Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
    • Kirchberger S., et al. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J. Exp. Med. 2013, 210:917-931.
    • (2013) J. Exp. Med. , vol.210 , pp. 917-931
    • Kirchberger, S.1
  • 53
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L., et al. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J. Exp. Med. 2009, 206:1457-1464.
    • (2009) J. Exp. Med. , vol.206 , pp. 1457-1464
    • Wang, L.1
  • 54
    • 33847351136 scopus 로고    scopus 로고
    • The JAK-STAT signaling pathway: input and output integration
    • Murray P.J. The JAK-STAT signaling pathway: input and output integration. J. Immunol. 2007, 178:2623-2629.
    • (2007) J. Immunol. , vol.178 , pp. 2623-2629
    • Murray, P.J.1
  • 55
    • 27944442806 scopus 로고    scopus 로고
    • Min/+ mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
    • Min/+ mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int. J. Cancer 2006, 118:25-34.
    • (2006) Int. J. Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1
  • 56
    • 33751361302 scopus 로고    scopus 로고
    • Bacteria, inflammation, and colon cancer
    • Yang L., Pei Z. Bacteria, inflammation, and colon cancer. World J. Gastroenterol. 2006, 12:6741-6746.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 6741-6746
    • Yang, L.1    Pei, Z.2
  • 57
    • 69249232549 scopus 로고    scopus 로고
    • Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells
    • Garrett W.S., et al. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell 2009, 16:208-219.
    • (2009) Cancer Cell , vol.16 , pp. 208-219
    • Garrett, W.S.1
  • 58
    • 70349101236 scopus 로고    scopus 로고
    • -/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships
    • -/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships. Cytokine 2009, 48:144-147.
    • (2009) Cytokine , vol.48 , pp. 144-147
    • Garrett, W.S.1    Glimcher, L.H.2
  • 59
    • 0030614675 scopus 로고    scopus 로고
    • Min mouse: independence from the microbial and natural killer (beige locus) status
    • Min mouse: independence from the microbial and natural killer (beige locus) status. Cancer Res. 1997, 57:812-814.
    • (1997) Cancer Res. , vol.57 , pp. 812-814
    • Dove, W.F.1
  • 60
    • 84906553545 scopus 로고    scopus 로고
    • -/- mice
    • -/- mice. Gastroenterology 2014, 147:667-679.
    • (2014) Gastroenterology , vol.147 , pp. 667-679
    • Im, E.1
  • 61
    • 84867192879 scopus 로고    scopus 로고
    • Intestinal inflammation targets cancer-inducing activity of the microbiota
    • Arthur J.C., et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012, 338:120-123.
    • (2012) Science , vol.338 , pp. 120-123
    • Arthur, J.C.1
  • 62
    • 77954730486 scopus 로고    scopus 로고
    • Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells
    • Cuevas-Ramos G., et al. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11537-11542.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11537-11542
    • Cuevas-Ramos, G.1
  • 63
    • 33747137269 scopus 로고    scopus 로고
    • Escherichia coli induces DNA double-strand breaks in eukaryotic cells
    • Nougayrede J.P., et al. Escherichia coli induces DNA double-strand breaks in eukaryotic cells. Science 2006, 313:848-851.
    • (2006) Science , vol.313 , pp. 848-851
    • Nougayrede, J.P.1
  • 64
    • 34249886868 scopus 로고    scopus 로고
    • CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
    • Barnich N., et al. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J. Clin. Invest. 2007, 117:1566-1574.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1566-1574
    • Barnich, N.1
  • 65
    • 59049106578 scopus 로고    scopus 로고
    • Crypt stem cells as the cells-of-origin of intestinal cancer
    • Barker N., et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 2009, 457:608-611.
    • (2009) Nature , vol.457 , pp. 608-611
    • Barker, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.