Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia

Journal of Lipid Research

Volumn 55, Issue 11, 2014, Pages 2242-2253

  O'Hare, Elizabeth A ^a   Wang, Xiaochun ^a   Montasser, May E ^a   Chang, Yen Pei C ^a   Mitchell, Braxton D ^a   Zaghloul, Norann A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Low density lipoprotein; Low density lipoprotein cholesterol; Low density lipoprotein receptor

Indexed keywords

ATORVASTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; HEPTANOIC ACID DERIVATIVE; MORPHOLINO OLIGONUCLEOTIDE; PYRROLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENETIC MODEL; HEPATOMEGALY; HYPERCHOLESTEROLEMIA; LARVAL STAGE; LIPID OXIDATION; LIPID STORAGE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; TAIL VEIN; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; BLOOD VESSEL; COMPLICATION; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; LIVER; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; VEIN;

ANIMALS; BASE SEQUENCE; BLOOD VESSELS; CHOLESTEROL, LDL; DISEASE MODELS, ANIMAL; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEPATOMEGALY; HEPTANOIC ACIDS; HYPERCHOLESTEROLEMIA; LIVER; MOLECULAR SEQUENCE DATA; MORPHOLINOS; OXIDATION-REDUCTION; PYRROLES; RECEPTORS, LDL; VEINS; ZEBRAFISH;

EID: 84939515490     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M046540     Document Type: Article

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