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Volumn 47, Issue 7, 2006, Pages 1399-1405

Binding characteristics of a panel of monoclonal antibodies against the ligand binding domain of the human LDLr

Author keywords

Knockout mice; Low density lipoprotein receptor; Structure function analysis

Indexed keywords

EPITOPE; LOW DENSITY LIPOPROTEIN RECEPTOR; MONOCLONAL ANTIBODY;

EID: 33746048475     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M600130-JLR200     Document Type: Article
Times cited : (15)

References (34)
  • 1
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown, M. S., and J. L. Goldstein. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science. 232: 34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 2
    • 22244478077 scopus 로고    scopus 로고
    • Structure and physiologic function of the low-density lipoprotein receptor
    • Jeon, H., and S. C. Blacklow. 2005. Structure and physiologic function of the low-density lipoprotein receptor. Annu. Rev. Biochem. 74: 535-562.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 535-562
    • Jeon, H.1    Blacklow, S.C.2
  • 3
    • 0035013711 scopus 로고    scopus 로고
    • Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair
    • Jeon, H., W. Y. Meng, J. Takagi, M. J. Eck, T. A. Springer, and S. C. Blacklow. 2001. Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat. Struct. Biol. 8: 499-504.
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 499-504
    • Jeon, H.1    Meng, W.Y.2    Takagi, J.3    Eck, M.J.4    Springer, T.A.5    Blacklow, S.C.6
  • 5
    • 0029780956 scopus 로고    scopus 로고
    • Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor
    • Blacklow, S. C., and P. S. Kim. 1996. Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor. Nat. Struct. Biol. 3: 758-762.
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 758-762
    • Blacklow, S.C.1    Kim, P.S.2
  • 6
    • 0028822131 scopus 로고
    • Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain
    • Bieri, S., J. T. Djordjevic, N. L. Daly, R. Smith, and P. A. Kroon. 1995. Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain. Biochemistry. 34: 13059-13065.
    • (1995) Biochemistry , vol.34 , pp. 13059-13065
    • Bieri, S.1    Djordjevic, J.T.2    Daly, N.L.3    Smith, R.4    Kroon, P.A.5
  • 7
    • 0030759357 scopus 로고    scopus 로고
    • Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
    • Fass, D., S. C. Blacklow, P. S. Kim, and J. M. Berger. 1997. Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module. Nature. 388: 691-693.
    • (1997) Nature , vol.388 , pp. 691-693
    • Fass, D.1    Blacklow, S.C.2    Kim, P.S.3    Berger, J.M.4
  • 8
    • 0033852848 scopus 로고    scopus 로고
    • NMR structure of a concatemer of the first and second ligand-binding modules of the human lowdensity lipoprotein receptor
    • Kurniawan, N. D., A. R. Atkins, S. Bieri, C. J. Brown, I. M. Brereton, P. A. Kroon, and R. Smith. 2000. NMR structure of a concatemer of the first and second ligand-binding modules of the human lowdensity lipoprotein receptor. Protein Sci. 9: 1282-1293.
    • (2000) Protein Sci. , vol.9 , pp. 1282-1293
    • Kurniawan, N.D.1    Atkins, A.R.2    Bieri, S.3    Brown, C.J.4    Brereton, I.M.5    Kroon, P.A.6    Smith, R.7
  • 9
    • 0037147191 scopus 로고    scopus 로고
    • Coordinated nonvectorial folding in a newly synthesized multidomain protein
    • Jansens, A., E. van Duijn, and I. Braakman. 2002. Coordinated nonvectorial folding in a newly synthesized multidomain protein. Science. 298: 2401-2403.
    • (2002) Science , vol.298 , pp. 2401-2403
    • Jansens, A.1    Van Duijn, E.2    Braakman, I.3
  • 10
    • 0023750089 scopus 로고
    • Mutational analysis of the ligand binding domain of the low density lipoprotein receptor
    • Esser, V., L. E. Limbird, M. S. Brown, J. L. Goldstein, and D. W. Russell. 1988. Mutational analysis of the ligand binding domain of the low density lipoprotein receptor. J. Biol. Chem. 263: 13282-13290.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13282-13290
    • Esser, V.1    Limbird, L.E.2    Brown, M.S.3    Goldstein, J.L.4    Russell, D.W.5
  • 11
    • 0024806811 scopus 로고
    • Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins
    • Russell, D. W., M. S. Brown, and J. L. Goldstein. 1989. Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins. J. Biol. Chem. 264: 21682-21688.
    • (1989) J. Biol. Chem. , vol.264 , pp. 21682-21688
    • Russell, D.W.1    Brown, M.S.2    Goldstein, J.L.3
  • 12
    • 0942268917 scopus 로고    scopus 로고
    • A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands
    • Fisher, C., D. Abdul-Aziz, and S. C. Blacklow. 2004. A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands. Biochemistry. 43: 1037-1044.
    • (2004) Biochemistry , vol.43 , pp. 1037-1044
    • Fisher, C.1    Abdul-Aziz, D.2    Blacklow, S.C.3
  • 13
    • 0034730626 scopus 로고    scopus 로고
    • Vesicle-reconstituted low density lipoprotein receptor. Visualization by cryoelectron microscopy
    • Jeon, H., and G. G. Shipley. 2000. Vesicle-reconstituted low density lipoprotein receptor. Visualization by cryoelectron microscopy. J. Biol. Chem. 275: 30458-30464.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30458-30464
    • Jeon, H.1    Shipley, G.G.2
  • 14
    • 0037147180 scopus 로고    scopus 로고
    • LDL receptor's b-propeller displaces LDL
    • Innerarity, T. L. 2002. LDL receptor's b-propeller displaces LDL. Science. 298: 2337-2339.
    • (2002) Science , vol.298 , pp. 2337-2339
    • Innerarity, T.L.1
  • 15
    • 0346850975 scopus 로고    scopus 로고
    • The low density lipoprotein receptor: Ligands, debates and lore
    • Rudenko, G., and J. Deisenhofer. 2003. The low density lipoprotein receptor: ligands, debates and lore. Curr. Opin. Struct. Biol. 13: 683-689.
    • (2003) Curr. Opin. Struct. Biol. , vol.13 , pp. 683-689
    • Rudenko, G.1    Deisenhofer, J.2
  • 16
    • 6344253104 scopus 로고    scopus 로고
    • Cooperation between fixed and low pH-inducible interfaces controls lipoprotein release by the LDL receptor
    • Beglova, N., H. Jeon, C. Fisher, and S. C. Blacklow. 2004. Cooperation between fixed and low pH-inducible interfaces controls lipoprotein release by the LDL receptor. Mol. Cell. 16: 281-292.
    • (2004) Mol. Cell. , vol.16 , pp. 281-292
    • Beglova, N.1    Jeon, H.2    Fisher, C.3    Blacklow, S.C.4
  • 17
    • 0023392945 scopus 로고
    • High efficiency transformation of mammalian cells by plasmid DNA
    • Chen, C., and H. Okayama. 1987. High efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7: 2745-2752.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2745-2752
    • Chen, C.1    Okayama, H.2
  • 18
    • 0019888656 scopus 로고
    • Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia
    • Beisiegel, U., W. J. Schneider, J. L. Goldstein, R. G. W. Anderson, and M. S. Brown. 1981. Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia. J. Biol. Chem. 256: 11923-11931.
    • (1981) J. Biol. Chem. , vol.256 , pp. 11923-11931
    • Beisiegel, U.1    Schneider, W.J.2    Goldstein, J.L.3    Anderson, R.G.W.4    Brown, M.S.5
  • 19
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S., M. S. Brown, J. L. Goldstein, R. D. Gerard, R. E. Hammer, and J. Herz. 1993. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92: 883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 20
    • 0013423664 scopus 로고
    • Immunological methods for studying and quantifying lipoproteins and apolipoproteins
    • C. Converse and E. Skinner, editors. Oxford University Press, Oxford
    • Milne, R. W., P. K. Weech, and Y. L. Marcel. 1992. Immunological methods for studying and quantifying lipoproteins and apolipoproteins. In Lipoprotein Analysis: A Practical Approach. C. Converse and E. Skinner, editors. Oxford University Press, Oxford. 61-84.
    • (1992) Lipoprotein Analysis: A Practical Approach , pp. 61-84
    • Milne, R.W.1    Weech, P.K.2    Marcel, Y.L.3
  • 21
    • 0020567978 scopus 로고
    • Characterization of monoclonal antibodies against human low density lipoprotein
    • Milne, R. W., R. Theolis, R. B. Verdery, and Y. L. Marcel. 1983. Characterization of monoclonal antibodies against human low density lipoprotein. Arteriosclerosis. 3: 23-30.
    • (1983) Arteriosclerosis , vol.3 , pp. 23-30
    • Milne, R.W.1    Theolis, R.2    Verdery, R.B.3    Marcel, Y.L.4
  • 22
    • 0020414563 scopus 로고
    • Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia
    • Beisiegel, U., W. J. Schneider, M. S. Brown, and J. L. Goldstein. 1982. Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia. J. Biol. Chem. 257: 13150-13156.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13150-13156
    • Beisiegel, U.1    Schneider, W.J.2    Brown, M.S.3    Goldstein, J.L.4
  • 23
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • Havel, R. J., H. A. Eder, and J. H. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34: 1345-1353.
    • (1955) J. Clin. Invest. , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 24
    • 0015518106 scopus 로고
    • The metabolism of very low density lipoprotein proteins
    • Bilheimer, D. W., S. Eisenberg, and R. I. Levy. 1972. The metabolism of very low density lipoprotein proteins. Biochim. Biophys. Acta. 260: 212-221.
    • (1972) Biochim. Biophys. Acta , vol.260 , pp. 212-221
    • Bilheimer, D.W.1    Eisenberg, S.2    Levy, R.I.3
  • 27
    • 0025868703 scopus 로고
    • The epitopes of apolipoprotein A-I define distinct structural domains including a mobile middle region
    • Marcel, Y. L., P. R. Provost, H. Koa, E. Raffai, N. V. Dac, J. C. Fruchart, and E. Rassart. 1991. The epitopes of apolipoprotein A-I define distinct structural domains including a mobile middle region. J. Biol. Chem. 266: 3644-3653.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3644-3653
    • Marcel, Y.L.1    Provost, P.R.2    Koa, H.3    Raffai, E.4    Dac, N.V.5    Fruchart, J.C.6    Rassart, E.7
  • 28
    • 0020623947 scopus 로고
    • A computer program for predicting antigenic determinants
    • Hopp, T. P., and K. R. Woods. 1983. A computer program for predicting antigenic determinants. Mol. Immunol. 20: 483-489.
    • (1983) Mol. Immunol. , vol.20 , pp. 483-489
    • Hopp, T.P.1    Woods, K.R.2
  • 29
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157: 105-132.
    • (1982) J. Mol. Biol. , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 30
    • 0030058974 scopus 로고    scopus 로고
    • Structure-function relationships of human cholesteryl ester transfer protein: Analysis using monoclonal antibodies
    • Roy, P., R. Mac, T. Kenzie, X. C. Hirama, P. Jiang, P. Kussie, A. Tall, E. Rassart, and R. Milne. 1996. Structure-function relationships of human cholesteryl ester transfer protein: analysis using monoclonal antibodies. J. Lipid Res. 37: 22-34.
    • (1996) J. Lipid Res. , vol.37 , pp. 22-34
    • Roy, P.1    Mac, R.2    Kenzie, T.3    Hirama, X.C.4    Jiang, P.5    Kussie, P.6    Tall, A.7    Rassart, E.8    Milne, R.9
  • 31
    • 0032748032 scopus 로고    scopus 로고
    • Immunochemical evidence that cholesteryl ester transfer protein and bactericidal/permeability-increasing protein share a similar tertiary structure
    • Guyard-Dangremont, V., V. Tenekjian, V. Chauhan, S. Walter, P. Roy, E. Rassart, and R. Milne. 1999. Immunochemical evidence that cholesteryl ester transfer protein and bactericidal/permeability-increasing protein share a similar tertiary structure. Protein Sci. 8: 2392-2398.
    • (1999) Protein Sci. , vol.8 , pp. 2392-2398
    • Guyard-Dangremont, V.1    Tenekjian, V.2    Chauhan, V.3    Walter, S.4    Roy, P.5    Rassart, E.6    Milne, R.7
  • 32
    • 0038241707 scopus 로고    scopus 로고
    • Genomic evidence for the absence of a functional cholesteryl ester transfer protein gene in mice and rats
    • Hogarth, C. A., A. Roy, and D. I. Ebert. 2003. Genomic evidence for the absence of a functional cholesteryl ester transfer protein gene in mice and rats. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 135: 219-229.
    • (2003) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.135 , pp. 219-229
    • Hogarth, C.A.1    Roy, A.2    Ebert, D.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.