In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

Journal of Clinical Investigation

Volumn 121, Issue 12, 2011, Pages 4861-4869

  Fang, Longhou ^a   Green, Simone R ^a   Baek, Ji Sun ^a   Lee, Sang Hak ^a   Ellett, Felix ^b,c   Deer, Elena ^a   Lieschke, Graham J ^b,c   Witztum, Joseph L ^a   Tsimikas, Sotirios ^a   Miller, Yury I ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IK 17 ANTIBODY; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; MONOCLONAL ANTIBODY; RED FLUORESCENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD VESSEL WALL; CHOLESTEROL DIET; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; FEEDING; HEAT SHOCK; HYPERCHOLESTEROLEMIA; IN VIVO STUDY; LARVA; LIPID OXIDATION; LIPID STORAGE; MACROPHAGE; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES, MONOCLONAL; ANTICHOLESTEREMIC AGENTS; BLOOD VESSELS; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; EPITOPES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; HYDRAZINES; HYPERCHOLESTEROLEMIA; IMMUNOGLOBULIN FAB FRAGMENTS; LIPOPROTEINS, LDL; MACROPHAGES; MALONDIALDEHYDE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; OXIDATION-REDUCTION; PORPHOBILINOGEN; PROBUCOL; RECOMBINANT FUSION PROTEINS; SINGLE-CHAIN ANTIBODIES; TEMPERATURE; VEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84055199892     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI57755     Document Type: Article

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