Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

Epigenetics

Volumn 10, Issue 5, 2015, Pages 397-407

  Ruiz, Maria Armila ^a,b   Rivers, Angela ^a,b   Ibanez, Vinzon ^a,b   Vaitkus, Kestis ^a,b   Mahmud, Nadim ^b   Desimone, Joseph ^a,b   Lavelle, Donald ^a,b  

^a JESSE BROWN VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Decitabine; DNA methylation; Erythropoiesis; Globin gene switching; Hydroxymethylcytosine; Tranylcypromine; Vitamin C; globin gene

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; ASCORBIC ACID; DECITABINE; DNA METHYLTRANSFERASE; HEMOGLOBIN GAMMA CHAIN; HYDROXYUREA; TRANYLCYPROMINE; 5 METHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; ANTINEOPLASTIC AGENT; AZACITIDINE; CYTOSINE; DIOXYGENASE; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; TET3 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BABOON; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA METHYLATION; ERYTHROID CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTONE DEMETHYLATION; NONHUMAN; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TET3 GENE; ANALOGS AND DERIVATIVES; ANIMAL; BONE MARROW CELL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; HUMAN; LIVER; METABOLISM; NEWBORN; PAPIO ANUBIS;

5-METHYLCYTOSINE; ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; ASCORBIC ACID; AZACITIDINE; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOSINE; DIOXYGENASES; DNA METHYLATION; ERYTHROID CELLS; GAMMA-GLOBINS; HISTONE DEMETHYLASES; HUMANS; HYDROXYUREA; LIVER; PAPIO ANUBIS; PROMOTER REGIONS, GENETIC; TRANYLCYPROMINE;

EID: 84939475064     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1039220     Document Type: Article

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