-
1
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M., Koh K.P., Shen Y., et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324(5929):930-935.
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
2
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S., D'Alessio A.C., Taranova O.V., Hong K., Sowers L.C., Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature. 2010;466(7310):1129-1133.
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
3
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G., Branco M.R., Seisenberger S., et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature. 2011;473(7347):398-402.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
-
4
-
-
67650924270
-
Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
-
Tefferi A., Lim K.H., Abdel-Wahab O., et al. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. Leukemia. 2009;23(7):1343-1345.
-
(2009)
Leukemia
, vol.23
, Issue.7
, pp. 1343-1345
-
-
Tefferi, A.1
Lim, K.H.2
Abdel-Wahab, O.3
-
5
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer S.M., Kuiper R.P., Berends M., et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet. 2009;41(7):838-842.
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
-
6
-
-
67650588639
-
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
-
Jankowska A.M., Szpurka H., Tiu R.V., et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood. 2009;113(25):6403-6410.
-
(2009)
Blood
, vol.113
, Issue.25
, pp. 6403-6410
-
-
Jankowska, A.M.1
Szpurka, H.2
Tiu, R.V.3
-
7
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau F., Dupont S., Della Valle V., et al. Mutation in TET2 in myeloid cancers. N Engl J Med. 2009;360(22):2289-2301.
-
(2009)
N Engl J Med
, vol.360
, Issue.22
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della Valle, V.3
-
8
-
-
67651065502
-
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
-
Abdel-Wahab O., Mullally A., Hedvat C., et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 2009;114(1):144-147.
-
(2009)
Blood
, vol.114
, Issue.1
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
-
9
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa M.E., Abdel-Wahab O., Lu C., et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010;18(6):553-567.
-
(2010)
Cancer Cell
, vol.18
, Issue.6
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
-
10
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko M., Huang Y., Jankowska A.M., et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 2010;468(7325):839-843.
-
(2010)
Nature
, vol.468
, Issue.7325
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
-
11
-
-
34547936938
-
The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera
-
Dupont S., Masse A., James C., et al. The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera. Blood. 2007;110(3):1013- 1021.
-
(2007)
Blood
, vol.110
, Issue.3
, pp. 1013-1021
-
-
Dupont, S.1
Masse, A.2
James, C.3
-
12
-
-
77955375894
-
Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats
-
Marie-Desvergne C., Maitre A., Bouchard M., Ravanat J.L., Viau C. Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats. Chem Res Toxicol. 2010;23(7):1207-1214.
-
(2010)
Chem Res Toxicol
, vol.23
, Issue.7
, pp. 1207-1214
-
-
Marie-Desvergne, C.1
Maitre, A.2
Bouchard, M.3
Ravanat, J.L.4
Viau, C.5
-
13
-
-
12244279345
-
Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry
-
DOI 10.1021/ac0489420
-
Song L., James S.R., Kazim L., Karpf A.R. Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Anal Chem. 2005;77(2):504-510. (Pubitemid 40116829)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.2
, pp. 504-510
-
-
Song, L.1
James, S.R.2
Kazim, L.3
Karpf, A.R.4
-
14
-
-
77950537579
-
MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9
-
Gilles L., Bluteau D., Boukour S., et al. MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9. Blood. 2009;114(19):4221-4232.
-
(2009)
Blood
, vol.114
, Issue.19
, pp. 4221-4232
-
-
Gilles, L.1
Bluteau, D.2
Boukour, S.3
-
15
-
-
33846007215
-
Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis
-
DOI 10.1182/blood-2006-03-007146
-
Delhommeau F., Dupont S., Tonetti C., et al. Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis. Blood. 2007;109(1):71-77. (Pubitemid 46053046)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 71-77
-
-
Delhommeau, F.1
Dupont, S.2
Tonetti, C.3
Masse, A.4
Godin, I.5
Le, C.J.-P.6
Debili, N.7
Saulnier, P.8
Casadevall, N.9
Vainchenker, W.10
Giraudier, S.11
-
16
-
-
73149094518
-
TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia
-
Kosmider O., Gelsi-Boyer V., Ciudad M., et al. TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia. Haematologica. 2009;94(12):1676-1681.
-
(2009)
Haematologica
, vol.94
, Issue.12
, pp. 1676-1681
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Ciudad, M.3
-
17
-
-
77956237515
-
Nextgeneration sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1
-
Kohlmann A., Grossmann V., Klein H.U., et al. Nextgeneration sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1. J Clin Oncol. 2010;28(24):3858-3865.
-
(2010)
J Clin Oncol
, vol.28
, Issue.24
, pp. 3858-3865
-
-
Kohlmann, A.1
Grossmann, V.2
Klein, H.U.3
-
18
-
-
77950388949
-
Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms
-
Schaub F.X., Looser R., Li S., et al. Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms. Blood. 2010;115(10):2003-2007.
-
(2010)
Blood
, vol.115
, Issue.10
, pp. 2003-2007
-
-
Schaub, F.X.1
Looser, R.2
Li, S.3
-
19
-
-
77949732119
-
Mutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis
-
Flach J., Dicker F., Schnittger S., Kohlmann A., Haferlach T., Haferlach C. Mutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis. Haematologica. 2010;95(3):518-519.
-
(2010)
Haematologica
, vol.95
, Issue.3
, pp. 518-519
-
-
Flach, J.1
Dicker, F.2
Schnittger, S.3
Kohlmann, A.4
Haferlach, T.5
Haferlach, C.6
-
20
-
-
67649872341
-
TET2 mutations in myelodysplasia and myeloid malignancies
-
Mullighan C.G. TET2 mutations in myelodysplasia and myeloid malignancies. Nat Genet. 2009;41(7):766-767.
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 766-767
-
-
Mullighan, C.G.1
-
21
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge J.J., Snow J.W., Kim J., Orkin S.H. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell. 2009;5(4):442-449.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.4
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
22
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Bröske A.M., Vockentanz L., Kharazi S., et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet. 2009;41(11):1207-1215.
-
(2009)
Nat Genet
, vol.41
, Issue.11
, pp. 1207-1215
-
-
Bröske, A.M.1
Vockentanz, L.2
Kharazi, S.3
-
23
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley T.J., Ding L., Walter M.J., et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363(25):2424-2433.
-
(2010)
N Engl J Med
, vol.363
, Issue.25
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
|