메뉴 건너뛰기




Volumn 137, Issue , 2015, Pages 125-132

Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin

Author keywords

Antimicrobial; Flavonoid; Hesperetin; Hesperidin; Toxin

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; ANTIPARASITIC AGENT; FOOD ADDITIVE; HEAVY METAL; HESPERETIN; HESPERIDIN; INSECTICIDE; NICOTINE; ANTIINFECTIVE AGENT; PROTECTIVE AGENT;

EID: 84939451448     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.07.014     Document Type: Review
Times cited : (174)

References (64)
  • 1
    • 79952278945 scopus 로고    scopus 로고
    • Hesperidin alleviates doxorubicin-induced cardiotoxicity in rats
    • I.T. Abdel-Raheem, and A.A. Abdel-Ghany Hesperidin alleviates doxorubicin-induced cardiotoxicity in rats J. Egypt. Natl. Canc. Inst. 21 2009 175 184
    • (2009) J. Egypt. Natl. Canc. Inst. , vol.21 , pp. 175-184
    • Abdel-Raheem, I.T.1    Abdel-Ghany, A.A.2
  • 2
    • 84891274785 scopus 로고    scopus 로고
    • The protective effect of hesperidin on methotrexate-induced intestinal epithelial damage in rats: An experimental study
    • C. Acipayam, I. Bayram, K. Daglioglu, F. Doran, and et al. The protective effect of hesperidin on methotrexate-induced intestinal epithelial damage in rats: an experimental study Med. Princ. Pract. 23 2014 45 52
    • (2014) Med. Princ. Pract. , vol.23 , pp. 45-52
    • Acipayam, C.1    Bayram, I.2    Daglioglu, K.3    Doran, F.4
  • 3
    • 84905656416 scopus 로고    scopus 로고
    • In vitro and in vivo effects of hesperidin treatment on adult worms of Schistosoma mansoni
    • G. Allam, and A.S. Abuelsaad In vitro and in vivo effects of hesperidin treatment on adult worms of Schistosoma mansoni J. Helminthol. 88 2014 362 370
    • (2014) J. Helminthol. , vol.88 , pp. 362-370
    • Allam, G.1    Abuelsaad, A.S.2
  • 4
    • 84867662678 scopus 로고    scopus 로고
    • Renal protective effect of hesperidin on gentamicin-induced acute nephrotoxicity in male Wistar albino rats
    • R. Anandan, and P. Subramanian Renal protective effect of hesperidin on gentamicin-induced acute nephrotoxicity in male Wistar albino rats Redox Rep. 17 2012 219 226
    • (2012) Redox Rep. , vol.17 , pp. 219-226
    • Anandan, R.1    Subramanian, P.2
  • 5
    • 0033774579 scopus 로고    scopus 로고
    • In vitro inhibitory effect of some flavonoids on rotavirus infectivity
    • E.A. Bae, M.J. Han, M. Lee, and D.H. Kim In vitro inhibitory effect of some flavonoids on rotavirus infectivity Biol. Pharm. Bull. 23 2000 1122 1124
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 1122-1124
    • Bae, E.A.1    Han, M.J.2    Lee, M.3    Kim, D.H.4
  • 6
    • 84871301162 scopus 로고    scopus 로고
    • Protective effects of fermented Citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibrobolasts
    • J.T. Bae, H.J. Ko, G.B. Kim, H.B. Pyo, and et al. Protective effects of fermented Citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibrobolasts Phytother. Res. 26 2012 1851 1856
    • (2012) Phytother. Res. , vol.26 , pp. 1851-1856
    • Bae, J.T.1    Ko, H.J.2    Kim, G.B.3    Pyo, H.B.4
  • 7
    • 34047261247 scopus 로고    scopus 로고
    • Protective effect of hesperidin on nicotine induced toxicity in rats
    • A. Balakrishnan, and V.P. Menon Protective effect of hesperidin on nicotine induced toxicity in rats Indian J. Exp. Biol. 45 2007 194 202
    • (2007) Indian J. Exp. Biol. , vol.45 , pp. 194-202
    • Balakrishnan, A.1    Menon, V.P.2
  • 8
    • 84879310903 scopus 로고    scopus 로고
    • Cadmium toxicity and treatment
    • R.A. Bernhoft Cadmium toxicity and treatment ScientificWorldJournal 2013 2013 394652
    • (2013) ScientificWorldJournal , vol.2013 , pp. 394652
    • Bernhoft, R.A.1
  • 9
    • 84881549275 scopus 로고    scopus 로고
    • In vitro inhibition of canine distemper virus by flavonoids and phenolic acids: Implications of structural differences for antiviral design
    • O.V. Carvalho, C.V. Botelho, C.G. Ferreira, H.C. Ferreira, and et al. In vitro inhibition of canine distemper virus by flavonoids and phenolic acids: implications of structural differences for antiviral design Res. Vet. Sci. 95 2013 717 724
    • (2013) Res. Vet. Sci. , vol.95 , pp. 717-724
    • Carvalho, O.V.1    Botelho, C.V.2    Ferreira, C.G.3    Ferreira, H.C.4
  • 10
    • 84874547456 scopus 로고    scopus 로고
    • Pummelo protects doxorubicin-induced cardiac cell death by reducing oxidative stress, modifying glutathione transferase expression, and preventing cellular senescence
    • L. Chularojmontri, O. Gerdprasert, and S.K. Wattanapitayakul Pummelo protects doxorubicin-induced cardiac cell death by reducing oxidative stress, modifying glutathione transferase expression, and preventing cellular senescence Evid. Based Complement. Alternat. Med. 2013 2013 254835
    • (2013) Evid. Based Complement. Alternat. Med. , vol.2013 , pp. 254835
    • Chularojmontri, L.1    Gerdprasert, O.2    Wattanapitayakul, S.K.3
  • 12
    • 6344291042 scopus 로고    scopus 로고
    • Antimicrobial activity of grapefruit seed and pulp ethanolic extract
    • Z. Cvetnic, and S. Vladimir-Knezevic Antimicrobial activity of grapefruit seed and pulp ethanolic extract Acta Pharma. 54 2004 243 250
    • (2004) Acta Pharma. , vol.54 , pp. 243-250
    • Cvetnic, Z.1    Vladimir-Knezevic, S.2
  • 13
    • 84859161959 scopus 로고    scopus 로고
    • Polyphenols as antimicrobial agents
    • M. Daglia Polyphenols as antimicrobial agents Curr. Opin. Biotechnol. 23 2012 174 181
    • (2012) Curr. Opin. Biotechnol. , vol.23 , pp. 174-181
    • Daglia, M.1
  • 14
    • 4544289287 scopus 로고    scopus 로고
    • Protective activity of hesperidin and lipoic acid against sodium arsenite acute toxicity in mice
    • R.N.P. das Neves, F. Carvalho, M. Carvalho, E. Fernandes, and et al. Protective activity of hesperidin and lipoic acid against sodium arsenite acute toxicity in mice Toxicol. Pathol. 32 2004 527 535
    • (2004) Toxicol. Pathol. , vol.32 , pp. 527-535
    • Das Neves, R.N.P.1    Carvalho, F.2    Carvalho, M.3    Fernandes, E.4
  • 16
    • 84870585864 scopus 로고    scopus 로고
    • The inhibitory effect of polyphenols on human gut microbiota
    • A. Duda-Chodak The inhibitory effect of polyphenols on human gut microbiota J. Physiol. Pharmacol. 63 2012 497 503
    • (2012) J. Physiol. Pharmacol. , vol.63 , pp. 497-503
    • Duda-Chodak, A.1
  • 17
    • 84903371826 scopus 로고    scopus 로고
    • Synthesis and antibacterial evaluation of some novel hesperidin semisynthetic derivatives
    • N. Duganath, C. Sridhar, and K.N. Jayaveera Synthesis and antibacterial evaluation of some novel hesperidin semisynthetic derivatives Der Pharmacia Lettre 6 2014 87 94
    • (2014) Der Pharmacia Lettre , vol.6 , pp. 87-94
    • Duganath, N.1    Sridhar, C.2    Jayaveera, K.N.3
  • 18
    • 84901372782 scopus 로고    scopus 로고
    • Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats
    • S.M. Elshazly, and A.A. Mahmoud Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats Naunyn Schmiedeberg's Arch. Pharmacol. 387 2014 559 567
    • (2014) Naunyn Schmiedeberg's Arch. Pharmacol. , vol.387 , pp. 559-567
    • Elshazly, S.M.1    Mahmoud, A.A.2
  • 19
    • 61849129297 scopus 로고    scopus 로고
    • Heavy metal induced oxidative stress & its possible reversal by chelation therapy
    • S.J. Flora, M. Mittal, and A. Mehta Heavy metal induced oxidative stress & its possible reversal by chelation therapy Indian J. Med. Res. 128 2008 501 523
    • (2008) Indian J. Med. Res. , vol.128 , pp. 501-523
    • Flora, S.J.1    Mittal, M.2    Mehta, A.3
  • 20
    • 18244370245 scopus 로고    scopus 로고
    • Biological activity assessment of a novel contraceptive antimicrobial agent
    • A. Garg, R.A. Anderson, L.J. Zaneveld, and S. Garg Biological activity assessment of a novel contraceptive antimicrobial agent J. Androl. 26 2005 414 421
    • (2005) J. Androl. , vol.26 , pp. 414-421
    • Garg, A.1    Anderson, R.A.2    Zaneveld, L.J.3    Garg, S.4
  • 21
    • 0035667114 scopus 로고    scopus 로고
    • Chemistry and pharmacology of the citrus bioflavonoid hesperidin
    • A. Garg, S. Garg, L.J. Zaneveld, and A.K. Singla Chemistry and pharmacology of the citrus bioflavonoid hesperidin Phytother. Res. 15 2001 655 669
    • (2001) Phytother. Res. , vol.15 , pp. 655-669
    • Garg, A.1    Garg, S.2    Zaneveld, L.J.3    Singla, A.K.4
  • 22
    • 0034736046 scopus 로고    scopus 로고
    • Advances in flavonoid research since 1992
    • J.B. Harborne, and C.A. Williams Advances in flavonoid research since 1992 Phytochemistry 55 2000 481 504
    • (2000) Phytochemistry , vol.55 , pp. 481-504
    • Harborne, J.B.1    Williams, C.A.2
  • 23
    • 0036849077 scopus 로고    scopus 로고
    • The biochemistry and medical significance of the flavonoids
    • B.H. Havsteen The biochemistry and medical significance of the flavonoids Pharmacol. Ther. 96 2002 67 202
    • (2002) Pharmacol. Ther. , vol.96 , pp. 67-202
    • Havsteen, B.H.1
  • 25
    • 66749145658 scopus 로고    scopus 로고
    • Radioprotective effects of hesperidin against genotoxicity induced by gamma-irradiation in human lymphocytes
    • S.J. Hosseinimehr, A. Mahmoudzadeh, A. Ahmadi, S. Mohamadifar, and et al. Radioprotective effects of hesperidin against genotoxicity induced by gamma-irradiation in human lymphocytes Mutagenesis 24 2009 233 235
    • (2009) Mutagenesis , vol.24 , pp. 233-235
    • Hosseinimehr, S.J.1    Mahmoudzadeh, A.2    Ahmadi, A.3    Mohamadifar, S.4
  • 26
    • 33646390956 scopus 로고    scopus 로고
    • Radioprotective effects of hesperidin against gamma irradiation in mouse bone marrow cells
    • S.J. Hosseinimehr, and A. Nemati Radioprotective effects of hesperidin against gamma irradiation in mouse bone marrow cells Br. J. Radiol. 79 2006 415 418
    • (2006) Br. J. Radiol. , vol.79 , pp. 415-418
    • Hosseinimehr, S.J.1    Nemati, A.2
  • 27
    • 79961126298 scopus 로고    scopus 로고
    • Hesperidin promotes cyclobutane pyrimidine dimer repair in UVB-exposed mice epidermis
    • S. Jin, B. Zhou, and D. Luo Hesperidin promotes cyclobutane pyrimidine dimer repair in UVB-exposed mice epidermis Ir. J. Med. Sci. 180 2011 709 714
    • (2011) Ir. J. Med. Sci. , vol.180 , pp. 709-714
    • Jin, S.1    Zhou, B.2    Luo, D.3
  • 28
    • 67349183982 scopus 로고    scopus 로고
    • Investigation of the radioprotective efficacy of hesperidin against gamma-radiation induced cellular damage in cultured human peripheral blood lymphocytes
    • K.B. Kalpana, N. Devipriya, M. Srinivasan, and V.P. Menon Investigation of the radioprotective efficacy of hesperidin against gamma-radiation induced cellular damage in cultured human peripheral blood lymphocytes Mutat. Res. 676 2009 54 61
    • (2009) Mutat. Res. , vol.676 , pp. 54-61
    • Kalpana, K.B.1    Devipriya, N.2    Srinivasan, M.3    Menon, V.P.4
  • 29
    • 79953769096 scopus 로고    scopus 로고
    • Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice
    • K.B. Kalpana, N. Devipriya, M. Srinivasan, P. Vishwanathan, and et al. Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice Eur. J. Pharmacol. 658 2011 206 212
    • (2011) Eur. J. Pharmacol. , vol.658 , pp. 206-212
    • Kalpana, K.B.1    Devipriya, N.2    Srinivasan, M.3    Vishwanathan, P.4
  • 30
    • 16644397617 scopus 로고    scopus 로고
    • A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice
    • K. Kawaguchi, S. Kikuchi, R. Hasunuma, H. Maruyama, and et al. A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice Biol. Pharm. Bull. 27 2004 679 683
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 679-683
    • Kawaguchi, K.1    Kikuchi, S.2    Hasunuma, R.3    Maruyama, H.4
  • 31
    • 0002238959 scopus 로고
    • Investigation of antifungal effect of flavonoids. 1 [hesperidin, naringin, phellodendroside, luteolin-7-glucoside, hipotethin-7-glucoside, quecetin, celastroside, amentoflavone; Botrytis cinerea, Trichoderma glaucum, Aspergillus fumigatus]
    • Z. Krolicki, and E. Lamer-Zarawska Investigation of antifungal effect of flavonoids. 1 [hesperidin, naringin, phellodendroside, luteolin-7-glucoside, hipotethin-7-glucoside, quecetin, celastroside, amentoflavone; Botrytis cinerea, Trichoderma glaucum, Aspergillus fumigatus] Herba Polonica 30 1984 53 57
    • (1984) Herba Polonica , vol.30 , pp. 53-57
    • Krolicki, Z.1    Lamer-Zarawska, E.2
  • 32
    • 77956474491 scopus 로고    scopus 로고
    • Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi
    • V. Lakshmi, S.K. Joseph, S. Srivastava, S.K. Verma, and et al. Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi Acta Trop. 116 2010 127 133
    • (2010) Acta Trop. , vol.116 , pp. 127-133
    • Lakshmi, V.1    Joseph, S.K.2    Srivastava, S.3    Verma, S.K.4
  • 33
    • 84865317606 scopus 로고    scopus 로고
    • Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: Enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori
    • Y.S. Lee, J.Y. Huh, S.H. Nam, S.K. Moon, and et al. Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori Food Chem. 135 2012 2253 2259
    • (2012) Food Chem. , vol.135 , pp. 2253-2259
    • Lee, Y.S.1    Huh, J.Y.2    Nam, S.H.3    Moon, S.K.4
  • 34
    • 84895076942 scopus 로고    scopus 로고
    • Current progress in antiviral strategies
    • Z. Lou, Y. Sun, and Z. Rao Current progress in antiviral strategies Trends Pharmacol. Sci. 35 2014 86 102
    • (2014) Trends Pharmacol. Sci. , vol.35 , pp. 86-102
    • Lou, Z.1    Sun, Y.2    Rao, Z.3
  • 35
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • C. Manach, G. Williamson, C. Morand, A. Scalbert, and et al. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies Am. J. Clin. Nutr. 81 2005 230S 242S
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 230S-242S
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4
  • 36
    • 36549050839 scopus 로고    scopus 로고
    • Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry
    • G. Mandalari, R.N. Bennett, G. Bisignano, D. Trombetta, and et al. Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry J. Appl. Microbiol. 103 2007 2056 2064
    • (2007) J. Appl. Microbiol. , vol.103 , pp. 2056-2064
    • Mandalari, G.1    Bennett, R.N.2    Bisignano, G.3    Trombetta, D.4
  • 37
    • 0030851756 scopus 로고    scopus 로고
    • Effect of flavonoids on daunomycin-induced toxicity in cultivated endothelial cells
    • M.F. Melzig, R. Loose, and G. Schonherr Effect of flavonoids on daunomycin-induced toxicity in cultivated endothelial cells Pharmazie 52 1997 793 796
    • (1997) Pharmazie , vol.52 , pp. 793-796
    • Melzig, M.F.1    Loose, R.2    Schonherr, G.3
  • 38
    • 0031238824 scopus 로고    scopus 로고
    • Antimicrobial action of propolis and some of its components: The effects on growth, membrane potential and motility of bacteria
    • O.K. Mirzoeva, R.N. Grishanin, and P.C. Calder Antimicrobial action of propolis and some of its components: the effects on growth, membrane potential and motility of bacteria Microbiol. Res. 152 1997 239 246
    • (1997) Microbiol. Res. , vol.152 , pp. 239-246
    • Mirzoeva, O.K.1    Grishanin, R.N.2    Calder, P.C.3
  • 39
    • 0021808955 scopus 로고
    • Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids
    • I. Mucsi, and B.M. Pragai Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids Experientia 41 1985 930 931
    • (1985) Experientia , vol.41 , pp. 930-931
    • Mucsi, I.1    Pragai, B.M.2
  • 40
    • 0031045050 scopus 로고    scopus 로고
    • Biological activities of the secondary metabolites isolated from Zieria smithii and Zanthoxylum elephantiasis on microorganisms and brine shrimps
    • S.K. Nazrul Islam, and M. Ahsan Biological activities of the secondary metabolites isolated from Zieria smithii and Zanthoxylum elephantiasis on microorganisms and brine shrimps Physiol. Res. 11 1997 64 66
    • (1997) Physiol. Res. , vol.11 , pp. 64-66
    • Nazrul Islam, S.K.1    Ahsan, M.2
  • 42
    • 84924298691 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: An updated review of their molecular mechanisms and experimental models
    • H. Parhiz, A. Roohbakhsh, F. Soltani, R. Rezaee, and et al. Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: an updated review of their molecular mechanisms and experimental models Physiol. Res. 29 2015 323 331
    • (2015) Physiol. Res. , vol.29 , pp. 323-331
    • Parhiz, H.1    Roohbakhsh, A.2    Soltani, F.3    Rezaee, R.4
  • 43
    • 84860451639 scopus 로고    scopus 로고
    • Hesperetin protects against oxidative stress related hepatic dysfunction by cadmium in rats
    • L. Pari, and K. Shagirtha Hesperetin protects against oxidative stress related hepatic dysfunction by cadmium in rats Exp. Toxicol. Pathol. 64 2012 513 520
    • (2012) Exp. Toxicol. Pathol. , vol.64 , pp. 513-520
    • Pari, L.1    Shagirtha, K.2
  • 44
    • 84875926063 scopus 로고    scopus 로고
    • Enzymatic modification enhances the protective activity of citrus flavonoids against alcohol-induced liver disease
    • H.-Y. Park, H.-D. Choi, H. Eom, and I. Choi Enzymatic modification enhances the protective activity of citrus flavonoids against alcohol-induced liver disease Food Chem. 139 2013 231 240
    • (2013) Food Chem. , vol.139 , pp. 231-240
    • Park, H.-Y.1    Choi, H.-D.2    Eom, H.3    Choi, I.4
  • 45
    • 43649093288 scopus 로고    scopus 로고
    • The potential influence of fruit polyphenols on colonic microflora and human gut health
    • S.G. Parkar, D.E. Stevenson, and M.A. Skinner The potential influence of fruit polyphenols on colonic microflora and human gut health Int. J. Food Microbiol. 124 2008 295 298
    • (2008) Int. J. Food Microbiol. , vol.124 , pp. 295-298
    • Parkar, S.G.1    Stevenson, D.E.2    Skinner, M.A.3
  • 46
    • 79954578979 scopus 로고    scopus 로고
    • Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice
    • A. Petrova, L.M. Davids, F. Rautenbach, and J.L. Marnewick Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice J. Photochem. Photobiol. B 103 2011 126 139
    • (2011) J. Photochem. Photobiol. B , vol.103 , pp. 126-139
    • Petrova, A.1    Davids, L.M.2    Rautenbach, F.3    Marnewick, J.L.4
  • 47
    • 84860546997 scopus 로고    scopus 로고
    • Protective effect of hesperidin, a citrus flavanoglycone, against gamma-radiation-induced tissue damage in Sprague-Dawley rats
    • K. Pradeep, K.C. Ko, M.H. Choi, J.A. Kang, and et al. Protective effect of hesperidin, a citrus flavanoglycone, against gamma-radiation-induced tissue damage in Sprague-Dawley rats J. Med. Food 15 2012 419 427
    • (2012) J. Med. Food , vol.15 , pp. 419-427
    • Pradeep, K.1    Ko, K.C.2    Choi, M.H.3    Kang, J.A.4
  • 48
    • 44149092363 scopus 로고    scopus 로고
    • Hesperidin a flavanoglycone protects against gamma-irradiation induced hepatocellular damage and oxidative stress in Sprague-Dawley rats
    • K. Pradeep, S.H. Park, and K.C. Ko Hesperidin a flavanoglycone protects against gamma-irradiation induced hepatocellular damage and oxidative stress in Sprague-Dawley rats Eur. J. Pharmacol. 587 2008 273 280
    • (2008) Eur. J. Pharmacol. , vol.587 , pp. 273-280
    • Pradeep, K.1    Park, S.H.2    Ko, K.C.3
  • 51
    • 84921630455 scopus 로고    scopus 로고
    • Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin - A mini-review
    • A. Roohbakhsh, H. Parhiz, F. Soltani, R. Rezaee, and et al. Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin - a mini-review Life Sci. 113 2014 1 6
    • (2014) Life Sci. , vol.113 , pp. 1-6
    • Roohbakhsh, A.1    Parhiz, H.2    Soltani, F.3    Rezaee, R.4
  • 52
    • 67650732727 scopus 로고    scopus 로고
    • Glucosyl hesperidin prevents influenza a virus replication in vitro by inhibition of viral sialidase
    • R.K. Saha, T. Takahashi, and T. Suzuki Glucosyl hesperidin prevents influenza a virus replication in vitro by inhibition of viral sialidase Biol. Pharm. Bull. 32 2009 1188 1192
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 1188-1192
    • Saha, R.K.1    Takahashi, T.2    Suzuki, T.3
  • 53
    • 84875231744 scopus 로고    scopus 로고
    • Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage
    • B.D. Sahu, M. Kuncha, G.J. Sindhura, and R. Sistla Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage Phytomedicine 20 2013 453 460
    • (2013) Phytomedicine , vol.20 , pp. 453-460
    • Sahu, B.D.1    Kuncha, M.2    Sindhura, G.J.3    Sistla, R.4
  • 54
    • 77957020511 scopus 로고    scopus 로고
    • Antifungal activity of natural and enzymatically-modified flavonoids isolated from citrus species
    • M.P. Salas, G. Céliz, H. Geronazzo, M. Daz, and et al. Antifungal activity of natural and enzymatically-modified flavonoids isolated from citrus species Food Chem. 124 2011 1411 1415
    • (2011) Food Chem. , vol.124 , pp. 1411-1415
    • Salas, M.P.1    Céliz, G.2    Geronazzo, H.3    Daz, M.4
  • 55
    • 84866548400 scopus 로고    scopus 로고
    • Efficacy of flavanones obtained from citrus residues to prevent patulin contamination
    • M.P. Salas, C.M. Reynoso, G. Céliz, M. Daz, and et al. Efficacy of flavanones obtained from citrus residues to prevent patulin contamination Food Res. Int. 48 2012 930 934
    • (2012) Food Res. Int. , vol.48 , pp. 930-934
    • Salas, M.P.1    Reynoso, C.M.2    Céliz, G.3    Daz, M.4
  • 56
    • 80053130244 scopus 로고    scopus 로고
    • Hesperetin, a citrus flavonone, protects potentially cadmium induced oxidative testicular dysfunction in rats
    • K. Shagirtha, and L. Pari Hesperetin, a citrus flavonone, protects potentially cadmium induced oxidative testicular dysfunction in rats Ecotoxicol. Environ. Saf. 74 2011 2105 2111
    • (2011) Ecotoxicol. Environ. Saf. , vol.74 , pp. 2105-2111
    • Shagirtha, K.1    Pari, L.2
  • 57
    • 84923539168 scopus 로고    scopus 로고
    • Hesperidin, a citrus bioflavonoid, ameliorates genotoxicity-induced by diazinon in human blood lymphocytes
    • M. Shokrzadeh, A. Ahmadi, S. Ramezaninejhad, and A. Shadboorestan Hesperidin, a citrus bioflavonoid, ameliorates genotoxicity-induced by diazinon in human blood lymphocytes Drug Res (Stuttg) 65 2015 57 60
    • (2015) Drug Res (Stuttg) , vol.65 , pp. 57-60
    • Shokrzadeh, M.1    Ahmadi, A.2    Ramezaninejhad, S.3    Shadboorestan, A.4
  • 58
    • 79952439247 scopus 로고    scopus 로고
    • Hesperetin protects testicular toxicity of doxorubicin in rat: Role of NFkappaB, p38 and caspase-3
    • P.P. Trivedi, D.N. Tripathi, and G.B. Jena Hesperetin protects testicular toxicity of doxorubicin in rat: role of NFkappaB, p38 and caspase-3 Food Chem. Toxicol. 49 2011 838 847
    • (2011) Food Chem. Toxicol. , vol.49 , pp. 838-847
    • Trivedi, P.P.1    Tripathi, D.N.2    Jena, G.B.3
  • 59
    • 79955598844 scopus 로고    scopus 로고
    • Kaempferol inhibits enterovirus 71 replication and internal ribosome entry site (IRES) activity through FUBP and HNRP proteins
    • F.J. Tsai, C.W. Lin, C.C. Lai, Y.C. Lan, and et al. Kaempferol inhibits enterovirus 71 replication and internal ribosome entry site (IRES) activity through FUBP and HNRP proteins Food Chem. 128 2011 312 322
    • (2011) Food Chem. , vol.128 , pp. 312-322
    • Tsai, F.J.1    Lin, C.W.2    Lai, C.C.3    Lan, Y.C.4
  • 60
    • 84928202515 scopus 로고    scopus 로고
    • Protective effect of alpha glucosyl hesperidin (G-hesperidin) on chronic vanadium induced testicular toxicity and sperm nuclear DNA damage in male Sprague Dawley rats
    • B. Vijaya Bharathi, G. Jaya Prakash, K.M. Krishna, C.H. Ravi Krishna, and et al. Protective effect of alpha glucosyl hesperidin (G-hesperidin) on chronic vanadium induced testicular toxicity and sperm nuclear DNA damage in male Sprague Dawley rats Andrologia 47 2015 568 578
    • (2015) Andrologia , vol.47 , pp. 568-578
    • Vijaya Bharathi, B.1    Jaya Prakash, G.2    Krishna, K.M.3    Ravi Krishna, C.H.4
  • 61
    • 0017840637 scopus 로고
    • Antiviral activity of plant components. 1st communication: Flavonoids
    • A. Wacker, and H.G. Eilmes Antiviral activity of plant components. 1st communication: flavonoids Arzneimittelforschung 28 1978 347 350
    • (1978) Arzneimittelforschung , vol.28 , pp. 347-350
    • Wacker, A.1    Eilmes, H.G.2
  • 62
    • 38049025190 scopus 로고    scopus 로고
    • In vitro antioxidant and antimicrobial activities of the extract of Pericarpium citri reticulatae of a new citrus cultivar and its main flavonoids
    • Z. Yi, Y. Yu, Y. Liang, and B. Zeng In vitro antioxidant and antimicrobial activities of the extract of Pericarpium citri reticulatae of a new citrus cultivar and its main flavonoids LWT-Food Sci. Technol. 41 2008 597 603
    • (2008) LWT-Food Sci. Technol. , vol.41 , pp. 597-603
    • Yi, Z.1    Yu, Y.2    Liang, Y.3    Zeng, B.4
  • 63
    • 2442433731 scopus 로고    scopus 로고
    • Double-strand break of giant DNA: Protection by glucosyl-hesperidin as evidenced through direct observation on individual DNA molecules
    • Y. Yoshikawa, M. Suzuki, N. Yamada, and K. Yoshikawa Double-strand break of giant DNA: protection by glucosyl-hesperidin as evidenced through direct observation on individual DNA molecules FEBS Lett. 566 2004 39 42
    • (2004) FEBS Lett. , vol.566 , pp. 39-42
    • Yoshikawa, Y.1    Suzuki, M.2    Yamada, N.3    Yoshikawa, K.4
  • 64
    • 84938960227 scopus 로고    scopus 로고
    • Molecular interactions of flavonoids to hyaluronidase: Insights from spectroscopic and molecular modeling studies
    • In press
    • H.J. Zeng, J. Ma, R. Yang, Y. Jing, and et al. Molecular interactions of flavonoids to hyaluronidase: insights from spectroscopic and molecular modeling studies J. Fluoresc. 2015 In press
    • (2015) J. Fluoresc.
    • Zeng, H.J.1    Ma, J.2    Yang, R.3    Jing, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.