Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage

Phytomedicine

Volumn 20, Issue 5, 2013, Pages 453-460

  Sahu, Bidya Dhar ^a   Kuncha, Madhusudana ^a   Sindhura, G Jeevana ^b   Sistla, Ramakrishna ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b JSS COLLEGE OF PHARMACY   (India)

Author keywords

Apoptosis; Cisplatin; Hesperidin; Inflammation; Nephrotoxicity; Oxidative stress

Indexed keywords

ASCORBIC ACID; CASPASE 3; CATALASE; CISPLATIN; CREATININE; DNA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HESPERIDIN; LIPID; MALONALDEHYDE; MYELOPEROXIDASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DNA DAMAGE; DRUG EFFICACY; ENZYME ACTIVITY; HISTOPATHOLOGY; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; LEUKOCYTE; LIPID PEROXIDATION; NEPHRITIS; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; ANIMALS; APOPTOSIS; BLOOD UREA NITROGEN; CASPASE 3; CISPLATIN; CREATININE; CYTOPROTECTION; DNA DAMAGE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HESPERIDIN; INFLAMMATION; KIDNEY; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; NITRIC OXIDE; OXIDATIVE STRESS; PEROXIDASE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 84875231744     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.12.001     Document Type: Article

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