Differential epigenetic and transcriptional response of the skeletal muscle carnitine palmitoyltransferase 1B (CPT1B) gene to lipid exposure with obesity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 309, Issue 4, 2015, Pages E345-E356

  Maples, Jill M ^a   Brault, Jeffrey J ^a,b   Witczak, Carol A ^a,b   Park, Sanghee ^a   Hubal, Monica J ^c   Weber, Todd M ^a   Houmard, Joseph A ^a   Shewchuk, Brian M ^b  

^a EAST CAROLINA UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

DNA methylation; Gene regulation; Lipid metabolism; Obesity; Skeletal muscle

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; CARNITINE PALMITOYLTRANSFERASE IBETA; CYTOSINE; FATTY ACID; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HISTONE H4; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; UPSTREAM STIMULATORY FACTOR; CARNITINE PALMITOYLTRANSFERASE; CPT1B PROTEIN, HUMAN; FAT INTAKE;

ADULT; ARTICLE; BINDING AFFINITY; CATABOLISM; COMPARATIVE STUDY; CONCENTRATION PROCESS; CONTROLLED STUDY; DNA METHYLATION; ENZYME MECHANISM; EPIGENETICS; FAT INTAKE; FATTY ACID OXIDATION; FEMALE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; INTRINSIC ACTIVITY; LIPID METABOLISM; MITOCHONDRIAL MEMBRANE; MUSCLE BIOPSY; OBESITY; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; SKELETAL MUSCLE; TRANSCRIPTION INITIATION; UPREGULATION; CASE CONTROL STUDY; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MORBID OBESITY; PATHOLOGY; PHARMACOLOGY; YOUNG ADULT;

ADULT; CARNITINE O-PALMITOYLTRANSFERASE; CASE-CONTROL STUDIES; CELLS, CULTURED; DIETARY FATS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LIPIDS; MUSCLE, SKELETAL; OBESITY, MORBID; TRANSCRIPTION, GENETIC; YOUNG ADULT;

EID: 84939444502     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00505.2014     Document Type: Article

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