TiO2 nanoparticles induce insulin resistance in liver-derived cells both directly and via macrophage activation

Nanotoxicology

Volumn 6, Issue 8, 2012, Pages 804-812

  Gurevitch, Diana ^a   Shuster Meiseles, Timor ^a   Nov, Ori ^b   Zick, Yehiel ^a   Rudich, Assaf ^a,b   Rudich, Yinon ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Inflammation; Insulin resistance; Liver; Macrophages; TiO2

Indexed keywords

GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NANOPARTICLE; STRESS ACTIVATED PROTEIN KINASE; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA; METAL NANOPARTICLE; TITANIUM;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; EXPOSURE; GENE EXPRESSION; GLYCOGEN SYNTHESIS; INFLAMMATION; INSULIN RESISTANCE; LIVER CELL; MACROPHAGE ACTIVATION; MOUSE; NANOTOXICOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CULTURE MEDIUM; DRUG EFFECT; LIVER; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; GLYCOGEN; INSULIN; INSULIN RESISTANCE; LIVER; MACROPHAGE ACTIVATION; METAL NANOPARTICLES; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TITANIUM;

EID: 84869047017     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.625128     Document Type: Article

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