Role of glutathione peroxidase 4 in glutamate-induced oxytosis in the retina

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Sakai, Osamu ^a,b   Uchida, Takatoshi ^a,b   Roggia, Murilo F ^a   Imai, Hirotaka ^c   Ueta, Takashi ^a   Amano, Shiro ^d,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b SENJU PHARMACEUTICAL CO LTD   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d Inoue Eye Hospital   (Japan)

^e Miyata Eye Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; LACTATE DEHYDROGENASE; LIPID; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; SMALL INTERFERING RNA; GLUTATHIONE PEROXIDASE; MESSENGER RNA; PHOSPHOLIPID-HYDROPEROXIDE GLUTATHIONE PEROXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; LIPID PEROXIDATION; MOUSE; NEUROTOXICITY; NONHUMAN; OXYTOSIS; PROTEIN EXPRESSION; RAT; RETINA; RETINA GANGLION CELL; TUNEL ASSAY; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; KNOCKOUT MOUSE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

MUS; RATTUS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; IMMUNOENZYME TECHNIQUES; LIPID PEROXIDATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RETINA; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84939218636     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130467     Document Type: Article

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