Chaperone-mediated autophagy and neurodegeneration: connections, mechanisms, and therapeutic implications

Neuroscience Bulletin

Volumn 31, Issue 4, 2015, Pages 407-415

  Liu, Xiaolei ^a,b   Huang, Sihua ^b,c   Wang, Xingqin ^b,d   Tang, Beisha ^a   Li, Wenming ^b   Mao, Zixu ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

autophagy; chaperone mediated autophagy; mutant proteins; neurodegenerative disorder; Parkinson s disease; risk factors; therapeutic target

Indexed keywords

ALPHA SYNUCLEIN; GLYCOPROTEIN; HEAT SHOCK COGNATE PROTEIN 70; LEUCINE RICH REPEAT KINASE 2; LYSOSOMAL MEMBRANE GLYCOPROTEIN; NEUROTOXIN; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG; CHAPERONE;

AGING; AMINO ACID SEQUENCE; CHAPERONE-MEDIATED AUTOPHAGY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; HUMAN; LYSOSOME MEMBRANE; MEMBRANE; MOLECULAR WEIGHT; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; REVIEW; SUBSTANTIA NIGRA PARS COMPACTA; ANIMAL; AUTOPHAGY; BRAIN; LYSOSOME; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; BRAIN; HUMANS; LYSOSOMES; MOLECULAR CHAPERONES; NEURODEGENERATIVE DISEASES;

EID: 84939000739     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-015-1542-8     Document Type: Review

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