-
1
-
-
77953641282
-
Shepherding AKT and androgen receptor by Ack1 tyrosine kinase
-
Mahajan K, Mahajan NP. Shepherding AKT and androgen receptor by Ack1 tyrosine kinase. J Cell Physiol 2010; 224: 327-333.
-
(2010)
J Cell Physiol
, vol.224
, pp. 327-333
-
-
Mahajan, K.1
Mahajan, N.P.2
-
2
-
-
84862103119
-
PI3K-independent AKT activation in cancers: A treasure trove for novel therapeutics
-
Mahajan K, Mahajan NP. PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics. J Cell Physiol 2012; 227: 3178-3184.
-
(2012)
J Cell Physiol
, vol.227
, pp. 3178-3184
-
-
Mahajan, K.1
Mahajan, N.P.2
-
3
-
-
0027235324
-
A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42
-
Manser E, Leung T, Salihuddin H, Tan L, Lim L. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42. Nature 1993; 363: 364-367.
-
(1993)
Nature
, vol.363
, pp. 364-367
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Tan, L.4
Lim, L.5
-
4
-
-
28544438918
-
Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: Role of Ack1 in polyubiquitination of tumor suppressor Wwox
-
Mahajan NP, Whang YE, Mohler JL, Earp HS. Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. Cancer Res 2005; 65: 10514-10523.
-
(2005)
Cancer Res
, vol.65
, pp. 10514-10523
-
-
Mahajan, N.P.1
Whang, Y.E.2
Mohler, J.L.3
Earp, H.S.4
-
5
-
-
34347263425
-
Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation
-
Mahajan NP, Liu Y, Majumder S, Warren MR, Parker CE, Mohler JL et al. Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation. Proc Natl Acad Sci USA 2007; 104: 8438-8443.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8438-8443
-
-
Mahajan, N.P.1
Liu, Y.2
Majumder, S.3
Warren, M.R.4
Parker, C.E.5
Mohler, J.L.6
-
7
-
-
84872286255
-
Ack1: Activation and regulation by allostery
-
Gajiwala KS, Maegley K, Ferre R, He YA, Yu X. Ack1: activation and regulation by allostery. PLoS ONE 2013; 8: e53994.
-
(2013)
PLoS ONE
, vol.8
-
-
Gajiwala, K.S.1
Maegley, K.2
Ferre, R.3
He, Y.A.4
Yu, X.5
-
8
-
-
84864121296
-
Regulation of ack-family nonreceptor tyrosine kinases
-
Prieto-Echague V, Miller WT. Regulation of ack-family nonreceptor tyrosine kinases. J Signal Transduct 2011; 2011: 742372.
-
(2011)
J Signal Transduct
, vol.2011
, pp. 742372
-
-
Prieto-Echague, V.1
Miller, W.T.2
-
9
-
-
77951210920
-
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1
-
Prieto-Echague V, Gucwa A, Craddock BP, Brown DA, Miller WT. Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. J Biol Chem 2010; 285: 10605-10615.
-
(2010)
J Biol Chem
, vol.285
, pp. 10605-10615
-
-
Prieto-Echague, V.1
Gucwa, A.2
Craddock, B.P.3
Brown, D.A.4
Miller, W.T.5
-
10
-
-
84863224894
-
The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1)
-
Lin Q, Wang J, Childress C, Yang W. The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1). Biochem J 2012; 445: 255-264.
-
(2012)
Biochem J
, vol.445
, pp. 255-264
-
-
Lin, Q.1
Wang, J.2
Childress, C.3
Yang, W.4
-
11
-
-
77958479041
-
Regulation of Ack1 localization and activity by the amino-terminal SAM domain
-
Prieto-Echague V, Gucwa A, Brown DA, Miller WT. Regulation of Ack1 localization and activity by the amino-terminal SAM domain. BMC Biochem 2010; 11: 42.
-
(2010)
BMC Biochem
, vol.11
, pp. 42
-
-
Prieto-Echague, V.1
Gucwa, A.2
Brown, D.A.3
Miller, W.T.4
-
12
-
-
77954607192
-
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
-
Mahajan K, Coppola D, Challa S, Fang B, Chen YA, Zhu W et al. Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. PLoS One 2010; 5: e9646.
-
(2010)
PLoS One
, vol.5
-
-
Mahajan, K.1
Coppola, D.2
Challa, S.3
Fang, B.4
Chen, Y.A.5
Zhu, W.6
-
13
-
-
77954584067
-
Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity
-
Mahajan K, Challa S, Coppola D, Lawrence H, Luo Y, Gevariya H et al. Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Prostate 2010; 70: 1274-1285.
-
(2010)
Prostate
, vol.70
, pp. 1274-1285
-
-
Mahajan, K.1
Challa, S.2
Coppola, D.3
Lawrence, H.4
Luo, Y.5
Gevariya, H.6
-
14
-
-
33947148666
-
Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation
-
Shen F, Lin Q, Gu Y, Childress C, Yang W. Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation. Mol Biol Cell 2007; 18: 732-742.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 732-742
-
-
Shen, F.1
Lin, Q.2
Gu, Y.3
Childress, C.4
Yang, W.5
-
15
-
-
65549156107
-
Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2
-
Chan W, Tian R, Lee YF, Sit ST, Lim L, Manser E. Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2. J Biol Chem 2009; 284: 8185-8194.
-
(2009)
J Biol Chem
, vol.284
, pp. 8185-8194
-
-
Chan, W.1
Tian, R.2
Lee, Y.F.3
Sit, S.T.4
Lim, L.5
Manser, E.6
-
16
-
-
84896877112
-
The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome
-
Jones S, Cunningham DL, Rappoport JZ, Heath JK. The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome. J Cell Sci 2014; 127: 994-1006.
-
(2014)
J Cell Sci
, vol.127
, pp. 994-1006
-
-
Jones, S.1
Cunningham, D.L.2
Rappoport, J.Z.3
Heath, J.K.4
-
17
-
-
84885599237
-
SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation
-
Buchwald M, Pietschmann K, Brand P, Gunther A, Mahajan NP, Heinzel T et al. SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation. Oncogene 2012; 32: 4913-4920.
-
(2012)
Oncogene
, vol.32
, pp. 4913-4920
-
-
Buchwald, M.1
Pietschmann, K.2
Brand, P.3
Gunther, A.4
Mahajan, N.P.5
Heinzel, T.6
-
18
-
-
84876149637
-
SIAH proteins: Critical roles in leukemogenesis
-
Kramer OH, Stauber RH, Bug G, Hartkamp J, Knauer SK. SIAH proteins: critical roles in leukemogenesis. Leukemia 2013; 27: 792-802.
-
(2013)
Leukemia
, vol.27
, pp. 792-802
-
-
Kramer, O.H.1
Stauber, R.H.2
Bug, G.3
Hartkamp, J.4
Knauer, S.K.5
-
19
-
-
23744511569
-
Expression, synaptic localization, and developmental regulation of Ack1/ Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain
-
Urena JM, La Torre A, Martinez A, Lowenstein E, Franco N, Winsky-Sommerer R et al. Expression, synaptic localization, and developmental regulation of Ack1/ Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain. J Comp Neurol 2005; 490: 119-132.
-
(2005)
J Comp Neurol
, vol.490
, pp. 119-132
-
-
Urena, J.M.1
La Torre, A.2
Martinez, A.3
Lowenstein, E.4
Franco, N.5
Winsky-Sommerer, R.6
-
20
-
-
33748369138
-
Expression pattern of ACK1 tyrosine kinase during brain development in the mouse
-
La Torre A, del Rio JA, Soriano E, Urena JM. Expression pattern of ACK1 tyrosine kinase during brain development in the mouse. Gene Expr Patterns 2006; 6: 886-892.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 886-892
-
-
La Torre, A.1
Del Rio, J.A.2
Soriano, E.3
Urena, J.M.4
-
21
-
-
84879723311
-
A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching
-
La Torre A, del Mar Masdeu M, Cotrufo T, Moubarak RS, del Rio JA, Comella JX et al. A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching. Cell Death Dis 2013; 4: e602.
-
(2013)
Cell Death Dis
, vol.4
, pp. e602
-
-
La Torre, A.1
Del Mar Masdeu, M.2
Cotrufo, T.3
Moubarak, R.S.4
Del Rio, J.A.5
Comella, J.X.6
-
22
-
-
84891519543
-
Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy
-
Hitomi Y, Heinzen EL, Donatello S, Dahl HH, Damiano JA, McMahon JM et al. Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy. Ann Neurol 2013; 74: 496-501.
-
(2013)
Ann Neurol
, vol.74
, pp. 496-501
-
-
Hitomi, Y.1
Heinzen, E.L.2
Donatello, S.3
Dahl, H.H.4
Damiano, J.A.5
McMahon, J.M.6
-
23
-
-
33745597344
-
Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli
-
Galisteo ML, Yang Y, Urena J, Schlessinger J. Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. Proc Natl Acad Sci USA 2006; 103: 9796-9801.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9796-9801
-
-
Galisteo, M.L.1
Yang, Y.2
Urena, J.3
Schlessinger, J.4
-
24
-
-
27644436744
-
Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1
-
van der Horst EH, Degenhardt YY, Strelow A, Slavin A, Chinn L, Orf J et al. Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proc Natl Acad Sci USA 2005; 102: 15901-15906.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15901-15906
-
-
Van Der Horst, E.H.1
Degenhardt, Y.Y.2
Strelow, A.3
Slavin, A.4
Chinn, L.5
Orf, J.6
-
25
-
-
84962051602
-
ACK1/TNK2 tyrosine kinase:An emerging target for cancer therapeutics
-
Mahajan K, Mahajan NP. ACK1/TNK2 tyrosine kinase:An emerging target for cancer therapeutics. AACR Educ Book 2014; 2014: 6.
-
(2014)
AACR Educ Book
, vol.2014
, pp. 6
-
-
Mahajan, K.1
Mahajan, N.P.2
-
26
-
-
84893679655
-
TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer
-
Shinmura K, Kiyose S, Nagura K, Igarashi H, Inoue Y, Nakamura S et al. TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer. J Surg Oncol 2013; 109: 189-197.
-
(2013)
J Surg Oncol
, vol.109
, pp. 189-197
-
-
Shinmura, K.1
Kiyose, S.2
Nagura, K.3
Igarashi, H.4
Inoue, Y.5
Nakamura, S.6
-
27
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007; 129: 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
28
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005; 24: 7410-7425.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
29
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang H, Tindall DJ. Dynamic FoxO transcription factors. J Cell Sci 2007; 120: 2479-2487.
-
(2007)
J Cell Sci
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
30
-
-
84859048356
-
Ack1 tyrosine kinase activation correlates with pancreatic cancer progression
-
Mahajan K, Coppola D, Chen YA, Zhu W, Lawrence HR, Lawrence NJ et al. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol 2012; 180: 1386-1393.
-
(2012)
Am J Pathol
, vol.180
, pp. 1386-1393
-
-
Mahajan, K.1
Coppola, D.2
Chen, Y.A.3
Zhu, W.4
Lawrence, H.R.5
Lawrence, N.J.6
-
31
-
-
84863657989
-
Drosophila activated Cdc42 kinase has an anti-apoptotic function
-
Schoenherr JA, Drennan JM, Martinez JS, Chikka MR, Hall MC, Chang HC et al. Drosophila activated Cdc42 kinase has an anti-apoptotic function. PLoS Genet 2012; 8: e1002725.
-
(2012)
PLoS Genet
, vol.8
-
-
Schoenherr, J.A.1
Drennan, J.M.2
Martinez, J.S.3
Chikka, M.R.4
Hall, M.C.5
Chang, H.C.6
-
32
-
-
24744471465
-
Regulation of androgen receptor levels: Implications for prostate cancer progression and therapy
-
Burnstein KL. Regulation of androgen receptor levels: implications for prostate cancer progression and therapy. J Cell Biochem 2005; 95: 657-669.
-
(2005)
J Cell Biochem
, vol.95
, pp. 657-669
-
-
Burnstein, K.L.1
-
33
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004; 10: 33-39.
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
-
34
-
-
67650480389
-
Cistromics of hormone-dependent cancer
-
Lupien M, Brown M. Cistromics of hormone-dependent cancer. Endocr Relat Cancer 2009; 16: 381-389.
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 381-389
-
-
Lupien, M.1
Brown, M.2
-
35
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev 2001; 1: 34-45.
-
(2001)
Nat Rev
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
36
-
-
20444403792
-
The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: Modifications to the androgen receptor
-
Edwards J, Bartlett JM. The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: Modifications to the androgen receptor. BJU Int 2005; 95: 1320-1326.
-
(2005)
BJU Int
, vol.95
, pp. 1320-1326
-
-
Edwards, J.1
Bartlett, J.M.2
-
37
-
-
84862693127
-
Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer
-
Mahajan K, Coppola D, Rawal B, Chen YA, Lawrence HR, Engelman RW et al. Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. J Biol Chem 2012; 287: 22112-22122.
-
(2012)
J Biol Chem
, vol.287
, pp. 22112-22122
-
-
Mahajan, K.1
Coppola, D.2
Rawal, B.3
Chen, Y.A.4
Lawrence, H.R.5
Engelman, R.W.6
-
38
-
-
34547838420
-
PTEN, more than the AKT pathway
-
Blanco-Aparicio C, Renner O, Leal JF, Carnero A. PTEN, more than the AKT pathway. Carcinogenesis 2007; 28: 1379-1386.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1379-1386
-
-
Blanco-Aparicio, C.1
Renner, O.2
Leal, J.F.3
Carnero, A.4
-
40
-
-
34548248572
-
Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
-
Green KA, Carroll JS. Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nat Rev Cancer 2007; 7: 713-722.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 713-722
-
-
Green, K.A.1
Carroll, J.S.2
-
41
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998; 90: 1371-1388.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Redmond, C.K.4
Kavanah, M.5
Cronin, W.M.6
-
42
-
-
27944492407
-
Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
-
Fisher B, Costantino JP, Wickerham DL, Cecchini RS, Cronin WM, Robidoux A et al. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 2005; 97: 1652-1662.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1652-1662
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Cecchini, R.S.4
Cronin, W.M.5
Robidoux, A.6
-
43
-
-
0028965397
-
Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer
-
Howell A, DeFriend D, Robertson J, Blamey R, Walton P. Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer. Lancet 1995; 345: 29-30.
-
(1995)
Lancet
, vol.345
, pp. 29-30
-
-
Howell, A.1
DeFriend, D.2
Robertson, J.3
Blamey, R.4
Walton, P.5
-
44
-
-
0035101145
-
Cellular and molecular pharmacology of antiestrogen action and resistance
-
Clarke R, Leonessa F, Welch JN, Skaar TC. Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol Rev 2001; 53: 25-71.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 25-71
-
-
Clarke, R.1
Leonessa, F.2
Welch, J.N.3
Skaar, T.C.4
-
45
-
-
84907833705
-
ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1
-
Mahajan K, Lawrence HR, Lawrence NJ, Mahajan NP. ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1. J Biol Chem 2014; 289: 28179-28191.
-
(2014)
J Biol Chem
, vol.289
, pp. 28179-28191
-
-
Mahajan, K.1
Lawrence, H.R.2
Lawrence, N.J.3
Mahajan, N.P.4
-
46
-
-
0348049845
-
Incidence, mechanism and prognostic value of activated AKT in pancreas cancer
-
Schlieman MG, Fahy BN, Ramsamooj R, Beckett L, Bold RJ. Incidence, mechanism and prognostic value of activated AKT in pancreas cancer. Br J Cancer 2003; 89: 2110-2115.
-
(2003)
Br J Cancer
, vol.89
, pp. 2110-2115
-
-
Schlieman, M.G.1
Fahy, B.N.2
Ramsamooj, R.3
Beckett, L.4
Bold, R.J.5
-
47
-
-
0036949812
-
Differential mechanisms of constitutive Akt/PKB activation and its influence on gene expression in pancreatic cancer cells
-
Matsumoto J, Kaneda M, Tada M, Hamada J, Okushiba S, Kondo S et al. Differential mechanisms of constitutive Akt/PKB activation and its influence on gene expression in pancreatic cancer cells. Jpn J Cancer Res 2002; 93: 1317-1326.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 1317-1326
-
-
Matsumoto, J.1
Kaneda, M.2
Tada, M.3
Hamada, J.4
Okushiba, S.5
Kondo, S.6
-
48
-
-
15644379076
-
Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary
-
Sakurada A, Suzuki A, Sato M, Yamakawa H, Orikasa K, Uyeno S et al. Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary. Jpn J Cancer Res 1997; 88: 1025-1028.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 1025-1028
-
-
Sakurada, A.1
Suzuki, A.2
Sato, M.3
Yamakawa, H.4
Orikasa, K.5
Uyeno, S.6
-
49
-
-
84877608004
-
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML
-
Maxson JE, Gotlib J, Pollyea DA, Fleischman AG, Agarwal A, Eide CA et al. Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML. N Engl J Med 2013; 368: 1781-1790.
-
(2013)
N Engl J Med
, vol.368
, pp. 1781-1790
-
-
Maxson, J.E.1
Gotlib, J.2
Pollyea, D.A.3
Fleischman, A.G.4
Agarwal, A.5
Eide, C.A.6
-
50
-
-
84881668744
-
ACK1 tyrosine kinase: Targeted inhibition to block cancer cell proliferation
-
Mahajan K, Mahajan NP. ACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferation. Cancer Lett 2013; 338: 185-192.
-
(2013)
Cancer Lett
, vol.338
, pp. 185-192
-
-
Mahajan, K.1
Mahajan, N.P.2
-
51
-
-
77953229511
-
Dasatinib inhibits sitespecific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases
-
Liu Y, Karaca M, Zhang Z, Gioeli D, Earp HS, Whang YE. Dasatinib inhibits sitespecific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases. Oncogene 2010; 29: 3208-3216.
-
(2010)
Oncogene
, vol.29
, pp. 3208-3216
-
-
Liu, Y.1
Karaca, M.2
Zhang, Z.3
Gioeli, D.4
Earp, H.S.5
Whang, Y.E.6
-
52
-
-
84892711477
-
Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer
-
Tan DS, Haaland B, Gan JM, Tham SC, Sinha I, Tan EH et al. Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer. Mol Cancer 2014; 13: 13.
-
(2014)
Mol Cancer
, vol.13
, pp. 13
-
-
Tan, D.S.1
Haaland, B.2
Gan, J.M.3
Tham, S.C.4
Sinha, I.5
Tan, E.H.6
-
53
-
-
33947573110
-
Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR
-
DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Buchanan JL et al. Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR. Bioorg Med Chem Lett 2007; 17: 2305-2309.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2305-2309
-
-
DiMauro, E.F.1
Newcomb, J.2
Nunes, J.J.3
Bemis, J.E.4
Boucher, C.5
Buchanan, J.L.6
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