Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary

Japanese Journal of Cancer Research

Volumn 88, Issue 11, 1997, Pages 1025-1028

  Sakurada, Akira ^a,b   Suzuki, Akihiko ^a   Sato, Masami ^a,b   Yamakawa, Hiromitsu ^a   Orikasa, Kazuhiko ^a   Uyeno, Shinji ^a   Ono, Tetsuya ^a   Ohuchi, Noriaki ^a   Fujimura, Shigefumi ^b   Horii, Akira ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Glioblastoma multiforme; PTEN MMAC1 gene; Somatic mutation

Indexed keywords

DNA;

ARTICLE; ASTROCYTOMA; BREAST CANCER; CANCER GENETICS; CONTROLLED STUDY; FRAMESHIFT MUTATION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; KIDNEY CANCER; KIDNEY CARCINOMA; LUNG CANCER; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; OVARY CANCER; PANCREAS CANCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

EID: 15644379076     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00324.x     Document Type: Article

References (11)

1. Walker, A. E., Robins, M. and Weinfeld, F. D. Epidemiology of brain tumors: the national survey of intracranial neoplasms. Neurology, 35, 219-226 (1985).
2. Kuratsu, J. and Ushio, Y. Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto Prefecture in the southern part of Japan. J. Neurosurg., 84, 946-950 (1996).
3. Ekstrand, A. J., James, C. D., Cavenee, W. K., Seliger, B., Pettersson, R. F. and Collins, V. P. Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res., 51, 2164-2172 (1991).
4. Louis, D. N. and Gusella, J. F. A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet., 11, 412-415 (1995).
5. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rdgers, L., Mccombie, R., Bingner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H. and Parsons, R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275, 1943-1947 (1997).
6. Steck, P. M., Perterhouse, M. A., Jasser, S. A., Yung, W. K. A., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C., Hu, R., Swedlund, B., Teng, D. H. F. and Tavigian, S. V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet., 15, 356-362 (1997).
7. Sato, T., Tanigami, A., Yamakawa, K., Akiyama, F., Kasumi, F., Sakamoto, G. and Nakamura, Y. Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res., 50, 7184-7189 (1990).
8. Orita, M., Suzuki, Y., Sekiya, T. and Hayashi, K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics, 5, 874-879 (1989).
9. Mayama, T., Mori, T., Abe, K., Sasano, H., Nishihira, T. and Horii, A. Analysis of the p53 gene mutations in patients with multiple primary cancers of the esophagus. Eur. J. Surg. Oncol., 23, 298-303 (1997).
10. Hattori, M. and Sakaki, Y. Dideoxy sequencing method using denatured plasmid templates. Anal. Biochem., 152, 232-238 (1986).
11. Sanger, F., Nicklen, S. and Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74, 5463-5467 (1977).