Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1

Journal of Biological Chemistry

Volumn 285, Issue 14, 2010, Pages 10605-10615

  Prieto Echagüe, Victoria ^a   Gucwa, Azad ^b   Craddock, Barbara P ^a   Brown, Deborah A ^b   Miller, W Todd ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHOSPHORYLATION; CANCER TISSUES; CANCER-ASSOCIATED MUTATIONS; CELL MIGRATION; CELL SURVIVAL; HYDROPHOBIC RESIDUES; IMMUNE COMPLEX; INTRAMOLECULAR INTERACTIONS; KINASE ASSAYS; KINASE DOMAINS; MAMMALIAN CELLS; N-TERMINALS; POINT MUTATIONS; TUMORIGENESIS; TYROSINE KINASE;

AMINO ACIDS; BIOASSAY; CYTOLOGY; MAMMALS; PHOSPHATASES;

COMPLEXATION;

NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE ACK1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; DEREGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; MISSENSE MUTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; COS CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASMS; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 77951210920     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.060459     Document Type: Article

References (53)

1. Manser, E., Leung, T., Salihuddin, H., Tan, L., and Lim, L. (1993) Nature 363, 364-367
2. Hoehn, G. T., Stokland, T., Amin, S., Ramírez, M., Hawkins, A. L., Griffin, C. A., Small, D., and Civin, C. I. (1996) Oncogene 12, 903-913
3. Hopper, N. A., Lee, J., and Sternberg, P. W. (2000) Mol. Cell 6, 65-75
4. Sem, K. P., Zahedi, B., Tan, I., Deak, M., Lim, L., and Harden, N. (2002) Mol. Cell Biol. 22, 3685-3697
5. Galisteo, M. L., Yang, Y., Ureña, J., and Schlessinger, J. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 9796-9801
6. Teo, M., Tan, L., Lim, L., and Manser, E. (2001) J. Biol. Chem. 276, 18392-18398
7. Shen, F., Lin, Q., Gu, Y., Childress, C., and Yang, W. (2007) Mol. Biol. Cell 18, 732-742
8. Zhang, X., Pickin, K. A., Bose, R., Jura, N., Cole, P. A., and Kuriyan, J. (2007) Nature 450, 741-744
9. van der Horst, E. H., Degenhardt, Y. Y., Strelow, A., Slavin, A., Chinn, L., Orf, J., Rong, M., Li, S., See, L. H., Nguyen, K. Q., Hoey, T., Wesche, H., and Powers, S. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 15901-15906
10. Nur-E-Kamal, A., Zhang, A., Keenan, S. M., Wang, X. I., Seraj, J., Satoh, T., Meiners, S., and Welsh, W. J. (2005) Mol. Cancer Res. 3, 297-305
11. Mahajan, N. P., Whang, Y. E., Mohler, J. L., and Earp, H. S. (2005) Cancer Res. 65, 10514-10523
12. Mahajan, N. P., Liu, Y., Majumder, S., Warren, M. R., Parker, C. E., Mohler, J. L., Earp, H. S., and Whang, Y. E. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 8438-8443
13. Yang, W., Lin, Q., Guan, J. L., and Cerione, R. A. (1999) J. Biol. Chem. 274, 8524-8530
14. Linseman, D. A., Heidenreich, K. A., and Fisher, S. K. (2001) J. Biol. Chem. 276, 5622-5628
15. Yang, W., and Cerione, R. A. (1997) J. Biol. Chem. 272, 24819-24824
16. Kato-Stankiewicz, J., Ueda, S., Kataoka, T., Kaziro, Y., and Satoh, T. (2001) Biochem. Biophys. Res. Commun. 284, 470-477
17. Eisenmann, K. M., McCarthy, J. B., Simpson, M. A., Keely, P. J., Guan, J. L., Tachibana, K., Lim, L., Manser, E., Furcht, L. T., and Iida, J. (1999) Nat. Cell Biol. 1, 507-513
18. Modzelewska, K., Newman, L. P., Desai, R., and Keely, P. J. (2006) J. Biol. Chem. 281, 37527-37535
19. Yokoyama, N., Lougheed, J., and Miller, W. T. (2005) J. Biol. Chem. 280, 42219-42226
20. Yeow-Fong, L., Lim, L., and Manser, E. (2005) FEBS Lett. 579, 5040-5048
21. Yokoyama, N., and Miller, W. T. (2003) J. Biol. Chem. 278, 47713-47723
22. Satoh, T., Kato, J., Nishida, K., and Kaziro, Y. (1996) FEBS Lett. 386, 230-234
23. Chan, W., Tian, R., Lee, Y. F., Sit, S. T., Lim, L., and Manser, E. (2009) J. Biol. Chem. 284, 8185-8194
24. Grøvdal, L. M., Johannessen, L. E., Rødland, M. S., Madshus, I. H., and Stang, E. (2008) Exp. Cell Res. 314, 1292-1300
25. Yang, W., Lo, C. G., Dispenza, T., and Cerione, R. A. (2001) J. Biol. Chem. 276, 17468-17473
26. Childress, C., Lin, Q., and Yang, W. (2006) Biochem. J. 394, 693-698
27. Huse, M., and Kuriyan, J. (2002) Cell 109, 275-282
28. Sicheri, F., Moarefi, I., and Kuriyan, J. (1997) Nature 385, 602-609
29. Xu, W., Harrison, S. C., and Eck, M. J. (1997) Nature 385, 595-602
30. Liu, X., Brodeur, S. R., Gish, G., Songyang, Z., Cantley, L. C., Laudano, A. P., and Pawson, T. (1993) Oncogene 8, 1119-1126
31. Alexandropoulos, K., and Baltimore, D. (1996) Genes Dev. 10, 1341-1355
32. Briggs, S. D., Sharkey, M., Stevenson, M., and Smithgall, T. E. (1997) J. Biol. Chem. 272, 17899-17902
33. Moarefi, I., LaFevre-Bernt, M., Sicheri, F., Huse, M., Lee, C. H., Kuriyan, J., and Miller, W. T. (1997) Nature 385, 650-653
34. Pluk, H., Dorey, K., and Superti-Furga, G. (2002) Cell 108, 247-259
35. Lougheed, J. C., Chen, R. H., Mak, P., and Stout, T. J. (2004) J. Biol. Chem. 279, 44039-44045
36. Blume-Jensen, P., and Hunter, T. (2001) Nature 411, 355-365
37. Hubbard, S. R., and Till, J. H. (2000) Annu. Rev. Biochem. 69, 373-398
38. Nolen, B., Taylor, S., and Ghosh, G. (2004) Mol. Cell 15, 661-675
39. Greenman, C., Stephens, P., Smith, R., Dalgliesh, G. L., Hunter, C., Bignell, G., Davies, H., Teague, J., Butler, A., Stevens, C., Edkins, S., O'Meara, S., Vastrik, I., Schmidt, E. E., Avis, T., Barthorpe, S., Bhamra, G., Buck, G., Choudhury, B., Clements, J., Cole, J., Dicks, E., Forbes, S., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J., Jenkinson, A., Jones, D., Menzies, A., Mironenko, T., Perry, J., Raine, K., Richardson, D., Shepherd, R., Small, A., Tofts, C., Varian, J., Webb, T., West, S., Widaa, S., Yates, A., Cahill, D. P., Louis, D. N., Goldstraw, P., Nicholson, A. G., Brasseur, F., Looijenga, L., Weber, B. L., Chiew, Y. E., DeFazio, A., Greaves, M. F., Green, A. R., Campbell, P., Birney, E., Easton, D. F., Chenevix-Trench, G., Tan, M. H., Khoo, S. K., Teh, B. T., Yuen, S. T., Leung, S. Y., Wooster, R., Futreal, P. A., and Stratton, M. R. (2007) Nature 446, 153-158
40. Wu, X., Zhao, X., Baylor, L., Kaushal, S., Eisenberg, E., and Greene, L. E. (2001) J. Cell Biol. 155, 291-300
41. Thomas, M., Lu, J. J., Ge, Q., Zhang, C., Chen, J., and Klibanov, A. M. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 5679-5684
42. Yokoyama, N., and Miller, W. T. (2006) Methods Enzymol. 406, 250-260
43. Manning, G., Whyte, D. B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002) Science 298, 1912-1934
44. Zhang, X., Gureasko, J., Shen, K., Cole, P. A., and Kuriyan, J. (2006) Cell 125, 1137-1149
45. Anastasi, S., Baietti, M. F., Frosi, Y., Alemà, S., and Segatto, O. (2007) Oncogene 26, 7833-7846
46. Stapleton, D., Balan, I., Pawson, T., and Sicheri, F. (1999) Nat. Struct. Biol. 6, 44-49
47. Thanos, C. D., Goodwill, K. E., and Bowie, J. U. (1999) Science 283, 833-836
48. Harada, B. T., Knight, M. J., Imai, S., Qiao, F., Ramachander, R., Sawaya, M. R., Gingery, M., Sakane, F., and Bowie, J. U. (2008) Structure 16, 380-387
49. Kim, C. A., Phillips, M. L., Kim, W., Gingery, M., Tran, H. H., Robinson, M. A., Faham, S., and Bowie, J. U. (2001) EMBO J. 20, 4173-4182
50. Kim, C. A., Gingery, M., Pilpa, R. M., and Bowie, J. U. (2002) Nat. Struct. Biol. 9, 453-457
51. Xu, W., Doshi, A., Lei, M., Eck, M. J., and Harrison, S. C. (1999) Mol. Cell 3, 629-638
52. Nagar, B., Hantschel, O., Young, M. A., Scheffzek, K., Veach, D., Bornmann, W., Clarkson, B., Superti-Furga, G., and Kuriyan, J. (2003) Cell 112, 859-871
53. Lietha, D., Cai, X., Ceccarelli, D. F., Li, Y., Schaller, M. D., and Eck, M. J. (2007) Cell 129, 1177-1187