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Volumn 95, Issue 9, 2005, Pages 1320-1326

The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: Modifications to the androgen receptor

Author keywords

Androgen receptor; Hormone resistance; MAP kinase; PI3K and PKC

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; GONADORELIN AGONIST; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; TESTOSTERONE;

EID: 20444403792     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2005.05526.x     Document Type: Review
Times cited : (114)

References (34)
  • 2
    • 0036820698 scopus 로고    scopus 로고
    • Looking to the future. Advances in the management of hormone-refractory prostate cancer
    • Trachtenberg J, Blackledge G. Looking to the future. Advances in the management of hormone-refractory prostate cancer. Eur Urol Suppl 2002; 1: 44-53
    • (2002) Eur Urol Suppl , vol.1 , pp. 44-53
    • Trachtenberg, J.1    Blackledge, G.2
  • 3
    • 1242329061 scopus 로고    scopus 로고
    • Antiandrogen monotherapy. Recommendations for the treatment of prostate cancer
    • Sciarra A, Cardi A, Di Silverio F. Antiandrogen monotherapy. Recommendations for the treatment of prostate cancer. Urologia Intis 2004; 72: 91-8
    • (2004) Urologia Intis , vol.72 , pp. 91-98
    • Sciarra, A.1    Cardi, A.2    Di Silverio, F.3
  • 4
    • 0037599536 scopus 로고    scopus 로고
    • Androgen receptor involvement in the progression of prostate cancer
    • Suzuki H, Ueda T, Ichikawa T, Ito H. Androgen receptor involvement in the progression of prostate cancer. Endocrine-Related Cancer 2003; 10: 209-16
    • (2003) Endocrine-Related Cancer , vol.10 , pp. 209-216
    • Suzuki, H.1    Ueda, T.2    Ichikawa, T.3    Ito, H.4
  • 5
    • 0042329769 scopus 로고    scopus 로고
    • Recent advances in androgen receptor action
    • Lee HJ, Chang C. Recent advances in androgen receptor action. Cellular Mol Life Sci 2003; 60: 1613-22
    • (2003) Cellular Mol Life Sci , vol.60 , pp. 1613-1622
    • Lee, H.J.1    Chang, C.2
  • 6
    • 0034811237 scopus 로고    scopus 로고
    • Identification of a novel phosphorylation site in human androgen receptor by mass spectrometry
    • Zhu Z, Becklin RR, Desiderio DM, Dalton JT. Identification of a novel phosphorylation site in human androgen receptor by mass spectrometry. Biochem Biophys Res Comms 2001 ; 284: 836-44
    • (2001) Biochem Biophys Res Comms , vol.284 , pp. 836-844
    • Zhu, Z.1    Becklin, R.R.2    Desiderio, D.M.3    Dalton, J.T.4
  • 8
    • 0034566055 scopus 로고    scopus 로고
    • Expression and function of androgen receptor in carcinoma of the prostate
    • Culig Z, Hobisch A, Bartsch G, Klocker H. Expression and function of androgen receptor in carcinoma of the prostate. Microscopy Res Technique 2000; 51: 447-55
    • (2000) Microscopy Res Technique , vol.51 , pp. 447-455
    • Culig, Z.1    Hobisch, A.2    Bartsch, G.3    Klocker, H.4
  • 9
    • 0031946389 scopus 로고    scopus 로고
    • Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
    • Culig Z, Hobisch A, Hittmair A et al. Expression, structure, and function of androgen receptor in advanced prostatic carcinoma. Prostate 1998; 35: 63-70
    • (1998) Prostate , vol.35 , pp. 63-70
    • Culig, Z.1    Hobisch, A.2    Hittmair, A.3
  • 10
    • 0042130389 scopus 로고    scopus 로고
    • Androgen receptor mutations in androgen-in dependent prostate cancer: Cancer and Leukemia Group B Study 9663
    • Taplin ME, Rajeshkumar B, Halabi S et al. Androgen receptor mutations in androgen-in dependent prostate cancer: Cancer and Leukemia Group B Study 9663. J Clin Oncol 2003; 21: 2673-8
    • (2003) J Clin Oncol , vol.21 , pp. 2673-2678
    • Taplin, M.E.1    Rajeshkumar, B.2    Halabi, S.3
  • 11
    • 0033152164 scopus 로고    scopus 로고
    • Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
    • Taplin ME, Bubley GJ, Ko YJ et al. Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 1999; 59: 2511-5
    • (1999) Cancer Res , vol.59 , pp. 2511-2515
    • Taplin, M.E.1    Bubley, G.J.2    Ko, Y.J.3
  • 12
    • 0347364754 scopus 로고    scopus 로고
    • Androgen receptor mutations in high-grade prostate cancer before hormonal therapy
    • Thompson J, Hyytinen ER, Haapala K et al. Androgen receptor mutations in high-grade prostate cancer before hormonal therapy. Laboratory Invest 2003; 83: 1709-13
    • (2003) Laboratory Invest , vol.83 , pp. 1709-1713
    • Thompson, J.1    Hyytinen, E.R.2    Haapala, K.3
  • 13
    • 0034895975 scopus 로고    scopus 로고
    • Co-location of androgen receptor gene mutations in prostate cancer
    • Buchanan G, Greenberg NM, Scher HI et al. Co-location of androgen receptor gene mutations in prostate cancer. Clin Cancer Res 2001; 7: 1273-81
    • (2001) Clin Cancer Res , vol.7 , pp. 1273-1281
    • Buchanan, G.1    Greenberg, N.M.2    Scher, H.I.3
  • 14
  • 15
    • 0033822710 scopus 로고    scopus 로고
    • CL1-GFP. An androgen independent metastatic tumor model for prostate cancer
    • Patel BJ, Pantuck AJ, Zisman A et al. CL1-GFP. an androgen independent metastatic tumor model for prostate cancer. J Urol 2000; 164: 1420-5
    • (2000) J Urol , vol.164 , pp. 1420-1425
    • Patel, B.J.1    Pantuck, A.J.2    Zisman, A.3
  • 16
    • 0037119458 scopus 로고    scopus 로고
    • Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance
    • Thakkar H, Chen XF, Tyan F et al. Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance. J Biol Chem 2002; 277: 30408
    • (2002) J Biol Chem , vol.277 , pp. 30408
    • Thakkar, H.1    Chen, X.F.2    Tyan, F.3
  • 17
    • 0034652723 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Marcelli M, Ittmann M, Mariani S et al. Androgen receptor mutations in prostate cancer. Cancer Res 2000; 60: 944-9
    • (2000) Cancer Res , vol.60 , pp. 944-949
    • Marcelli, M.1    Ittmann, M.2    Mariani, S.3
  • 18
    • 0032850869 scopus 로고    scopus 로고
    • Androgen receptor gene amplification increases tissue PSA protein expression in hormone-refractory prostate carcinoma
    • Koivisto PA, Helin HJ. Androgen receptor gene amplification increases tissue PSA protein expression in hormone-refractory prostate carcinoma. J Pathol 1999; 189: 219-23
    • (1999) J Pathol , vol.189 , pp. 219-223
    • Koivisto, P.A.1    Helin, H.J.2
  • 19
    • 0042978480 scopus 로고    scopus 로고
    • Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
    • Edwards J, Krishna NS, Bartlett JMS. Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer 2003; 89: 552-6
    • (2003) Br J Cancer , vol.89 , pp. 552-556
    • Edwards, J.1    Krishna, N.S.2    Bartlett, J.M.S.3
  • 20
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen CD, Welsbie DS, Tran C et al. Molecular determinants of resistance to antiandrogen therapy. Nature Med 2004; 10: 33-9
    • (2004) Nature Med , vol.10 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 21
    • 0032539993 scopus 로고    scopus 로고
    • Forskolin-induced dephosphorylation of the androgen receptor impairs ligand binding
    • Blok LJ, de Ruiter PE, Brinkmann AO. Forskolin-induced dephosphorylation of the androgen receptor impairs ligand binding. Biochemistry 1998; 37: 3850-7
    • (1998) Biochemistry , vol.37 , pp. 3850-3857
    • Blok, L.J.1    De Ruiter, P.E.2    Brinkmann, A.O.3
  • 22
    • 0037399647 scopus 로고    scopus 로고
    • Nuclear receptors. Integration of multiple signalling pathways through phosphorylation
    • Rochette-Egly C. Nuclear receptors. Integration of multiple signalling pathways through phosphorylation. Cellular Signalling 2003; 15: 355-66
    • (2003) Cellular Signalling , vol.15 , pp. 355-366
    • Rochette-Egly, C.1
  • 23
    • 0035912833 scopus 로고    scopus 로고
    • Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
    • Lin HK, Yeh SY, Kang HY, Chang CS. Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc Natl Acad Sci USA 2001; 98: 7200-5
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7200-7205
    • Lin, H.K.1    Yeh, S.Y.2    Kang, H.Y.3    Chang, C.S.4
  • 24
    • 0037404983 scopus 로고    scopus 로고
    • Differential expression and/or activation of P38MAPK, Erk1/2, and Jnk during the initiation and progression of prostate cancer
    • Uzgare AR, Kaplan PJ, Greenberg NM. Differential expression and/or activation of P38MAPK, Erk1/2, and Jnk during the initiation and progression of prostate cancer. Prostate 2003; 55: 128-39
    • (2003) Prostate , vol.55 , pp. 128-139
    • Uzgare, A.R.1    Kaplan, P.J.2    Greenberg, N.M.3
  • 25
    • 0037447330 scopus 로고    scopus 로고
    • Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells
    • Bakin RE, Gioeli D, Sikes RA, Bissonette EA, Weber MJ. Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. Cancer Res 2003; 63: 1981-9
    • (2003) Cancer Res , vol.63 , pp. 1981-1989
    • Bakin, R.E.1    Gioeli, D.2    Sikes, R.A.3    Bissonette, E.A.4    Weber, M.J.5
  • 26
    • 0347696003 scopus 로고    scopus 로고
    • Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers
    • Lin HK, Hu YC, Yang L et al. Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J Biol Chem 2003; 278: 50902-7
    • (2003) J Biol Chem , vol.278 , pp. 50902-50907
    • Lin, H.K.1    Hu, Y.C.2    Yang, L.3
  • 27
    • 0142117190 scopus 로고    scopus 로고
    • Increase of AKT/PKB expression correlates with Gleason pattern in human prostate cancer
    • Liao YD, Grobholz R, Abel U et al. Increase of AKT/PKB expression correlates with Gleason pattern in human prostate cancer. Int J Cancer 2003; 107: 676-80
    • (2003) Int J Cancer , vol.107 , pp. 676-680
    • Liao, Y.D.1    Grobholz, R.2    Abel, U.3
  • 29
    • 0141927222 scopus 로고    scopus 로고
    • Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer
    • Gao N, Zhang Z, Jiang BH, Shi XL. Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Comms 2003; 310: 1124-32
    • (2003) Biochem Biophys Res Comms , vol.310 , pp. 1124-1132
    • Gao, N.1    Zhang, Z.2    Jiang, B.H.3    Shi, X.L.4
  • 30
    • 0034749615 scopus 로고    scopus 로고
    • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
    • Murillo H, Huang HJ, Schmidt U, Smith DI, Tindall DJ. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 2001; 142: 4795-805
    • (2001) Endocrinology , vol.142 , pp. 4795-4805
    • Murillo, H.1    Huang, H.J.2    Schmidt, U.3    Smith, D.I.4    Tindall, D.J.5
  • 31
    • 0033152165 scopus 로고    scopus 로고
    • Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
    • Davies MA, Koul D, Dhesi H et al. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res 1999; 59: 2551-6
    • (1999) Cancer Res , vol.59 , pp. 2551-2556
    • Davies, M.A.1    Koul, D.2    Dhesi, H.3
  • 32
    • 0036554734 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
    • Malik SN, Brattain M, Ghosh PM et al. Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 2002; 8: 1168-71
    • (2002) Clin Cancer Res , vol.8 , pp. 1168-1171
    • Malik, S.N.1    Brattain, M.2    Ghosh, P.M.3
  • 33
    • 2542534542 scopus 로고    scopus 로고
    • Protein kinase C-alpha in prostate cancer
    • Iahn M, Sundel K, Gleave M et al. Protein kinase C-alpha in prostate cancer. BJU Int 2004; 93: 1076-81
    • (2004) BJU Int , vol.93 , pp. 1076-1081
    • Iahn, M.1    Sundel, K.2    Gleave, M.3
  • 34
    • 19044380048 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation - Regulation and identification of the phosphorylation sites
    • Gioeli D, Ficarro SB, Kwiek JJ et al. Androgen receptor phosphorylation - Regulation and identification of the phosphorylation sites. J Biol Chem 2002; 277: 29304-14
    • (2002) J Biol Chem , vol.277 , pp. 29304-29314
    • Gioeli, D.1    Ficarro, S.B.2    Kwiek, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.