Partial attenuation of respiratory syncytial virus with a deletion of a small hydrophobic gene is associated with elevated interleukin-1β responses

Journal of Virology

Volumn 89, Issue 17, 2015, Pages 8974-8981

  Russell, Ryan F ^a   McDonald, Jacqueline U ^a   Ivanova, Maria ^a   Zhong, Ziyun ^a   Bukreyev, Alexander ^b,c   Tregoning, John S ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; VIRUS RNA; IL1B PROTEIN, MOUSE; LIVE VACCINE; ONCOPROTEIN; RESPIRATORY SYNCYTIAL VIRUS VACCINE; SMALL HYDROPHOBIC PROTEIN, VIRUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; GENE DELETION; GENETIC ASSOCIATION; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INDUCTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SH GENE; VIRUS GENE; VIRUS INACTIVATION; VIRUS LOAD; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL LINE; EPITHELIUM CELL; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; MACROPHAGE; NEUTROPHIL; VACCINATION; VIROLOGY;

BOS; MUS; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANIMALS; CELL LINE; EPITHELIAL CELLS; FEMALE; GENE DELETION; GENE KNOCKOUT TECHNIQUES; HUMANS; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED BALB C; NEUTROPHILS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS VACCINES; RESPIRATORY SYNCYTIAL VIRUSES; RETROVIRIDAE PROTEINS, ONCOGENIC; VACCINATION; VACCINES, ATTENUATED; VIRAL LOAD;

EID: 84938941825     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01070-15     Document Type: Article

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