The secreted g protein of human respiratory syncytial virus antagonizes antibody-mediated restriction of replication involving macrophages and complement

Journal of Virology

Volumn 86, Issue 19, 2012, Pages 10880-10884

  Bukreyev, Alexander ^a,b   Yang, Lijuan ^a   Collins, Peter L ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENT; FC RECEPTOR; GLYCOPROTEIN F; PROTEIN G; RESPIRATORY SYNCYTIAL VIRUS ANTIBODY; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL FUNCTION; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NEUTROPHIL; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PNEUMOVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRAL CLEARANCE; VIRUS GENE; VIRUS NEUTRALIZATION; VIRUS REPLICATION;

ANIMALS; ANTIBODIES; ANTIGENS; CODON; COMPLEMENT SYSTEM PROTEINS; GLYCOPROTEINS; HUMANS; LEUKOCYTES; LUNG; MACROPHAGES; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; NEUTROPHILS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRAL ENVELOPE PROTEINS;

HUMAN RESPIRATORY SYNCYTIAL VIRUS; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

EID: 84869056804     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01162-12     Document Type: Article

References (19)

1. Bukreyev A, Belyakov IM, Berzofsky JA, Murphy BR, Collins PL. 2001. Granulocyte-macrophage colony-stimulating factor expressed by recom-binant respiratory syncytial virus attenuates viral replication and increases the level of pulmonary antigen-presenting cells. J. Virol. 75:12128-12140.
2. Bukreyev A, et al. 2008. The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of rep-lication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes. J. Virol. 82:12191-12204.
3. Collins PL, Crowe JEJ. 2007. Respiratory syncytial virus and metapneu- movirus, p 1601-1646. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5 ed, vol 2. Lip-pincott-Raven Publishers, Philadelphia, PA.
4. Hall CB, Kopelman AE, Douglas RG, Jr, Geiman JM, Meagher MP. 1979. Neonatal respiratory syncytial virus infection. N. Engl. J. Med. 300: 393-396.
5. Hall CB, Walsh EE, Long CE, Schnabel KC. 1991. Immunity to and frequency of reinfection with respiratory syncytial virus. J. Infect. Dis. 163:693-698.
6. Henderson FW, Collier AM, Clyde WA, Jr, Denny FW. 1979. Respira- tory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children. N. Engl. J. Med. 300:530-534.
7. Hendricks DA, Baradaran K, McIntosh K, Patterson JL. 1987. Appear-ance of a soluble form of the G protein of respiratory syncytial virus in fluids of infected cells. J. Gen. Virol. 68(Pt 6):1705-1714.
8. Kumagai Y, et al. 2007. Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses. Immunity 27: 240-252.
9. Lagasse E, Weissman IL. 1996. Flow cytometric identification of murine neutrophils and monocytes. J. Immunol. Methods 197:139-150.
10. Nénan S, et al. 2008. Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways. Eur. J. Pharmacol. 579:374-381.
11. Ochsenbein AF, et al. 1999. Control of early viral and bacterial distribu-tion and disease by natural antibodies. Science 286:2156-2159.
12. Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM. 2008. H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog. 4:e1000115.
13. Pribul PK, et al. 2008. Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development. J. Virol. 82:4441-4448.
14. Shiratsuchi Y, et al. 2007. Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production. J. Leukoc. Biol. 81:412-420.
15. Spörri R, Joller N, Hilbi H, Oxenius A. 2008. A novel role for neutrophils as critical activators of NK cells. J. Immunol. 181:7121-7130.
16. Teng MN, Whitehead SS, Collins PL. 2001. Contribution of the respi- ratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivo. Virology 289:283-296.
17. Van den Berg CW, Aerts PC, Van Dijk H. 1991. In vivo anti-complementary activities of the cobra venom factors from Naja naja and Naja haje. J. Immunol. Methods 136:287-294.
18. van Rooijen N, Sanders A, van den Berg TK. 1996. Apoptosis of mac-rophages induced by liposome-mediated intracellular delivery of clodro- nate and propamidine. J. Immunol. Methods 193:93-99.
19. Wright PF, et al. 2007. The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenu-ated, respiratory syncytial virus vaccines. Vaccine 25:7372-7378.