Recombinant bovine respiratory syncytial virus with deletions of the G or SH genes: G and F proteins binds heparin

Journal of General Virology

Volumn 82, Issue 3, 2001, Pages 631-640

  Kargel, A ^a   Schmidt, U ^a   Buchholz, U J ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; HEPARIN; UNCLASSIFIED DRUG; VIRUS ATTACHMENT GLYCOPROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN; VIRUS SMALL HYDROPHOBIC PROTEIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; CELL CULTURE; CONTROLLED STUDY; DELETION MUTANT; GENE DELETION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS ADSORPTION; VIRUS GENE; VIRUS MORPHOGENESIS; VIRUS RECOMBINANT;

ANIMALIA; BOVINAE; BOVINE RESPIRATORY SYNCYTIAL VIRUS; DNA VIRUSES; RESPIRATORY SYNCYTIAL VIRUS; RNA VIRUSES; SYNCYTIAL VIRUS;

EID: 0035109550     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-3-631     Document Type: Article

References (47)

1. Expression of the ORF-2 protein of the human respiratory syncytial virus M2 gene is initiated by a ribosomal termination-dependent reinitiation mechanism
2. The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription
3. Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter
4. Chimeric bovine respiratory syncytial virus with glycoprotein gene substitutions from human respiratory syncytial virus (HRSV): Effects on host range and evaluation as a live-attenuated HRSV vaccine
5. Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse
6. Post-translational processing and oligomerization of the fusion glycoprotein of human respiratory syncytial virus
7. Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virus
8. Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5′ proximal open reading frame of the M2 mRNA in gene capability for vaccine development
9. Transcription elongation factor of respiratory syncytial virus, a non-segmented negative-strand RNA virus
10. Respiratory syncytial virus
11. Role of the M2-1 transcription antitermination protein of respiratory syncytial virus in sequential transcription
12. Identification of a linear heparin binding domain for human respiratory syncytial virus attachment glycoprotein G
13. The fusion glycoprotein of human respiratory syncytial virus facilitates virus attachment and infectivity via an interaction with cellular heparan sulfate
14. Antigenic heterogeneity of the attachment protein of bovine respiratory syncytial virus
15. Marked differences in the antigenic structure of human respiratory syncytial virus F and G glycoproteins
16. The product of the respiratory syncytial virus M2 gene ORF1 enhances readthrough of intergenic junctions during viral transcription
17. The paramyxovirus SV5 small hydrophobic (SH) protein is not essential for virus growth in tissue culture cells
18. Analysis of respiratory syncytial virus F, G, and SH proteins in cell fusion
19. Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2-2) has altered growth characteristics and is attenuated in rodents
20. The G glycoprotein of human respiratory syncytial viruses of subgroups A and B: Extensive sequence divergence between antigenically related proteins
21. Infectivity of a pseudorabies virus mutant lacking attachment glycoproteins C and D
22. Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: Clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant
23. Modulation of cell surface heparan sulfate structure by growth of cells in the presence of chlorate
24. Heparin-dependent attachment of respiratory syncytial virus (RSV) to host cells
25. Effects of mutations in the gene-start and gene-end sequence motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus
26. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
27. Proposed three-dimensional model for the attachment protein G of respiratory syncytial virus
28. Nucleotide sequence analysis and expression from recombinant vectors demonstrate that the attachment protein G of bovine respiratory syncytial virus is distinct from that of human respiratory syncytial virus
29. Demonstration that glycoprotein G is the attachment protein of respiratory syncytial virus
30. Sequence variability of the glycoprotein gene of bovine respiratory syncytial virus
31. The 1A protein of respiratory syncytial virus is an integral membrane protein present as multiple, structurally distinct species
32. Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: Comparison of the individual contributions of the F and G glycoproteins to host immunity
33. Analysis of bovine respiratory syncytial virus envelope glycoproteins in cell fusion
34. Membrane permeability changes induced in Escherichia coli by the SH protein of human respiratory syncytial virus
35. Microbial adherence to and invasion through proteoglycans
36. Nucleotide sequence analysis of a matrix and small hydrophobic protein dicistronic mRNA of bovine respiratory syncytial virus demonstrates extensive sequence divergence of the small hydrophobic protein from that syncytial virus
37. Respiratory syncytial virus envelope glycoprotein (G) has a novel structure
38. The mumps virus SH protein is a membrane protein and not essential for virus growth
39. Monoclonal antibodies protect against respiratory syncytial virus infection in mice
40. Identification of the respiratory syncytial virus proteins required for formation and passage of helper-dependent infectious particles
41. Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein
42. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
43. Respiratory syncytial virus infections in human beings and in cattle
44. Monoclonal antibodies to respiratory syncytial virus proteins: Identification of the fusion protein
45. Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein
46. Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees
47. Gene junction sequences of bovine respiratory syncytial virus