-
1
-
-
0022481133
-
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
-
Sen, R. & Baltimore, D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell. 46, 705-716 (1986
-
(1986)
Cell
, vol.46
, pp. 705-716
-
-
Sen, R.1
Baltimore, D.2
-
2
-
-
54949147176
-
New regulators of nf-kappab in inflammation
-
Ghosh, S. & Hayden, M. S. New regulators of NF-kappaB in inflammation. Nat Rev Immunol 8, 837-848 (2008
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
3
-
-
33750443289
-
Ikappab kinase complexes: Gateways to nf-kappab activation and transcription
-
Scheidereit, C. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene. 25, 6685-6705 (2006
-
(2006)
Oncogene
, vol.25
, pp. 6685-6705
-
-
Scheidereit, C.1
-
4
-
-
84862761186
-
Diverse ubiquitin signaling in nf-kappab activation
-
Iwai, K. Diverse ubiquitin signaling in NF-kappaB activation. Trends Cell Biol. 22, 355-364 (2012
-
(2012)
Trends Cell Biol
, vol.22
, pp. 355-364
-
-
Iwai, K.1
-
5
-
-
0030004897
-
Site-specific phosphorylation of ikappabalpha by a novel ubiquitination-dependent protein kinase activity
-
Chen, Z. J., Parent, L. & Maniatis, T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell. 84, 853-862 (1996
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
6
-
-
23144449789
-
Ubiquitin signalling in the nf-kappab pathway
-
Chen, Z. J. Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 7, 758-765 (2005
-
(2005)
Nat Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
7
-
-
84894559172
-
Ubiquitin in the immune system
-
Zinngrebe, J., Montinaro, A., Peltzer, N. & Walczak, H. Ubiquitin in the immune system. Embo Rep. 15, 28-45 (2014
-
(2014)
Embo Rep
, vol.15
, pp. 28-45
-
-
Zinngrebe, J.1
Montinaro, A.2
Peltzer, N.3
Walczak, H.4
-
8
-
-
0033106149
-
A ubiquitin ligase complex essential for the nf-kappab wnt/wingless and hedgehog signaling pathways
-
Maniatis, T. A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev. 13, 505-510 (1999
-
(1999)
Genes Dev
, vol.13
, pp. 505-510
-
-
Maniatis, T.1
-
9
-
-
0029874138
-
The nf-kappa b and i kappa b proteins: New discoveries and insights
-
Baldwin, A. J. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 14, 649-683 (1996
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin, A.J.1
-
10
-
-
67650724069
-
Regulation and function of nf-kappab transcription factors in the immune system
-
Vallabhapurapu, S. & Karin, M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol. 27, 693-733 (2009
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
11
-
-
78650300883
-
C-iap1 and ubch5 promote k11-linked polyubiquitination of rip1 in TNF signalling
-
Dynek, J. N., et al. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. EMBO J 29, 4198-4209 (2010
-
(2010)
EMBO J
, vol.29
, pp. 4198-4209
-
-
Dynek, J.N.1
-
12
-
-
0035913278
-
Tak1 is a ubiquitin-dependent kinase of mkk and ikk
-
Wang, C., et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412, 346-351 (2001
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
-
13
-
-
82755190610
-
Tripartite motif 8 (trim8) modulates tnfalpha- and il-1beta-Triggered nf-kappab activation by targeting tak1 for k63-linked polyubiquitination
-
Li, Q., et al. Tripartite motif 8 (TRIM8) modulates TNFalpha- And IL-1beta-Triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination. Proc Natl Acad Sci USA. 108, 19341-19346 (2011
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19341-19346
-
-
Li, Q.1
-
14
-
-
77957677615
-
Polyubiquitin conjugation to nemo by triparite motif protein 23 (trim23) is critical in antiviral defense
-
Arimoto, K., et al. Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense. Proc Natl Acad Sci USA. 107, 15856-15861 (2010
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15856-15861
-
-
Arimoto, K.1
-
15
-
-
84903556575
-
Rhbdd3 controls autoimmunity by suppressing the production of il-6 by dendritic cells via k27-linked ubiquitination of the regulator nemo
-
Liu, J., et al. Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. Nat Immunol. 15, 612-622 (2014
-
(2014)
Nat Immunol
, vol.15
, pp. 612-622
-
-
Liu, J.1
-
16
-
-
59649103156
-
Involvement of linear polyubiquitylation of nemo in nf-kappab activation
-
Tokunaga, F., et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol. 11, 123-132 (2009
-
(2009)
Nat Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
-
17
-
-
69949093459
-
Direct activation of protein kinases by unanchored polyubiquitin chains
-
Xia, Z. P., et al. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature. 461, 114-119 (2009
-
(2009)
Nature
, vol.461
, pp. 114-119
-
-
Xia, Z.P.1
-
18
-
-
84875236362
-
Regulation of nf-kappab by ubiquitination
-
Chen, J. & Chen, Z. J. Regulation of NF-kappaB by ubiquitination. Curr Opin Immunol. 25, 4-12 (2013
-
(2013)
Curr Opin Immunol
, vol.25
, pp. 4-12
-
-
Chen, J.1
Chen, Z.J.2
-
19
-
-
78650915537
-
Deubiquitinases in the regulation of nf-kappab signaling
-
Harhaj, E. W. & Dixit, V. M. Deubiquitinases in the regulation of NF-kappaB signaling. Cell Res. 21, 22-39 (2011
-
(2011)
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
20
-
-
84858725584
-
Regulation of nf-kappab by deubiquitinases
-
Harhaj, E. W. & Dixit, V. M. Regulation of NF-kappaB by deubiquitinases. Immunol Rev. 246, 107-124 (2012
-
(2012)
Immunol Rev
, vol.246
, pp. 107-124
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
21
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of a20 downregulate nf-kappab signalling
-
Wertz, I. E., et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature. 430, 694-699 (2004
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
-
22
-
-
80052691620
-
Usp4 targets tak1 to downregulate tnfalpha-induced nf-kappab activation
-
Fan, Y. H., et al. USP4 targets TAK1 to downregulate TNFalpha-induced NF-kappaB activation. Cell Death Differ. 18, 1547-1560 (2011
-
(2011)
Cell Death Differ
, vol.18
, pp. 1547-1560
-
-
Fan, Y.H.1
-
23
-
-
0035906250
-
Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol rash
-
Kang, D., Jiang, H., Wu, Q., Pestka, S. & Fisher, P. B. Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH. Gene. 267, 233-242 (2001
-
(2001)
Gene
, vol.267
, pp. 233-242
-
-
Kang, D.1
Jiang, H.2
Wu, Q.3
Pestka, S.4
Fisher, P.B.5
-
24
-
-
0037155882
-
Ubp43 (usp18) specifically removes isg15 from conjugated proteins
-
Malakhov, M. P., Malakhova, O. A., Kim, K. I., Ritchie, K. J. & Zhang, D. E. UBP43 (USP18) specifically removes ISG15 from conjugated proteins. J Biol Chem. 277, 9976-9981 (2002
-
(2002)
J Biol Chem
, vol.277
, pp. 9976-9981
-
-
Malakhov, M.P.1
Malakhova, O.A.2
Kim, K.I.3
Ritchie, K.J.4
Zhang, D.E.5
-
25
-
-
30644470650
-
Ube1l and protein isgylation are not essential for alpha/beta interferon signaling
-
Kim, K. I., et al. Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling. Mol Cell Biol. 26, 472-479 (2006
-
(2006)
Mol Cell Biol
, vol.26
, pp. 472-479
-
-
Kim, K.I.1
-
26
-
-
33745761009
-
Ubp43 is a novel regulator of interferon signaling independent of its isg15 isopeptidase activity
-
Malakhova, O. A., et al. UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J 25, 2358-2367 (2006
-
(2006)
EMBO J
, vol.25
, pp. 2358-2367
-
-
Malakhova, O.A.1
-
27
-
-
84884234601
-
Usp18 inhibits nf-kappab and nfat activation during th17 differentiation by deubiquitinating the tak1-Tab1 complex
-
Liu, X., et al. USP18 inhibits NF-kappaB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex. J Exp Med. 210, 1575-1590 (2013
-
(2013)
J Exp Med
, vol.210
, pp. 1575-1590
-
-
Liu, X.1
-
28
-
-
0031897632
-
Nf-kappa b and rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh, S., May, M. J. & Kopp, E. B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 16, 225-260 (1998
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
29
-
-
33645703930
-
Sensing of lys 63-linked polyubiquitination by nemo is a key event in nf-kappab activation [corrected
-
Wu, C. J., Conze, D. B., Li, T., Srinivasula, S. M. & Ashwell, J. D. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 8, 398-406 (2006
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
30
-
-
33646066025
-
The ubiquitin binding domain znf ubp recognizes the c-Terminal diglycine motif of unanchored ubiquitin
-
Reyes-Turcu, F. E., et al. The ubiquitin binding domain ZnF UBP recognizes the C-Terminal diglycine motif of unanchored ubiquitin. Cell. 124, 1197-1208 (2006
-
(2006)
Cell
, vol.124
, pp. 1197-1208
-
-
Reyes-Turcu, F.E.1
-
31
-
-
40749139505
-
Interleukin-1 (il-1 induces the lys63-linked polyubiquitination of il-1 receptor-Associated kinase 1 to facilitate nemo binding and the activation of ikappabalpha kinase
-
Windheim, M., Stafford, M., Peggie, M. & Cohen, P. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-Associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Mol Cell Biol. 28, 1783-1791 (2008
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1783-1791
-
-
Windheim, M.1
Stafford, M.2
Peggie, M.3
Cohen, P.4
-
32
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by nemo is important for nf-kappab activation
-
Rahighi, S., et al. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell. 136, 1098-1109 (2009
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
-
33
-
-
35748929941
-
Identification of traf6-dependent nemo polyubiquitination sites through analysis of a new nemo mutation causing incontinentia pigmenti
-
Sebban-Benin, H., et al. Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti. Hum Mol Genet. 16, 2805-2815 (2007
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2805-2815
-
-
Sebban-Benin, H.1
-
34
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell. 140, 805-820 (2010
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
35
-
-
33745298519
-
Nuclear factor-kappab in cancer development and progression
-
Karin, M. Nuclear factor-kappaB in cancer development and progression. Nature. 441, 431-436 (2006
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
36
-
-
77950346282
-
Immunity inflammation, and cancer
-
Grivennikov, S. I., Greten, F. R. & Karin, M. Immunity, inflammation, and cancer. Cell. 140, 883-899 (2010
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
37
-
-
0042467558
-
Cyld is a deubiquitinating enzyme that negatively regulates nf-kappab activation by tnfr family members
-
Trompouki, E., et al. CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature. 424, 793-796 (2003
-
(2003)
Nature
, vol.424
, pp. 793-796
-
-
Trompouki, E.1
-
38
-
-
84867062977
-
A20 inhibits lubac-mediated nf-kappab activation by binding linear polyubiquitin chains via its zinc finger 7
-
Verhelst, K., et al. A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger. 7. EMBO J 31, 3845-3855 (2012
-
(2012)
Embo J
, vol.31
, pp. 3845-3855
-
-
Verhelst, K.1
-
39
-
-
51349108659
-
Negative regulation of cytoplasmic RNA-mediated antiviral signaling
-
Komuro, A., Bamming, D. & Horvath, C. M. Negative regulation of cytoplasmic RNA-mediated antiviral signaling. Cytokine. 43, 350-358 (2008
-
(2008)
Cytokine
, vol.43
, pp. 350-358
-
-
Komuro, A.1
Bamming, D.2
Horvath, C.M.3
-
40
-
-
61649103747
-
Structural basis for recognition of diubiquitins by nemo
-
Lo, Y. C., et al. Structural basis for recognition of diubiquitins by NEMO. Mol Cell. 33, 602-615 (2009
-
(2009)
Mol Cell
, vol.33
, pp. 602-615
-
-
Lo, Y.C.1
-
41
-
-
84884345970
-
Activation of the canonical ikk complex by k63/m1-linked hybrid ubiquitin chains
-
Emmerich, C. H., et al. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proc Natl Acad Sci USA. 110, 15247-15252 (2013
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 15247-15252
-
-
Emmerich, C.H.1
|