Usp18 inhibits NF-κb and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex

Journal of Experimental Medicine

Volumn 210, Issue 8, 2013, Pages 1575-1590

  Liu, Xikui ^a   Li, Hongxiu ^a   Zhong, Bo ^a   Blonska, Marzenna ^a   Gorjestani, Sara ^a,b   Yan, Ming ^d   Tian, Qiang ^c   Zhang, Dong Er ^d   Lin, Xin ^a,b   Dong, Chen ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHAPERONE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MESSENGER RNA; PROTEIN; PROTEIN TAB1; TRANSCRIPTION FACTOR NFAT; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UBIQUITIN SPECIFIC PROTEASE 18; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LYMPHOCYTE DIFFERENTIATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; UBIQUITINATION; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTOIMMUNE DISEASES; CATALYSIS; CELL DIFFERENTIATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOPEPTIDASES; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; INTERLEUKIN-2; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TH17 CELLS; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84884234601     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122327     Document Type: Article

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