Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels

Botanical Review

Volumn 16, Issue 6, 2014, Pages 1344-1357

  Sassene, Philip ^a   Kleberg, Karen ^a   Williams, Hywel D ^b   Bakala N’Goma, Jean Claude ^c   Carrière, Frédéric ^c   Calderone, Marilyn ^d   Jannin, Vincent ^e   Igonin, Annabel ^f   Partheil, Anette ^g   Marchaud, Delphine ^e   Jule, Eduardo ^f   Vertommen, Jan ^f   Maio, Mario ^g   Blundell, Ross ^d   Benameur, Hassan ^f   Porter, Christopher J H ^b   Pouton, Colin W ^b   Müllertz, Anette ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b MONASH UNIVERSITY   (Australia)

^c AIX MARSEILLE UNIVERSITY   (France)

^d SANOFI   (France)

^e GATTEFOSSÉ SAS   (France)

^f CAPSUGEL   (France)

^g MERCK KGAA   (Germany)

Author keywords

danazol; digestion; dispersion; drug precipitation; in vitro digestion; LFCS Consortium; lipid formulation

Indexed keywords

CALCIUM; DANAZOL; FATTY ACID; PANCREATIN; LIPID;

ARTICLE; CALCIUM BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIGESTION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; IN VITRO STUDY; IONIZATION; LIPOLYSIS; PRECIPITATION; STANDARDIZATION; BIOLOGICAL MODEL; CHEMISTRY; DOSE RESPONSE; MEDICINAL CHEMISTRY; METABOLISM; PHYSIOLOGY; SOLUBILITY;

CALCIUM; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DANAZOL; DIGESTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; IN VITRO TECHNIQUES; LIPIDS; LIPOLYSIS; MODELS, BIOLOGICAL; PANCREATIN; SOLUBILITY;

EID: 84938785875     PISSN: 00068101     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-014-9672-x     Document Type: Article

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