An evidence-based review of oral magnesium supplementation in the preventive treatment of migraine

Cephalalgia

Volumn 35, Issue 10, 2015, Pages 912-922

  Teigen, Levi ^a,b   Boes, Christopher J ^a,b  

^a DEPARTMENT OF UROLOGY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Magnesium; migraine; migraine prophylaxis

Indexed keywords

MAGNESIUM;

CLINICAL EFFECTIVENESS; DIET SUPPLEMENTATION; EVIDENCE BASED MEDICINE; FOOD COMPOSITION; HUMAN; INTERVENTION STUDY; LIFESTYLE MODIFICATION; MAGNESIUM INTAKE; MIGRAINE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; MULTICENTER STUDY (TOPIC); NUTRITIONAL STATUS; NUTRITIONAL SUPPORT; OUTCOME ASSESSMENT; PAIN INTENSITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; THERAPY EFFECT; BLOOD; DIETARY SUPPLEMENT; MIGRAINE DISORDERS; ORAL DRUG ADMINISTRATION; PROCEDURES; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; DIETARY SUPPLEMENTS; EVIDENCE-BASED MEDICINE; HUMANS; MAGNESIUM; MIGRAINE DISORDERS; TREATMENT OUTCOME;

EID: 84938780173     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102414564891     Document Type: Review

References (76)

1. Insinga RP, Ng-Mak DS, Hanson ME,. Costs associated with outpatient, emergency room and inpatient care for migraine in the USA. Cephalalgia 2011; 31: 1570-1575.
2. Lipton RB, Bigal ME, Diamond M,. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology 2007; 68: 343-349.
3. Lipton RB, Buse DC, Serrano D,. Examination of unmet treatment needs among persons with episodic migraine: Results of the American Migraine Prevalence and Prevention (AMPP) Study. Headache 2013; 53: 1300-1311.
4. Abrams BM,. Medication overuse headaches. Med Clin North Am 2013; 97: 337-352.
5. Bamford C, Tepper S,. Daily pharmacologic prophylaxis of episodic migraine. Tech Reg Anesth Pain Manag 2009; 13: 20-27.
6. Boska MD, Welch KM, Barker PB,. Contrasts in cortical magnesium, phospholipid and energy metabolism between migraine syndromes. Neurology 2002; 58: 1227-1233.
7. Gallai V, Sarchielli P, Morucci P,. Red blood cell magnesium levels in migraine patients. Cephalalgia 1993; 13 (2): 94-98.
8. Gallai V, Sarchielli P, Morucci P,. Magnesium content of mononuclear blood cells in migraine patients. Headache 1994; 34: 160-165.
9. Lodi R, Iotti S, Cortelli P,. Deficient energy metabolism is associated with low free magnesium in the brains of patients with migraine and cluster headache. Brain Res Bull 2001; 54: 437-441.
10. Mauskop A, Altura BT, Altura BM,. Serum ionized magnesium levels and serum ionized calcium/ionized magnesium ratios in women with menstrual migraine. Headache 2002; 42: 242-248.
11. Mauskop A, Altura BT, Cracco RQ,. Deficiency in serum ionized magnesium but not total magnesium in patients with migraines. Possible role of ICa2+/IMg2+ ratio. Headache 1993; 33: 135-138.
12. Mishima K, Takeshima T, Shimomura T,. Platelet ionized magnesium, cyclic AMP, and cyclic GMP levels in migraine and tension-type headache. Headache 1997; 37: 561-564.
13. Qujeq D, Zandemami M, Ahanger AA,. Evaluation of intracellular magnesium and calcium concentration in patients with migraine. Neurosciences (Riyadh) 2012; 17: 85-86.
14. Samaie A, Asghari N, Ghorbani R,. Blood magnesium levels in migraineurs within and between the headache attacks: A case control study. Pan Afr Med J 2012; 11: 46-46.
15. Sarchielli P, Coata G, Firenze C,. Serum and salivary magnesium levels in migraine and tension-type headache. Results in a group of adult patients. Cephalalgia 1992; 12: 21-27.
16. Schoenen J, Sianard-Gainko J, Lenaerts M,. Blood magnesium levels in migraine. Cephalalgia 1991; 11: 97-99.
17. Smeets MC, Vernooy CB, Souverijn JH,. Intracellular and plasma magnesium in familial hemiplegic migraine and migraine with and without aura. Cephalalgia 1994; 14: 29-32.
18. Talebi M, Savadi-Oskouei D, Farhoudi M,. Relation between serum magnesium level and migraine attacks. Neurosciences (Riyadh) 2011; 16: 320-323.
19. Thomas J, Thomas E, Tomb E,. Serum and erythrocyte magnesium concentrations and migraine. Magnes Res 1992; 5: 127-130.
20. Trauninger A, Pfund Z, Koszegi T,. Oral magnesium load test in patients with migraine. Headache 2002; 42: 114-119.
21. Ilhan A, Uz E, Var A,. Diagnostic role of hair magnesium in migraine patients: Higher than serum magnesium. Trace Elements and Electrolytes 2000; 17: 14-18.
22. Welch KM, Ramadan NM,. Mitochondria, magnesium and migraine. J Neurol Sci 1995; 134: 9-14.
23. Facchinetti F, Sances G, Borella P,. Magnesium prophylaxis of menstrual migraine: Effects on intracellular magnesium. Headache 1991; 31: 298-301.
24. Köseoglu E, Talaslioglu A, Gönül AS,. The effects of magnesium prophylaxis in migraine without aura. Magnes Res 2008; 21: 101-108.
25. Peikert A, Wilimzig C, Kohne-Volland R,. Prophylaxis of migraine with oral magnesium: Results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia 1996; 16: 257-263.
26. Pfaffenrath V, Wessely P, Meyer C,. Magnesium in the prophylaxis of migraine-a double-blind placebo-controlled study. Cephalalgia 1996; 16: 436-440.
27. Ayuk J, Gittoes NJ,. Contemporary view of the clinical relevance of magnesium homeostasis. Ann Clin Biochem 2014; 51: 179-188.
28. Jahnen-Dechent W, Ketteler M,. Magnesium basics. Clin Kidney J 2012; 5: i3-i14.
29. Stipanuk MH, Caudill MA,. Biochemical, physiological, and molecular aspects of human nutrition, 3rd edn. St. Louis, Mo.: Elsevier/Saunders, 2013.
30. Musso CG,. Magnesium metabolism in health and disease. Int Urol Nephrol 2009; 41: 357-362.
31. Saris NE, Mervaala E, Karppanen H,. Magnesium. An update on physiological, clinical and analytical aspects. Clin Chim Acta 2000; 294: 1-26.
32. Volpe SL,. Magnesium in disease prevention and overall health. Adv Nutr 2013; 4: 378S-383S.
33. Marier JR,. Magnesium content of the food supply in the modern-day world. Magnesium 1986; 5: 1-8.
34. Quamme GA,. Recent developments in intestinal magnesium absorption. Curr Opin Gastroenterol 2008; 24: 230-235.
35. Vormann J,. Magnesium: Nutrition and metabolism. Mol Aspects Med 2003; 24: 27-37.
36. Moshfegh A, Goldman J, Ahuja J, et al. What We Eat in America. NHANES 2005-2006: Usual nutrient intakes from food and water compared to 1997 dietary reference intakes for vitamin D, calcium, phosphorus, and magnesium. US Department of Agriculture, Agricultural Research Service, 2009.
37. Calvo MS, Uribarri J,. Public health impact of dietary phosphorus excess on bone and cardiovascular health in the general population. Am J Clin Nutr 2013; 98: 6-15.
38. Seo JW, Park TJ,. Magnesium metabolism. Electrolyte Blood Press 2008; 6: 86-95.
39. Kuipers MT, Thang HD, Arntzenius AB,. Hypomagnesaemia due to use of proton pump inhibitors-a review. Neth J Med 2009; 67: 169-172.
40. Bergman EA, Massey LK, Wise KJ,. Effects of dietary caffeine on renal handling of minerals in adult women. Life Sci 1990; 47: 557-564.
41. Kynast-Gales SA, Massey LK,. Effect of caffeine on circadian excretion of urinary calcium and magnesium. J Am Coll Nutr 1994; 13: 467-472.
42. Mauskop A, Varughese J,. Why all migraine patients should be treated with magnesium. J Neural Transm 2012; 119: 575-579.
43. Arnaud MJ,. Update on the assessment of magnesium status. Br J Nutr 2008; 99 (Suppl 3): S24-S36.
44. Sabatier M, Pont F, Arnaud MJ,. A compartmental model of magnesium metabolism in healthy men based on two stable isotope tracers. Am J Physiol Regul Integr Comp Physiol 2003; 285: R656-R663.
45. Franz KB,. A functional biological marker is needed for diagnosing magnesium deficiency. J Am Coll Nutr 2004; 23: 738S-741S.
46. Taylor FR,. Nutraceuticals and headache: The biological basis. Headache 2011; 51: 484-501.
47. Rothrock JF,. What is migraine? Headache 2008; 48: 331-331.
48. Tepper SJ,. Complementary and alternative treatments for childhood headaches. Curr Pain Headache Rep 2008; 12: 379-383.
49. Bhaskar S, Saeidi K, Borhani P,. Recent progress in migraine pathophysiology: Role of cortical spreading depression and magnetic resonance imaging. Eur J Neurosci 2013; 38: 3540-3551.
50. Eikermann-Haerter K, Ayata C,. Cortical spreading depression and migraine. Curr Neurol Neurosci Rep 2010; 10: 167-173.
51. D'Andrea G, Leon A,. Pathogenesis of migraine: From neurotransmitters to neuromodulators and beyond. Neurol Sci 2010; 31 (Suppl 1): S1-S7.
52. Orr SL, Venkateswaran S,. Nutraceuticals in the prophylaxis of pediatric migraine: Evidence-based review and recommendations. Cephalalgia 2014; 34: 568-583.
53. Ramadan NM, Halvorson H, Vande-Linde A,. Low brain magnesium in migraine. Headache 1989; 29: 416-419.
54. Tarighat Esfanjani A, Mahdavi R, Ebrahimi Mameghani M,. The effects of magnesium, L-carnitine, and concurrent magnesium-L-carnitine supplementation in migraine prophylaxis. Biol Trace Elem Res 2012; 150: 42-48.
55. Tfelt-Hansen P, Pascual J, Ramadan N, et al. Guidelines for controlled trials of drugs in migraine: Third edition. A guide for investigators. Cephalalgia 2012; 32: 6-38.
56. Bigal ME, Bordini CA, Tepper SJ,. Intravenous magnesium sulphate in the acute treatment of migraine without aura and migraine with aura. A randomized, double-blind, placebo-controlled study. Cephalalgia 2002; 22: 345-353.
57. Cete Y, Dora B, Ertan C,. A randomized prospective placebo-controlled study of intravenous magnesium sulphate vs. metoclopramide in the management of acute migraine attacks in the emergency department. Cephalalgia 2005; 25: 199-204.
58. Corbo J, Esses D, Bijur PE,. Randomized clinical trial of intravenous magnesium sulfate as an adjunctive medication for emergency department treatment of migraine headache. Ann Emerg Med 2001; 38: 621-627.
59. Demirkaya S, Vural O, Dora B,. Efficacy of intravenous magnesium sulfate in the treatment of acute migraine attacks. Headache 2001; 41: 171-177.
60. Mauskop A, Altura BT, Cracco RQ,. Intravenous magnesium sulfate relieves cluster headaches in patients with low serum ionized magnesium levels. Headache 1995; 35: 597-600.
61. Mauskop A, Altura BT, Cracco RQ,. Intravenous magnesium sulfate rapidly alleviates headaches of various types. Headache 1996; 36: 154-160.
62. Ranade VV, Somberg JC,. Bioavailability and pharmacokinetics of magnesium after administration of magnesium salts to humans. Am J Ther 2001; 8: 345-357.
63. Silberstein SD, Holland S, Freitag F,. Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012; 78: 1337-1345.
64. Evers S, Afra J, Frese A,. EFNS guideline on the drug treatment of migraine-revised report of an EFNS task force. Eur J Neurol 2009; 16: 968-981.
65. Holland S, Silberstein SD, Freitag F,. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012; 78: 1346-1353.
66. Pringsheim T, Davenport W, Mackie G,. Canadian Headache Society guideline for migraine prophylaxis. Can J Neurol Sci 2012; 39: S1-S59.
67. Champagne CM,. Magnesium in hypertension, cardiovascular disease, metabolic syndrome, and other conditions: A review. Nutr Clin Pract 2008; 23: 142-151.
68. Ford ES, Li C, McGuire LC,. Intake of dietary magnesium and the prevalence of the metabolic syndrome among U.S. adults. Obesity (Silver Spring) 2007; 15: 1139-1146.
69. He K, Song Y, Belin RJ,. Magnesium intake and the metabolic syndrome: Epidemiologic evidence to date. J Cardiometab Syndr 2006; 1: 351-355.
70. McKeown NM, Jacques PF, Zhang XL,. Dietary magnesium intake is related to metabolic syndrome in older Americans. Eur J Nutr 2008; 47: 210-216.
71. Dibaba DT, Xun P, Fly AD,. Dietary magnesium intake and risk of metabolic syndrome: A meta-analysis. Diabet Med 2014; 31: 1301-1309.
72. Esmaillzadeh A, Kimiagar M, Mehrabi Y,. Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. Am J Clin Nutr 2006; 84: 1489-1497.
73. Giacco R, Della Pepa G, Luongo D,. Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials. Nutr Metab Cardiovasc Dis 2011; 21: 901-908.
74. Ibarrola-Jurado N, Bulló M, Guasch-Ferré M,. Cross-sectional assessment of nut consumption and obesity, metabolic syndrome and other cardiometabolic risk factors: The PREDIMED study. PLoS One 2013; 8: e57367-e57367.
75. Jarvandi S, Gougeon R, Bader A,. Differences in food intake among obese and nonobese women and men with type 2 diabetes. J Am Coll Nutr 2011; 30: 225-232.
76. Koh-Banerjee P, Franz M, Sampson L,. Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men. Am J Clin Nutr 2004; 80: 1237-1245.