Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Cancer Discovery

Volumn 5, Issue 8, 2015, Pages 821-832

  Murugaesu, Nirupa ^a   Wilson, Gareth A ^a,b   Birkbak, Nicolai J ^a,b   Watkins, Thomas B K ^b   McGranahan, Nicholas ^a,b   Kumar, Sacheen ^c   Abbassi Ghadi, Nima ^c   Salm, Max ^b   Mitter, Richard ^b   Horswell, Stuart ^b   Rowan, Andrew ^b   Phillimore, Benjamin ^b   Biggs, Jennifer ^b   Begum, Sharmin ^b   Matthews, Nik ^b   Hochhauser, Daniel ^a   Hanna, George B ^c   Swanton, Charles ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLATINUM; ANTINEOPLASTIC AGENT;

ADJUVANT CHEMOTHERAPY; ARTICLE; ASSESSMENT OF HUMANS; CELL TRACKING; CHROMOSOMAL INSTABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DISEASE COURSE; ESOPHAGEAL ADENOCARCINOMA; EVOLUTION; GENE AMPLIFICATION; GENE DUPLICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; PHYLOGENETIC TREE CONSTRUCTION METHOD; TREATMENT RESPONSE; TUMOR REGRESSION; TUMOR REGRESSION SCORE; ADENOCARCINOMA; BIOLOGY; CLONAL EVOLUTION; ESOPHAGEAL NEOPLASMS; EXOME; GENETIC VARIATION; GENETICS; GENOMIC INSTABILITY; GENOMICS; HUMAN GENOME; MOLECULAR EVOLUTION; MUTATION; NEOADJUVANT THERAPY; PATHOLOGY; PROCEDURES;

ADENOCARCINOMA; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CLONAL EVOLUTION; COMPUTATIONAL BIOLOGY; DNA COPY NUMBER VARIATIONS; ESOPHAGEAL NEOPLASMS; EVOLUTION, MOLECULAR; EXOME; GENE AMPLIFICATION; GENETIC VARIATION; GENOME, HUMAN; GENOMIC INSTABILITY; GENOMICS; HUMANS; MUTATION; NEOADJUVANT THERAPY; PLATINUM;

EID: 84938770152     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-15-0412     Document Type: Article

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