-
1
-
-
59149085501
-
The global burden of hepatitis c
-
Lavanchy, D. The global burden of hepatitis C. Liver Int. 29, 74-81, doi: 10.1111/j.1478-3231.2008.01934.x (2009
-
(2009)
Liver Int
, vol.29
, pp. 74-81
-
-
Lavanchy, D.1
-
2
-
-
84857144025
-
The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007
-
Ly, K. N., et al. The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007. Ann. Intern. Med. 156, 271-278, doi: 10.7326/0003-4819-156-4-201202210-00004 (2012
-
(2012)
Ann. Intern. Med
, vol.156
, pp. 271-278
-
-
Ly, K.N.1
-
3
-
-
23944506014
-
Global epidemiology of hepatitis C virus infection
-
Shepard, C. W., Finelli, L. & Alter, M. Global epidemiology of hepatitis C virus infection. Lancet Infect. Dis. 5, 558-567, doi: 10.1016/s1473-3099(05)70216-4 (2005
-
(2005)
Lancet Infect. Dis
, vol.5
, pp. 558-567
-
-
Shepard, C.W.1
Finelli, L.2
Alter, M.3
-
4
-
-
84921060015
-
Global distribution and prevalence of hepatitis c virus genotypes
-
Messina, J. P., et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology 61, 77-87, doi: 10.1002/hep.27259 (2015
-
(2015)
Hepatology
, vol.61
, pp. 77-87
-
-
Messina, J.P.1
-
5
-
-
84901586232
-
Hepatitis c treatment: An incipient therapeutic revolution
-
deLemos, A. S. & Chung, R. T. Hepatitis C treatment: an incipient therapeutic revolution. Trends Mol. Med. 20, 315-321, doi: 10.1016/j.molmed.2014.02.002 (2014
-
(2014)
Trends Mol. Med
, vol.20
, pp. 315-321
-
-
Delemos, A.S.1
Chung, R.T.2
-
6
-
-
84880301028
-
Current progress in development of hepatitis c virus vaccines
-
Liang, T. J. Current progress in development of hepatitis C virus vaccines. Nat. Med. 19, 869-878, doi: 10.1038/nm.3183 (2013
-
(2013)
Nat. Med
, vol.19
, pp. 869-878
-
-
Liang, T.J.1
-
7
-
-
23944452579
-
Prospects for a vaccine against the hepatitis c virus
-
Houghton, M. & Abrignani, S. Prospects for a vaccine against the hepatitis C virus. Nature 436, 961-966, doi: 10.1038/nature04081 (2005
-
(2005)
Nature
, vol.436
, pp. 961-966
-
-
Houghton, M.1
Abrignani, S.2
-
8
-
-
84865742652
-
Prospects for prophylactic and therapeutic vaccines against hepatitis c virus
-
Feinstone, S. M., Hu, D. J. & Major, M. E. Prospects for prophylactic and therapeutic vaccines against hepatitis C virus. Clin. Infect. Dis. 55, S25-S32, doi: 10.1093/cid/cis362 (2012
-
(2012)
Clin. Infect. Dis
, vol.55
, pp. S25-S32
-
-
Feinstone, S.M.1
Hu, D.J.2
Major, M.E.3
-
9
-
-
22344448015
-
Mutational escape from cd8(+ ) t cell immunity: Hcv evolution, from chimpanzees to man
-
Bowen, D. G. & Walker, C. M. Mutational escape from CD8(+ ) T cell immunity: HCV evolution, from chimpanzees to man. J. Exp. Med. 201, 1709-1714, doi: 10.1084/jem.20050808 (2005
-
(2005)
J. Exp. Med
, vol.201
, pp. 1709-1714
-
-
Bowen, D.G.1
Walker, C.M.2
-
10
-
-
7444256169
-
Genetic diversity and evolution of hepatitis c virus-15 years on
-
Simmonds, P. Genetic diversity and evolution of hepatitis C virus-15 years on. J. Gen. Virol. 85, 3173-3188, doi: 10.1099/vir.0.80401-0 (2004
-
(2004)
J. Gen. Virol
, vol.85
, pp. 3173-3188
-
-
Simmonds, P.1
-
11
-
-
0032582538
-
Binding of hepatitis c virus to cd81
-
Pileri, P., et al. Binding of hepatitis C virus to CD81. Science 282, 938-941, doi: 10.1126/science.282.5390.938 (1998
-
(1998)
Science
, vol.282
, pp. 938-941
-
-
Pileri, P.1
-
12
-
-
18644378971
-
The human scavenger receptor class b type i is a novel candidate receptor for the hepatitis c virus
-
Scarselli, E., et al. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21, 5017-5025, doi: 10.1093/emboj/cdf529 (2002
-
(2002)
EMBO J.
, vol.21
, pp. 5017-5025
-
-
Scarselli, E.1
-
13
-
-
84900798422
-
Structure of the core ectodomain of the hepatitis c virus envelope glycoprotein 2
-
Khan, A. G., et al. Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2. Nature 509, 381-384, doi: 10.1038/nature13117 (2014
-
(2014)
Nature
, vol.509
, pp. 381-384
-
-
Khan, A.G.1
-
14
-
-
77649269513
-
The disulfide bonds in glycoprotein e2 of hepatitis c virus reveal the tertiary organization of the molecule
-
Krey, T., et al. The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule. PLoS Pathog. 6, e1000762, doi: 10.1371/journal.ppat.1000762 (2010
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000762
-
-
Krey, T.1
-
15
-
-
34547775736
-
Characterization of fusion determinants points to the involvement of three discrete regions of both e1 and e2 glycoproteins in the membrane fusion process of hepatitis c virus
-
Lavillette, D., et al. Characterization of fusion determinants points to the involvement of three discrete regions of both E1 and E2 glycoproteins in the membrane fusion process of hepatitis C virus. J. Virol. 81, 8752-8765, doi: 10.1128/jvi.02642-06 (2007
-
(2007)
J. Virol
, vol.81
, pp. 8752-8765
-
-
Lavillette, D.1
-
16
-
-
84876514621
-
Hepatitis c virus entry
-
Zeisel, M. B., Felmlee, D. J. & Baumert, T. F. Hepatitis C virus entry. Curr. Top. Microbiol. Immunol. 369, 87-112, doi: 10.1007/978-3-642-27340-7-4 (2013
-
(2013)
Curr. Top. Microbiol. Immunol
, vol.369
, pp. 87-112
-
-
Zeisel, M.B.1
Felmlee, D.J.2
Baumert, T.F.3
-
17
-
-
0034959575
-
Intrahepatic genetic inoculation of hepatitis c virus RNA confers cross-protective immunity
-
Weiner, A. J., et al. Intrahepatic genetic inoculation of hepatitis C virus RNA confers cross-protective immunity. J. Virol. 75, 7142-7148, doi: 10.1128/jvi.75.15.7142-7148.2001 (2001
-
(2001)
J. Virol
, vol.75
, pp. 7142-7148
-
-
Weiner, A.J.1
-
18
-
-
12644289313
-
Prevention of hepatitis c virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein
-
Farci, P., et al. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proc. Natl. Acad. Sci. USA 93, 15394-15399, doi: 10.1073/pnas.93.26.15394 (1996
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15394-15399
-
-
Farci, P.1
-
19
-
-
0027081378
-
Characterization of hypervariable regions in the putative envelope protein of hepatitis c virus
-
Kato, N., et al. Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus. Biochem. Biophys. Res. Commun. 189, 119-127, doi: 10.1016/0006-291x(92)91533-v (1992
-
(1992)
Biochem. Biophys. Res. Commun
, vol.189
, pp. 119-127
-
-
Kato, N.1
-
20
-
-
0030587469
-
A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis c virus can prevent viral infection in cell cultures
-
Shimizu, Y. K., et al A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures. Virology 223, 409-412, doi: 10.1006/viro.1996.0497 (1996
-
(1996)
Virology
, vol.223
, pp. 409-412
-
-
Shimizu, Y.K.1
-
21
-
-
0026025737
-
Variable and hypervariable domains are found in the regions of hcv corresponding to the flavivirus envelope and ns1 proteins and the pestivirus envelope glycoproteins
-
Weiner, A. J., et al. Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology 180, 842-848, doi: 10.1016/0042-6822(91)90104-j (1991
-
(1991)
Virology
, vol.180
, pp. 842-848
-
-
Weiner, A.J.1
-
22
-
-
0034646996
-
The outcome of acute hepatitis c predicted by the evolution of the viral quasispecies
-
Farci, P., et al. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies. Science 288, 339-344, doi: 10.1126/science.288.5464.339 (2000
-
(2000)
Science
, vol.288
, pp. 339-344
-
-
Farci, P.1
-
23
-
-
70450162452
-
Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the e2 evelope glycoprotein of hepatitis c virus
-
Broering, T. J., et al. Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 evelope glycoprotein of hepatitis C virus. J. Virol. 83, 12473-12482, doi: 10.1128/jvi.01138-09 (2009
-
(2009)
J. Virol
, vol.83
, pp. 12473-12482
-
-
Broering, T.J.1
-
24
-
-
84861205239
-
Human monoclonal antibodies to a novel cluster of conformational epitopes on hcv e2 with resistance to neutralization escape in a genotype 2a isolate
-
Keck, Z.-y., et al. Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate. PLoS Pathog. 8, e1002653, doi: 10.1371/journal.ppat.1002653 (2012
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002653
-
-
Keck, Z.-Y.1
-
25
-
-
38049083122
-
Broadly neutralizing antibodies protect against hepatitis c virus quasispecies challenge
-
Law, M., et al. Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nat. Med. 14, 25-27, doi: 10.1038/nm1698 (2008
-
(2008)
Nat. Med
, vol.14
, pp. 25-27
-
-
Law, M.1
-
26
-
-
23844553059
-
Monoclonal antibody ap33 defines a broadly neutralizing epitope on the hepatitis c virus e2 envelope glycoprotein
-
Owsianka, A., et al. Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. J. Virol. 79, 11095-11104, doi: 10.1128/jvi.79.17.11095-11104.2005 (2005
-
(2005)
J. Virol
, vol.79
, pp. 11095-11104
-
-
Owsianka, A.1
-
27
-
-
36048952785
-
Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis c virus
-
Johansson, D. X., et al. Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus. Proc. Natl. Acad. Sci. USA 104, 16269-16274, doi: 10.1073/pnas.0705522104 (2007
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16269-16274
-
-
Johansson, D.X.1
-
28
-
-
37849010852
-
Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis c virus
-
Meunier, J.-C., et al. Isolation and characterization of broadly neutralizing human monoclonal antibodies to the E1 glycoprotein of hepatitis C virus. J. Virol. 82, 966-973, doi: 10.1128/jvi.01872-07 (2008
-
(2008)
J. Virol
, vol.82
, pp. 966-973
-
-
Meunier, J.-C.1
-
29
-
-
84938292659
-
Structure of hepatitis c virus envelope glycoprotein e1 antigenic site 314-324 in complex with antibody igh526
-
Epub ahead of print]
-
Kong, L., Kadam, R. U., Giang, E., Ruwona, T. B., Nieusma, T., Culhane, J. C., Stanfield, R. L., Dawson, P. E., Wilson, I. A., Law, M. Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526. J. Mol. Biol. [Epub ahead of print] doi: 10.1016.j.jmb.2015.06.012 (2015
-
(2015)
J. Mol. Biol
-
-
Kong, L.1
Kadam, R.U.2
Giang, E.3
Ruwona, T.B.4
Nieusma, T.5
Culhane, J.C.6
Stanfield, R.L.7
Dawson, P.E.8
Wilson, I.A.9
Law, M.10
-
30
-
-
84869229723
-
Structure of hepatitis c virus envelope glycoprotein e2 antigenic site 412 to 423 in complex with antibody ap33
-
Kong, L., et al. Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33. J. Virol. 86, 13085-13088, doi: 10.1128/jvi.01939-12 (2012
-
(2012)
J. Virol
, vol.86
, pp. 13085-13088
-
-
Kong, L.1
-
31
-
-
84862177880
-
Structural basis of hepatitis c virus neutralization by broadly neutralizing antibody hcv1
-
Kong, L., et al. Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proc. Natl. Acad. Sci. USA 109, 9499-9504, doi: 10.1073/pnas.1202924109 (2012
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9499-9504
-
-
Kong, L.1
-
32
-
-
84878472445
-
Structural basis of hcv neutralization by human monoclonal antibodies resistant to viral neutralization escape
-
Krey, T., et al. Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape. PLoS Pathog. 9, e1003364, doi: 10.1371/journal.ppat.1003364 (2013
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003364
-
-
Krey, T.1
-
33
-
-
84869233037
-
Toward a hepatitis c virus vaccine: The structural basis of hepatitis c virus neutralization by ap33, a broadly neutralizing antibody
-
Potter, J. A., et al. Toward a hepatitis C virus vaccine: the structural basis of hepatitis C virus neutralization by AP33, a broadly neutralizing antibody. J. Virol. 86, 12923-12932, doi: 10.1128/jvi.02052-12 (2012
-
(2012)
J. Virol
, vol.86
, pp. 12923-12932
-
-
Potter, J.A.1
-
34
-
-
84877720407
-
Glycan shifting on hepatitis c virus (hcv) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies
-
Pantua, H., et al. Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies. J. Mol. Biol. 425, 1899-1914, doi: 10.1016/j.jmb.2013.02.025 (2013
-
(2013)
J. Mol. Biol
, vol.425
, pp. 1899-1914
-
-
Pantua, H.1
-
35
-
-
84888778890
-
Hepatitis c virus e2 envelope glycoprotein core structure
-
Kong, L., et al. Hepatitis C virus E2 envelope glycoprotein core structure. Science 342, 1090-1094, doi: 10.1126/science.1243876 (2013
-
(2013)
Science
, vol.342
, pp. 1090-1094
-
-
Kong, L.1
-
36
-
-
84898023899
-
Unraveling hepatitis c virus structure
-
Fauvelle, C., Felmlee, D. J. & Baumert, T. F. Unraveling hepatitis C virus structure. Cell Res. 24, 385-386, doi: 10.1038/cr.2014.31 (2014
-
(2014)
Cell Res
, vol.24
, pp. 385-386
-
-
Fauvelle, C.1
Felmlee, D.J.2
Baumert, T.F.3
-
37
-
-
82155191729
-
Hepatitis c virus evasion mechanisms from neutralizing antibodies
-
Di Lorenzo, C., Angus, A. G. N. & Patel, A. H. Hepatitis C virus evasion mechanisms from neutralizing antibodies. Viruses-Basel 3, 2280-2300, doi: 10.3390/v3112280 (2011
-
(2011)
Viruses-Basel
, vol.3
, pp. 2280-2300
-
-
Di Lorenzo, C.1
Angus, A.G.N.2
Patel, A.H.3
-
38
-
-
80054987354
-
The hepatitis c virus glycan shield and evasion of the humoral immune response
-
Helle, F., Duverlie, G. & Dubuisson, J. The hepatitis C virus glycan shield and evasion of the humoral immune response. Viruses-Basel 3, 1909-1932, doi: 10.3390/v3101909 (2011
-
(2011)
Viruses-Basel
, vol.3
, pp. 1909-1932
-
-
Helle, F.1
Duverlie, G.2
Dubuisson, J.3
-
39
-
-
78149277602
-
Scaffolding to build a rational vaccine design strategy
-
Burton, D. R. Scaffolding to build a rational vaccine design strategy. Proc. Natl. Acad. Sci. USA 107, 17859-17860, doi: 10.1073/pnas.1012923107 (2010
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 17859-17860
-
-
Burton, D.R.1
-
40
-
-
78650414310
-
Computational protein design using flexible backbone remodeling and resurfacing: Case studies in structurebased antigen design
-
Correia, B. E., et al. Computational protein design using flexible backbone remodeling and resurfacing: case studies in structurebased antigen design. J. Mol. Biol. 405, 284-297, doi: 10.1016/j.jmb.2010.09.061 (2011
-
(2011)
J. Mol. Biol
, vol.405
, pp. 284-297
-
-
Correia, B.E.1
-
41
-
-
78149242586
-
Elicitation of structure-specific antibodies by epitope scaffolds
-
Ofek, G., et al. Elicitation of structure-specific antibodies by epitope scaffolds. Proc. Natl. Acad. Sci. USA 107, 17880-17887, doi: 10.1073/pnas.1004728107 (2010
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 17880-17887
-
-
Ofek, G.1
-
42
-
-
84903757787
-
Transplanting supersites of HIV-1 vulnerability
-
Zhou, T., et al. Transplanting supersites of HIV-1 vulnerability. PLoS ONE 9, e99881, doi: 10.1371/journal.pone.0099881 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e99881
-
-
Zhou, T.1
-
43
-
-
79958059341
-
Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus
-
McLellan, J. S., et al. Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus. J. Mol. Biol. 409, 853-866, doi: 10.1016/j.jmb.2011.04.044 (2011
-
(2011)
J. Mol. Biol
, vol.409
, pp. 853-866
-
-
McLellan, J.S.1
-
44
-
-
84896315237
-
Proof of principle for epitope-focused vaccine design
-
Correia, B. E., et al. Proof of principle for epitope-focused vaccine design. Nature 507, 201-206, doi: 10.1038/nature12966 (2014
-
(2014)
Nature
, vol.507
, pp. 201-206
-
-
Correia, B.E.1
-
45
-
-
84961289547
-
Computational tools for epitope vaccine design and evaluation
-
He, L. & Zhu, J. Computational tools for epitope vaccine design and evaluation. Curr. Opin. Virol. 11, 103-112, doi: 10.1016/j. coviro.2015.03.013 (2015
-
(2015)
Curr. Opin. Virol
, vol.11
, pp. 103-112
-
-
He, L.1
Zhu, J.2
-
46
-
-
77956317558
-
Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope
-
Correia, B. E., et al. Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope. Structure 18, 1116-1126, doi: 10.1016/j.str.2010.06.010 (2010
-
(2010)
Structure
, vol.18
, pp. 1116-1126
-
-
Correia, B.E.1
-
47
-
-
84855258847
-
Computational design of high-Affinity epitope scaffolds by backbone grafting of a linear epitope
-
Azoitei, M. L., et al. Computational design of high-Affinity epitope scaffolds by backbone grafting of a linear epitope. J. Mol. Biol. 415, 175-192, doi: 10.1016/j.jmb.2011.10.003 (2012
-
(2012)
J. Mol. Biol
, vol.415
, pp. 175-192
-
-
Azoitei, M.L.1
-
48
-
-
44949145113
-
Progress and challenges in protein structure prediction
-
Zhang, Y. Progress and challenges in protein structure prediction. Curr. Opin. Struct. Biol. 18, 342-348, doi: 10.1016/i. sbi.2008.02.004 (2008
-
(2008)
Curr. Opin. Struct. Biol
, vol.18
, pp. 342-348
-
-
Zhang, Y.1
-
49
-
-
0036839162
-
Mammoth (matching molecular models obtained from theory an automated method for model comparison
-
Ortiz, A. R., Strauss, C. E. M. & Olmea, O. MAMMOTH (Matching molecular models obtained from theory): An automated method for model comparison. Protein Sci. 11, 2606-2621, doi: 10.1110/ps.0215902 (2002
-
(2002)
Protein Sci
, vol.11
, pp. 2606-2621
-
-
Ortiz, A.R.1
Strauss, C.E.M.2
Olmea, O.3
-
50
-
-
17644392830
-
Tm-Align a protein structure alignment algorithm based on the tm-score
-
Zhang, Y. & Skolnick, J. TM-Align: a protein structure alignment algorithm based on the TM-score. Nucleic Acids Res. 33, 2302-2309, doi: 10.1093/nar/gki524 (2005
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2302-2309
-
-
Zhang, Y.1
Skolnick, J.2
-
51
-
-
84863784145
-
A new size-independent score for pairwise protein structure alignment and its application to structure classification and nucleic-Acid binding prediction
-
Yang, Y., Zhan, J., Zhao, H. & Zhou, Y A new size-independent score for pairwise protein structure alignment and its application to structure classification and nucleic-Acid binding prediction. Proteins 80, 2080-2088, doi: 10.1002/prot.24100 (2012
-
(2012)
Proteins
, vol.80
, pp. 2080-2088
-
-
Yang, Y.1
Zhan, J.2
Zhao, H.3
Zhou, Y.4
-
52
-
-
79959919131
-
Click-Topology-independent comparison of biomolecular 3d structures
-
Nguyen, M. N., Tan, K. P. & Madhusudhan, M. S. CLICK-Topology-independent comparison of biomolecular 3D structures. Nucleic Acids Res. 39, W24-W28, doi: 10.1093/nar/gkr393 (2011
-
(2011)
Nucleic Acids Res
, vol.39
, pp. W24-W28
-
-
Nguyen, M.N.1
Tan, K.P.2
Madhusudhan, M.S.3
-
53
-
-
12944271968
-
Fast: A novel protein structure alignment algorithm
-
Zhu, J. H. & Weng, Z. P. FAST: A novel protein structure alignment algorithm. Proteins 58, 618-627, doi: 10.1002/prot.20331 (2005
-
(2005)
Proteins
, vol.58
, pp. 618-627
-
-
Zhu, J.H.1
Weng, Z.P.2
-
54
-
-
0043180474
-
Pisces: A protein sequence culling server
-
Wang, G. L. & Dunbrack, R. L. PISCES: a protein sequence culling server. Bioinformatics 19, 1589-1591, doi: 10.1093/bioinformatics/btg224 (2003
-
(2003)
Bioinformatics
, vol.19
, pp. 1589-1591
-
-
Wang, G.L.1
Dunbrack, R.L.2
-
55
-
-
0036838311
-
Distance-scaled finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction
-
Zhou, H. Y. & Zhou, Y. Q. Distance-scaled, finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction. Protein Sci. 11, 2714-2726, doi: 10.1110/ps.0217002 (2002
-
(2002)
Protein Sci
, vol.11
, pp. 2714-2726
-
-
Zhou, H.Y.1
Zhou, Y.Q.2
-
56
-
-
51349134973
-
Refining homology models by combining replica-exchange molecular dynamics and statistical potentials
-
Zhu, J., Fan, H., Periole, X., Honig, B. & Mark, A. E. Refining homology models by combining replica-exchange molecular dynamics and statistical potentials. Proteins 72, 1171-1188, doi: 10.1002/prot.22005 (2008
-
(2008)
Proteins
, vol.72
, pp. 1171-1188
-
-
Zhu, J.1
Fan, H.2
Periole, X.3
Honig, B.4
Mark, A.E.5
-
57
-
-
84906330457
-
Fine mapping of murine antibody responses to immunization with a novel soluble form of hepatitis c virus envelope glycoprotein complex
-
Ruwona, T. B., Giang, E., Nieusma, T. & Law, M. Fine mapping of murine antibody responses to immunization with a novel soluble form of hepatitis C virus envelope glycoprotein complex. J. Virol. 88, 10459-10471, doi: 10.1128/jvi.01584-14 (2014
-
(2014)
J. Virol
, vol.88
, pp. 10459-10471
-
-
Ruwona, T.B.1
Giang, E.2
Nieusma, T.3
Law, M.4
-
58
-
-
33644842641
-
Structural insight into interactions between dihydrolipoamide dehydrogenase (e3) and e3 binding protein of human pyruvate dehydrogenase complex
-
Brautigam, C. A., et al. Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex. Structure 14, 611-621, doi: 10.1016/j.str.2006.01.001 (2006
-
(2006)
Structure
, vol.14
, pp. 611-621
-
-
Brautigam, C.A.1
-
59
-
-
27644557445
-
Structural insights into the roles of water and the 2? Hydroxyl of the p site trna in the peptidyl transferase reaction
-
Schmeing, T. M., Huang, K. S., Kitchen, D. E., Strobel, S. A. & Steitz, T. A. Structural insights into the roles of water and the 2? hydroxyl of the P site tRNA in the peptidyl transferase reaction. Mol. Cell 20, 437-448, doi: 10.1016/j.molcel.2005.09.006 (2005
-
(2005)
Mol. Cell
, vol.20
, pp. 437-448
-
-
Schmeing, T.M.1
Huang, K.S.2
Kitchen, D.E.3
Strobel, S.A.4
Steitz, T.A.5
-
60
-
-
0142242265
-
Cell entry of hepatitis c virus requires a set of co-receptors that include the cd81 tetraspanin and the sr-b1 scavenger receptor
-
Bartosch, B., et al. Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor. J. Biol. Chem. 278, 41624-41630, doi: 10.1074/jbc.M305289200 (2003
-
(2003)
J. Biol. Chem
, vol.278
, pp. 41624-41630
-
-
Bartosch, B.1
-
61
-
-
84869085954
-
Interdomain allostery promotes assembly of the poly(a) mrna complex with pabp and eif4g
-
Safaee, N., et al. Interdomain allostery promotes assembly of the poly(A) mRNA complex with PABP and eIF4G. Mol. Cell 48, 375-386, doi: 10.1016/j.molcel.2012.09.001 (2012
-
(2012)
Mol. Cell
, vol.48
, pp. 375-386
-
-
Safaee, N.1
-
62
-
-
33748794562
-
Virus-like particles: Passport to immune recognition
-
Grgacic, E. V. L. & Anderson, D. A. Virus-like particles: Passport to immune recognition. Methods 40, 60-65, doi: 10.1016/j. ymeth.2006.07.018 (2006
-
(2006)
Methods
, vol.40
, pp. 60-65
-
-
Grgacic, E.V.L.1
Anderson, D.A.2
-
63
-
-
37549006787
-
Virus-like particles-universal molecular toolboxes
-
Ludwig, C. & Wagner, R. Virus-like particles-universal molecular toolboxes. Curr. Opin. Biotechnol. 18, 537-545, doi: 10.1016/j. copbio.2007.10.013 (2007
-
(2007)
Curr. Opin. Biotechnol
, vol.18
, pp. 537-545
-
-
Ludwig, C.1
Wagner, R.2
-
64
-
-
45749103230
-
Coming of age of virus-like particle vaccines
-
Jennings, G. T. & Bachmann, M. F. Coming of age of virus-like particle vaccines. Biol. Chem. 389, 521-536, doi: 10.1515/bc.2008.064 (2008
-
(2008)
Biol. Chem
, vol.389
, pp. 521-536
-
-
Jennings, G.T.1
Bachmann, M.F.2
-
65
-
-
84887620206
-
Virus-like particles: The future of microbial factories and cell-free systems as platforms for vaccine development
-
Rodriguez-Limas, W. A., Sekar, K. & Tyo, K. E. J. Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development. Curr. Opin. Biotechnol. 24, 1089-1093, doi: 10.1016/j.copbio.2013.02.008 (2013
-
(2013)
Curr. Opin. Biotechnol
, vol.24
, pp. 1089-1093
-
-
Rodriguez-Limas, W.A.1
Sekar, K.2
Tyo, K.E.J.3
-
66
-
-
0020071393
-
Specific cellular stimulation in the primary immune response: Experimental test of a quantized model
-
Dintzis, R. Z., Vogelstein, B. & Dintzis, H. M. Specific cellular stimulation in the primary immune response: experimental test of a quantized model. Proc. Natl. Acad. Sci. USA 79, 884-888, doi: 10.1073/pnas.79.3.884 (1982
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 884-888
-
-
Dintzis, R.Z.1
Vogelstein, B.2
Dintzis, H.M.3
-
67
-
-
84877609579
-
Rational HIV immunogen design to target specific germline b cell receptors
-
Jardine, J., et al. Rational HIV immunogen design to target specific germline B cell receptors. Science 340, 711-716, doi: 10.1126/science.1234150 (2013
-
(2013)
Science
, vol.340
, pp. 711-716
-
-
Jardine, J.1
-
68
-
-
84879882264
-
Self-Assembling influenza nanoparticle vaccines elicit broadly neutralizing h1n1 antibodies
-
Kanekiyo, M., et al. Self-Assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies. Nature 499, 102-106, doi: 10.1038/nature12202 (2013
-
(2013)
Nature
, vol.499
, pp. 102-106
-
-
Kanekiyo, M.1
-
69
-
-
77953543379
-
Rational antibody-based HIV-1 vaccine design: Current approaches and future directions
-
Walker, L. M. & Burton, D. R. Rational antibody-based HIV-1 vaccine design: current approaches and future directions. Curr. Opin. Immunol. 22, 358-366 (2010
-
(2010)
Curr. Opin. Immunol
, vol.22
, pp. 358-366
-
-
Walker, L.M.1
Burton, D.R.2
-
70
-
-
33645028340
-
The cyclotides and related macrocyclic peptides as scaffolds in drug design
-
Craik, D. J., Cemazar, M. & Daly, N. L. The cyclotides and related macrocyclic peptides as scaffolds in drug design. Curr. Opin. Drug Discovery Dev. 9, 251-260 (2006
-
(2006)
Curr. Opin. Drug Discovery Dev
, vol.9
, pp. 251-260
-
-
Craik, D.J.1
Cemazar, M.2
Daly, N.L.3
-
71
-
-
0036489968
-
The cyclotides: Novel macrocyclic peptides as scaffolds in drug design
-
Craik, D. J., Simonsen, S. & Daly, N. L. The cyclotides: Novel macrocyclic peptides as scaffolds in drug design. Curr. Opin. Drug Discovery Dev. 5, 251-260 (2002
-
(2002)
Curr. Opin. Drug Discovery Dev
, vol.5
, pp. 251-260
-
-
Craik, D.J.1
Simonsen, S.2
Daly, N.L.3
-
73
-
-
48149098354
-
A new generation of protein therapeutics
-
Stumpp, M. T., Binz, H. K. & Amstutz, P. DARPins: A new generation of protein therapeutics. Drug Discovery Today 13, 695-701, doi: 10.1016/j.drudis.2008.04.013 (2008
-
(2008)
Drug Discovery Today
, vol.13
, pp. 695-701
-
-
Stumpp, M.T.1
Binz, H.K.2
Darpins, A.P.3
-
74
-
-
79956017135
-
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
-
Fleishman, S. J., et al. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 332, 816-821, doi: 10.1126/science.1202617 (2011
-
(2011)
Science
, vol.332
, pp. 816-821
-
-
Fleishman, S.J.1
-
75
-
-
0038386050
-
3d-jury: A simple approach to improve protein structure predictions
-
Ginalski, K., Elofsson, A., Fischer, D. & Rychlewski, L. 3D-Jury: a simple approach to improve protein structure predictions. Bioinformatics 19, 1015-1018, doi: 10.1093/bioinformatics/btg124 (2003
-
(2003)
Bioinformatics
, vol.19
, pp. 1015-1018
-
-
Ginalski, K.1
Elofsson, A.2
Fischer, D.3
Rychlewski, L.4
-
76
-
-
0037624841
-
3d-shotgun: A novel, cooperative, fold-recognition meta-predictor
-
Fischer, D. 3D-SHOTGUN: A novel, cooperative, fold-recognition meta-predictor. Proteins 51, 434-441, doi: 10.1002/prot.10357 (2003
-
(2003)
Proteins
, vol.51
, pp. 434-441
-
-
Fischer, D.1
-
77
-
-
84892785219
-
Bioengineering virus-like particles as vaccines
-
Lua, L. H. L., et al. Bioengineering virus-like particles as vaccines. Biotechnol. Bioeng. 111, 425-440, doi: 10.1002/bit.25159 (2014
-
(2014)
Biotechnol. Bioeng
, vol.111
, pp. 425-440
-
-
Lua, L.H.L.1
-
78
-
-
79960011784
-
Structural model of the trpp2/pkd1 c-Terminal coiled-coil complex produced by a combined computational and experimental approach
-
Zhu, J., et al. Structural model of the TRPP2/PKD1 C-Terminal coiled-coil complex produced by a combined computational and experimental approach. Proc. Natl. Acad. Sci. USA 108, 10133-10138, doi: 10.1073/pnas.1017669108 (2011
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 10133-10138
-
-
Zhu, J.1
-
79
-
-
38549154569
-
Loop modeling: Sampling, filtering, and scoring
-
Soto, C. S., Fasnacht, M., Zhu, J., Forrest, L. & Honig, B. Loop modeling: Sampling, filtering, and scoring. Proteins 70, 834-843, doi: 10.1002/prot.21612 (2008
-
(2008)
Proteins
, vol.70
, pp. 834-843
-
-
Soto, C.S.1
Fasnacht, M.2
Zhu, J.3
Forrest, L.4
Honig, B.5
-
80
-
-
33749037718
-
Structural refinement of protein segments containing secondary structure elements: Local sampling, knowledge-based potentials, and clustering
-
Zhu, J., Xie, L. & Honig, B. Structural refinement of protein segments containing secondary structure elements: Local sampling, knowledge-based potentials, and clustering. Proteins 65, 463-479, doi: 10.1002/prot.21085 (2006
-
(2006)
Proteins
, vol.65
, pp. 463-479
-
-
Zhu, J.1
Xie, L.2
Honig, B.3
-
81
-
-
77649336168
-
Building and refining protein models within cryo-electron microscopy density maps based on homology modeling and multiscale structure refinement
-
Zhu, J., Cheng, L., Fang, Q., Zhou, Z. H. & Honig, B. Building and refining protein models within cryo-electron microscopy density maps based on homology modeling and multiscale structure refinement. J. Mol. Biol. 397, 835-851, doi: 10.1016/j. jmb.2010.01.041 (2010
-
(2010)
J. Mol. Biol
, vol.397
, pp. 835-851
-
-
Zhu, J.1
Cheng, L.2
Fang, Q.3
Zhou, Z.H.4
Honig, B.5
-
82
-
-
0035838974
-
Extending the accuracy limits of prediction for side-chain conformations
-
Xiang, Z. X. & Honig, B. Extending the accuracy limits of prediction for side-chain conformations. J. Mol. Biol. 311, 421-430, doi: 10.1006/jmbi.2001.4865 (2001
-
(2001)
J. Mol. Biol
, vol.311
, pp. 421-430
-
-
Xiang, Z.X.1
Honig, B.2
-
83
-
-
0036643430
-
Fast and accurate side-chain topology and energy refinement (faster) as a new method for protein structure optimization
-
Desmet, J., Spriet, J. & Lasters, I. Fast and Accurate Side-Chain Topology and Energy Refinement (FASTER) as a new method for protein structure optimization. Proteins 48, 31-43, doi: 10.1002/prot.10131 (2002
-
(2002)
Proteins
, vol.48
, pp. 31-43
-
-
Desmet, J.1
Spriet, J.2
Lasters, I.3
-
84
-
-
84988112508
-
An efficient Newton-like method for molecular mechanics energy minimization of large molecules
-
Ponder, J. W. & Richards, F. M. An efficient Newton-like method for molecular mechanics energy minimization of large molecules. J. Comput. Chem. 8, 1016-1024, doi: 10.1002/jcc.540080710 (1987
-
(1987)
J. Comput. Chem
, vol.8
, pp. 1016-1024
-
-
Ponder, J.W.1
Richards, F.M.2
-
85
-
-
33645941402
-
The opls [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin
-
Jorgensen, W. L. & Tiradorives, J. The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. J. Am. Chem. Soc. 110, 1657-1666, doi: 10.1021/ja00214a001 (1988
-
(1988)
J. Am. Chem. Soc
, vol.110
, pp. 1657-1666
-
-
Jorgensen, W.L.1
Tiradorives, J.2
-
86
-
-
0029633168
-
Gromacs a message-passing parallel molecular dynamics implementation
-
Berendsen, H. J. C., Vanderspoel, D. & Vandrunen, R. GROMACS: A message-passing parallel molecular dynamics implementation. Comput. Phys. Commun. 91, 43-56, doi: 10.1016/0010-4655(95)00042-e (1995
-
(1995)
Comput. Phys. Commun
, vol.91
, pp. 43-56
-
-
Berendsen, H.J.C.1
Vanderspoel, D.2
Vandrunen, R.3
-
87
-
-
0035789518
-
Gromacs 3.0: A package for molecular simulation and trajectory analysis
-
Lindahl, E., Hess, B. & van der Spoel, D. GROMACS 3.0: a package for molecular simulation and trajectory analysis. J. Mol. Model. 7, 306-317, doi: 10.1007/s008940100045 (2001
-
(2001)
J. Mol. Model
, vol.7
, pp. 306-317
-
-
Lindahl, E.1
Hess, B.2
Van Der Spoel, D.3
-
88
-
-
33645961739
-
A smooth particle mesh ewald method
-
Essmann, U., et al A smooth particle mesh Ewald method. J. Chem. Phys. 103, 8577-8593, doi: 10.1063/1.470117 (1995
-
(1995)
J. Chem. Phys
, vol.103
, pp. 8577-8593
-
-
Essmann, U.1
-
89
-
-
0000388705
-
Lincs a linear constraint solver for molecular simulations
-
Hess, B., Bekker, H., Berendsen, H. J. C. & Fraaije, J. LINCS: A linear constraint solver for molecular simulations. J. Comput. Chem. 18, 1463-1472, doi: 10.1002/(sici)1096-987x(199709)18: 12 3.0.co; 2-h (1997
-
(1997)
J. Comput. Chem
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, J.4
-
90
-
-
84986440341
-
Settle: An analytical version of the shake and rattle algorithm for rigid water models
-
Miyamoto, S. & Kollman, P. A. Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models. J. Comput. Chem. 13, 952-962, doi: 10.1002/jcc.540130805 (1992
-
(1992)
J. Comput. Chem
, vol.13
, pp. 952-962
-
-
Miyamoto, S.1
Kollman, P.A.2
-
91
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen, H. J. C., Postma, J. P. M., Vangunsteren, W. F., Dinola, A. & Haak, J. R. Molecular dynamics with coupling to an external bath. J. Chem. Phys. 81, 3684-3690, doi: 10.1063/1.448118 (1984
-
(1984)
J. Chem. Phys
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Vangunsteren, W.F.3
Dinola, A.4
Haak, J.R.5
|